SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ohq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A  60
ASP A  28
LEU A  25
GLY A 239
PHE A 242
 None
 1.41A 1i00A-4ohqA:
undetectable		 1i00A-4ohqA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A  60
ASP A  28
LEU A  25
GLY A 239
PHE A 242
 None
 1.39A 1i00B-4ohqA:
undetectable		 1i00B-4ohqA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 GLY A 210
VAL A 213
ALA A 182
ASN A 217
ILE A 227
 None
 1.05A 1likA-4ohqA:
undetectable		 1likA-4ohqA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 PHE A 145
ALA A 188
ILE A 128
ILE A 207
 None
 0.87A 1oniD-4ohqA:
undetectable
1oniF-4ohqA:
1.5		 1oniD-4ohqA:
21.10
1oniF-4ohqA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 LEU A 148
PHE A 151
ALA A 152
LEU A 193
 None
 0.94A 1ukbA-4ohqA:
undetectable		 1ukbA-4ohqA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 PHE A 242
VAL A  40
ILE A  93
ILE A 125
CYH A 127
 None
 1.28A 2ft9A-4ohqA:
undetectable		 2ft9A-4ohqA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 ILE A  60
ASP A  28
LEU A  25
GLY A 239
PHE A 242
 None
 1.34A 2tsrC-4ohqA:
undetectable		 2tsrC-4ohqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A  60
ASP A  28
LEU A  25
GLY A 239
PHE A 242
 None
 1.42A 2tsrD-4ohqA:
undetectable		 2tsrD-4ohqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 PHE A   8
ILE A 227
ASN A 160
PHE A 230
 None
 1.19A 3octA-4ohqA:
undetectable		 3octA-4ohqA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 ILE A 125
GLY A  10
VAL A  41
SER A  63
 None
 0.87A 4a3uB-4ohqA:
7.1		 4a3uB-4ohqA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 SER A  63
GLY A  64
ILE A 125
ILE A 161
LEU A 118
 None
 1.01A 4dt8B-4ohqA:
undetectable		 4dt8B-4ohqA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A  60
ASP A  28
LEU A  25
GLY A 239
PHE A 242
 None
 1.47A 4eb4C-4ohqA:
undetectable		 4eb4C-4ohqA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 ILE A  60
ASP A  28
LEU A  25
GLY A 239
PHE A 242
 None
 1.43A 4eb4D-4ohqA:
undetectable		 4eb4D-4ohqA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 ILE A 161
ALA A 126
VAL A 155
PRO A 156
 None
 0.80A 4jltA-4ohqA:
undetectable		 4jltA-4ohqA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 ALA A  32
ALA A 243
VAL A 246
LEU A  56
VAL A  40
 None
 1.03A 5eb5A-4ohqA:
undetectable		 5eb5A-4ohqA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 GLY A  10
ASP A  39
PHE A   8
ASN A  12
 None
 1.00A 5mvsA-4ohqA:
undetectable		 5mvsA-4ohqA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4ohq TRIOSEPHOSPHATE
ISOMERASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 7 ILE A  60
ASP A  28
LEU A  25
GLY A 239
PHE A 242
 None
 1.32A 5nooB-4ohqA:
undetectable		 5nooB-4ohqA:
23.67