SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 4oic BET V I
ALLERGEN-LIKE
PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		4 / 7 THR A 177
TRP B 339
GLY A 171
ASP A 170
 None
 0.95A 1bu5A-4oicA:
undetectable		 1bu5A-4oicA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 PHE B 172
LEU B 196
ALA B 198
LEU B 220
TYR B 204
 None
 1.02A 1cbrA-4oicB:
undetectable		 1cbrA-4oicB:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 PHE B 172
LEU B 196
ALA B 198
LEU B 220
TYR B 204
 None
 1.02A 1cbrB-4oicB:
undetectable		 1cbrB-4oicB:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		5 / 12 LEU A  21
HIS A  29
LEU A  48
GLY A  12
PHE A 144
 None
 1.45A 1d4fB-4oicA:
undetectable		 1d4fB-4oicA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 4oic BET V I
ALLERGEN-LIKE
PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 11 SER A 100
VAL A  99
GLY B 208
MET B 350
PHE A  76
 None
None
None
None
A8S  A 301 (-4.8A)
 1.27A 1iolA-4oicA:
undetectable		 1iolA-4oicA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		4 / 7 SER B 315
ALA B 296
SER B 301
ALA B 303
 None
 0.95A 1k5qA-4oicB:
0.0
1k5qB-4oicB:
undetectable		 1k5qA-4oicB:
17.06
1k5qB-4oicB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifA-4oicA:
undetectable		 1kifA-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifB-4oicA:
undetectable		 1kifB-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifC-4oicA:
undetectable		 1kifC-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifD-4oicA:
undetectable		 1kifD-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifE-4oicA:
undetectable		 1kifE-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifF-4oicA:
undetectable		 1kifF-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifG-4oicA:
undetectable		 1kifG-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.11A 1kifH-4oicA:
undetectable		 1kifH-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		4 / 5 ILE B 450
LEU B 388
VAL B 382
CYH B 380
 None
 0.99A 1mz9C-4oicB:
undetectable		 1mz9C-4oicB:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.03A 1ve9A-4oicA:
undetectable		 1ve9A-4oicA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.06A 2du8G-4oicA:
undetectable		 2du8G-4oicA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4oic BET V I
ALLERGEN-LIKE
(Oryza
sativa) 		4 / 5 TYR A  73
ILE A  63
ARG A  94
GLY A  68
 None
 1.10A 2du8J-4oicA:
undetectable		 2du8J-4oicA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4oic BET V I
ALLERGEN-LIKE
PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 HIS B 207
LEU B 359
LEU A 187
SER B 353
GLY B 346
 None
 1.25A 3kk6B-4oicB:
undetectable		 3kk6B-4oicB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 GLY B 280
GLY B 299
ASP B 300
ASP B 356
ILE B 363
 None
 0.85A 3prsA-4oicB:
undetectable		 3prsA-4oicB:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		4 / 7 LEU B 348
ASP B 356
SER B 353
GLU B 163
 None
 1.29A 4aq7A-4oicB:
undetectable		 4aq7A-4oicB:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		3 / 3 ASP B 164
TRP B 150
SER B 301
 None
 1.04A 4lrhA-4oicB:
undetectable		 4lrhA-4oicB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		4 / 6 ARG B 159
ASP B 386
GLY B 387
ASP B 390
 None
MN  B 501 ( 2.9A)
None
MN  B 503 (-2.3A)
 1.11A 5hp1A-4oicB:
undetectable		 5hp1A-4oicB:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 VAL B 284
ALA B 303
SER B 315
GLY B 387
LEU B 388
 None
 1.16A 5m5cB-4oicB:
undetectable		 5m5cB-4oicB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 10 VAL B 284
ALA B 303
SER B 315
GLY B 387
LEU B 388
 None
 1.18A 5m5cE-4oicB:
undetectable		 5m5cE-4oicB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 VAL B 284
LEU B 381
ALA B 303
SER B 315
LEU B 388
 None
 1.29A 5nd4B-4oicB:
undetectable		 5nd4B-4oicB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 9 LEU B 228
LEU B 224
ILE B 371
PRO B 367
ALA B 296
 None
 1.02A 5og9A-4oicB:
undetectable		 5og9A-4oicB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 LEU B 228
LEU B 224
ILE B 371
PRO B 367
ALA B 296
 None
 1.06A 5og9B-4oicB:
undetectable		 5og9B-4oicB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 10 LEU B 359
TYR B 358
ASP B 356
VAL B 344
GLY B 346
 None
 1.33A 5zbdA-4oicB:
undetectable		 5zbdA-4oicB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 10 LEU B 359
TYR B 358
ASP B 356
VAL B 344
GLY B 346
 None
 1.35A 5zbdB-4oicB:
undetectable		 5zbdB-4oicB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		6 / 12 LEU B 348
PRO B 320
GLY B 341
SER B 351
ILE B 363
GLY B 346
 None
 1.36A 5zhmB-4oicB:
undetectable		 5zhmB-4oicB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		5 / 12 VAL B 452
SER B 451
VAL B 455
GLY B 151
VAL B 284
 None
 1.20A 6a94B-4oicB:
undetectable		 6a94B-4oicB:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6
(Oryza
sativa) 		4 / 5 GLU B 145
VAL B 147
LEU B 149
HIS B 409
 None
 1.31A 6dyoA-4oicB:
undetectable		 6dyoA-4oicB:
10.53