SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ohj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 7 ASP A 207
GLY A 192
GLY A 191
ASN A 234
 None
 0.74A 2c49B-4ohjA:
undetectable		 2c49B-4ohjA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 6 THR A 168
THR A 129
ASN A  77
ASP A  79
 None
 1.18A 2okcA-4ohjA:
undetectable		 2okcA-4ohjA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 8 ILE A 166
ASP A 170
ARG A 174
TRP A 194
 None
 0.96A 2v57A-4ohjA:
undetectable		 2v57A-4ohjA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 8 ILE A 166
ASP A 170
ARG A 174
TRP A 194
 None
 0.95A 2v57C-4ohjA:
undetectable		 2v57C-4ohjA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 6 THR A  59
ASN A 105
GLY A 127
ILE A  75
 None
 1.03A 3w9tF-4ohjA:
undetectable		 3w9tF-4ohjA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 6 ILE A  85
VAL A 102
VAL A 128
SER A  63
 None
 0.88A 5jwaH-4ohjA:
undetectable		 5jwaH-4ohjA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		4 / 5 PHE A  87
SER A  72
ASN A  77
GLN A 124
 None
 1.37A 5kpcA-4ohjA:
undetectable		 5kpcA-4ohjA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		5 / 10 PRO A 157
ILE A 173
ILE A 223
ILE A 226
ILE A 221
 None
 0.97A 5murE-4ohjA:
undetectable		 5murE-4ohjA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		3 / 3 LEU A 177
LEU A 208
ARG A 174
 None
 0.70A 6fgcA-4ohjA:
undetectable		 6fgcA-4ohjA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 4ohj TOXIC SHOCK SYNDROME
TOXIN-1
(Staphylococcus
aureus) 		3 / 3 LEU A 177
LEU A 208
ARG A 174
 None
 0.66A 6fgdA-4ohjA:
undetectable		 6fgdA-4ohjA:
20.05