SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oi3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.15A 1p6kA-4oi3A:
undetectable		 1p6kA-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.12A 1p6kB-4oi3A:
undetectable		 1p6kB-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.19A 1rs6A-4oi3A:
undetectable		 1rs6A-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.11A 1rs6B-4oi3A:
undetectable		 1rs6B-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.13A 1rs7B-4oi3A:
undetectable		 1rs7B-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.19A 1zzqA-4oi3A:
undetectable		 1zzqA-4oi3A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.12A 1zzqB-4oi3A:
undetectable		 1zzqB-4oi3A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.15A 1zzuA-4oi3A:
undetectable		 1zzuA-4oi3A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.13A 1zzuB-4oi3A:
undetectable		 1zzuB-4oi3A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.08A 3n62B-4oi3A:
undetectable		 3n62B-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.28A 3n66B-4oi3A:
undetectable		 3n66B-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 7 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.33A 4kcnB-4oi3A:
undetectable		 4kcnB-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.30A 5vunA-4oi3A:
undetectable		 5vunA-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.35A 5vunB-4oi3A:
undetectable		 5vunB-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.31A 5vuoB-4oi3A:
undetectable		 5vuoB-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4oi3 NICKEL RESPONSIVE
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.31A 6auuB-4oi3A:
undetectable		 6auuB-4oi3A:
11.76