SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		3 / 3 ASP A 345
PHE A 350
ARG A 348
 None
 0.88A 2a3aA-4oibA:
undetectable		 2a3aA-4oibA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU A  97
PRO A  98
LEU A 190
ARG A 128
 None
 0.75A 2hrcA-4oibA:
undetectable		 2hrcA-4oibA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU A  97
PRO A  98
LEU A 190
ARG A 128
 None
 0.75A 2pnjB-4oibA:
undetectable		 2pnjB-4oibA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		3 / 3 LEU A  97
PRO A  98
LEU A 190
 None
 0.46A 2qd5B-4oibA:
undetectable		 2qd5B-4oibA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		3 / 3 PRO A 118
LEU A 171
ARG A  88
 None
 0.86A 3aqiB-4oibA:
undetectable		 3aqiB-4oibA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU A 190
ALA A 156
VAL A 103
PRO A 102
 None
 1.10A 3gv1B-4oibA:
undetectable		 3gv1B-4oibA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU A  97
PRO A  98
LEU A 190
ARG A 128
 None
 0.66A 3hcoB-4oibA:
undetectable		 3hcoB-4oibA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		3 / 3 GLY A  81
GLU A  63
THR A  64
 None
 0.52A 4kouA-4oibA:
undetectable		 4kouA-4oibA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 5 ARG A 119
GLY A 147
ALA A 148
GLY A 117
 None
 0.86A 4u9uA-4oibA:
undetectable		 4u9uA-4oibA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 5 ARG A 119
GLY A 147
ALA A 148
GLY A 117
 None
 0.82A 4u9uB-4oibA:
undetectable		 4u9uB-4oibA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4oib INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 12 PRO A 114
GLY A 117
GLY A 147
ALA A 120
LEU A 171
 None
 0.97A 5c0oG-4oibA:
undetectable		 5c0oG-4oibA:
22.83