SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ohc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6G_A_VD3A701_1 (CYTOCHROME P450 2R1)	4ohc	OROTATE PHOSPHORIBOSYLTRANSF ERASE (Burkholderia cenocepacia)	5 / 12	LEU A 179 LEU A 127 ALA A 181 GLY A 80 ILE A 66	None	1.05A	3c6gA-4ohcA: undetectable	3c6gA-4ohcA: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR4_X_PNTX101_0 (PROTEIN S100-B)	4ohc	OROTATE PHOSPHORIBOSYLTRANSF ERASE (Burkholderia cenocepacia)	3 / 3	CYH A 156 HIS A 180 PHE A 157	None	1.15A	3cr4X-4ohcA: undetectable	3cr4X-4ohcA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AWU_A_4CHA503_0 (OXIDOREDUCTASE, FMN-BINDING)	4ohc	OROTATE PHOSPHORIBOSYLTRANSF ERASE (Burkholderia cenocepacia)	4 / 6	TYR A 162 TRP A 186 PHE A 209 PHE A 165	None	1.32A	4awuA-4ohcA: undetectable	4awuA-4ohcA: 22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB5_A_010A609_0 (HNL ISOENZYME 5)	4ohc	OROTATE PHOSPHORIBOSYLTRANSF ERASE (Burkholderia cenocepacia)	5 / 11	ARG A 147 ALA A 79 VAL A 126 LEU A 128 VAL A 153	None	1.20A	5eb5A-4ohcA: undetectable	5eb5A-4ohcA: 20.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3C6G_A_VD3A701_1","CYTOCHROME P450 2R1","4ohc","OROTATE PHOSPHORIBOSYLTRANSFERASE","Burkholderia cenocepacia",5,"LEU A 179;LEU A 127;ALA A 181;GLY A  80;ILE A  66","None","1.05A","3c6gA-4ohcA:undetectable","3c6gA-4ohcA:21.97"],["3CR4_X_PNTX101_0","PROTEIN S100-B","4ohc","OROTATE PHOSPHORIBOSYLTRANSFERASE","Burkholderia cenocepacia",3,"CYH A 156;HIS A 180;PHE A 157","None","1.15A","3cr4X-4ohcA:undetectable","3cr4X-4ohcA:17.43"],["4AWU_A_4CHA503_0","OXIDOREDUCTASE, FMN-BINDING","4ohc","OROTATE PHOSPHORIBOSYLTRANSFERASE","Burkholderia cenocepacia",4,"TYR A 162;TRP A 186;PHE A 209;PHE A 165","None","1.32A","4awuA-4ohcA:undetectable","4awuA-4ohcA:22.19"],["5EB5_A_010A609_0","HNL ISOENZYME 5","4ohc","OROTATE PHOSPHORIBOSYLTRANSFERASE","Burkholderia cenocepacia",5,"ARG A 147;ALA A  79;VAL A 126;LEU A 128;VAL A 153","None","1.20A","5eb5A-4ohcA:undetectable","5eb5A-4ohcA:20.27"]]