SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ohs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 4ohs FAR-RED FLUORESCENT
PROTEIN AQ143
(Actinia
equina) 		4 / 6 ARG A 181
GLY A  87
LYS A  67
THR A  68
 None
None
CH6  A  63 ( 4.0A)
None
 1.10A 2m2oB-4ohsA:
undetectable		 2m2oB-4ohsA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4ohs FAR-RED FLUORESCENT
PROTEIN AQ143
(Actinia
equina) 		4 / 6 THR A  14
GLY A  28
ILE A  43
LYS A  66
 None
None
None
CH6  A  63 ( 3.6A)
 1.07A 4acbC-4ohsA:
undetectable		 4acbC-4ohsA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 4ohs FAR-RED FLUORESCENT
PROTEIN AQ143
(Actinia
equina) 		4 / 5 GLY A  37
ALA A 216
PHE A  69
GLU A 214
 None
None
None
CH6  A  63 ( 2.8A)
 0.89A 4m93B-4ohsA:
undetectable
4m93C-4ohsA:
undetectable		 4m93B-4ohsA:
22.00
4m93C-4ohsA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 4ohs FAR-RED FLUORESCENT
PROTEIN AQ143
(Actinia
equina) 		4 / 5 GLY A  37
SER A 215
ALA A 216
PHE A  69
 None
 1.01A 4m93B-4ohsA:
undetectable
4m93C-4ohsA:
undetectable		 4m93B-4ohsA:
22.00
4m93C-4ohsA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 4ohs FAR-RED FLUORESCENT
PROTEIN AQ143
(Actinia
equina) 		3 / 3 CYH A 164
LYS A 163
HIS A 169
 None
 1.24A 5js5A-4ohsA:
undetectable		 5js5A-4ohsA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 4ohs FAR-RED FLUORESCENT
PROTEIN AQ143
(Actinia
equina) 		3 / 3 LYS A 136
ASP A 166
ILE A  57
 None
 0.48A 5kc4E-4ohsA:
undetectable		 5kc4E-4ohsA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4ohs FAR-RED FLUORESCENT
PROTEIN AQ143
(Actinia
equina) 		4 / 6 PHE A 126
PRO A 127
GLY A 130
ASN A 129
 None
 0.87A 5x24A-4ohsA:
undetectable		 5x24A-4ohsA:
19.55