SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oiv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
ILE A 339
ILE A 356
MET A 369
TYR A 373
 XX9  A 501 (-4.1A)
None
XX9  A 501 ( 4.6A)
XX9  A 501 (-4.5A)
None
 1.03A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
MET A 294
ILE A 356
MET A 369
TYR A 373
 XX9  A 501 (-4.1A)
XX9  A 501 ( 4.3A)
XX9  A 501 ( 4.6A)
XX9  A 501 (-4.5A)
None
 0.83A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
MET A 294
PHE A 333
ILE A 356
MET A 369
 XX9  A 501 (-4.1A)
XX9  A 501 ( 4.3A)
XX9  A 501 (-4.7A)
XX9  A 501 ( 4.6A)
XX9  A 501 (-4.5A)
 0.81A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
MET A 294
PHE A 333
SER A 336
ILE A 356
 XX9  A 501 (-4.1A)
XX9  A 501 ( 4.3A)
XX9  A 501 (-4.7A)
XX9  A 501 (-4.2A)
XX9  A 501 ( 4.6A)
 0.66A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
MET A 294
SER A 336
ILE A 356
TYR A 373
 XX9  A 501 (-4.1A)
XX9  A 501 ( 4.3A)
XX9  A 501 (-4.2A)
XX9  A 501 ( 4.6A)
None
 0.94A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
PHE A 333
ILE A 339
ILE A 356
MET A 369
 XX9  A 501 (-4.1A)
XX9  A 501 (-4.7A)
None
XX9  A 501 ( 4.6A)
XX9  A 501 (-4.5A)
 0.80A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
PHE A 333
SER A 336
ILE A 339
ILE A 356
 XX9  A 501 (-4.1A)
XX9  A 501 (-4.7A)
XX9  A 501 (-4.2A)
None
XX9  A 501 ( 4.6A)
 0.79A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 291
SER A 336
ILE A 339
ILE A 356
TYR A 373
 XX9  A 501 (-4.1A)
XX9  A 501 (-4.2A)
None
XX9  A 501 ( 4.6A)
None
 0.93A 1osvB-4oivA:
24.8		 1osvB-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OT7_A_CHCA1001_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 ARG A 335
SER A 336
ILE A 339
ILE A 356
TYR A 373
 None
XX9  A 501 (-4.2A)
None
XX9  A 501 ( 4.6A)
None
 0.92A 1ot7A-4oivA:
24.4		 1ot7A-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OT7_A_CHCA1001_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 PHE A 333
ARG A 335
SER A 336
ILE A 339
ILE A 356
 XX9  A 501 (-4.7A)
None
XX9  A 501 (-4.2A)
None
XX9  A 501 ( 4.6A)
 0.88A 1ot7A-4oivA:
24.4		 1ot7A-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 291
ARG A 335
SER A 336
ILE A 339
ILE A 356
TYR A 373
 XX9  A 501 (-4.1A)
None
XX9  A 501 (-4.2A)
None
XX9  A 501 ( 4.6A)
None
 0.91A 1ot7B-4oivA:
24.6		 1ot7B-4oivA:
93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 291
MET A 294
ARG A 335
SER A 336
ILE A 356
TYR A 373
 XX9  A 501 (-4.1A)
XX9  A 501 ( 4.3A)
None
XX9  A 501 (-4.2A)
XX9  A 501 ( 4.6A)
None
 1.01A 1ot7B-4oivA:
24.6		 1ot7B-4oivA:
93.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		4 / 6 ASP A 404
ILE A 402
LEU A 323
GLU A 409
 None
 1.06A 2ya7A-4oivA:
undetectable		 2ya7A-4oivA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		4 / 6 ASP A 404
ILE A 402
LEU A 323
GLU A 409
 None
 1.07A 2ya7B-4oivA:
undetectable		 2ya7B-4oivA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		4 / 4 VAL A 301
ASP A 262
LEU A 257
ARG A 335
 None
 1.14A 2ziaA-4oivA:
undetectable		 2ziaA-4oivA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		4 / 6 VAL A 303
LYS A 307
GLN A 313
LEU A 256
 None
 1.03A 3bjwE-4oivA:
undetectable		 3bjwE-4oivA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 422
LEU A 419
LEU A 416
GLN A 412
LEU A 441
 None
 1.21A 3d90B-4oivA:
16.2		 3d90B-4oivA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		4 / 6 ASN A 297
TYR A 264
GLU A 338
ILE A 339
 None
 1.21A 3q5sA-4oivA:
undetectable		 3q5sA-4oivA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		4 / 4 LEU A 388
MET A 381
ILE A 394
LEU A 334
 None
 1.41A 5nfpA-4oivA:
16.4		 5nfpA-4oivA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4oiv BILE ACID RECEPTOR
(Homo
sapiens) 		3 / 3 TYR A 386
ARG A 335
THR A 390
 None
 1.02A 5z84J-4oivA:
undetectable		 5z84J-4oivA:
15.46