SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 LEU A 209
LEU A 354
LEU A 238
VAL A 254
ILE A 326
 None
 1.22A 1ee2A-4oj5A:
undetectable		 1ee2A-4oj5A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 LEU A 209
LEU A 354
LEU A 272
VAL A 254
ILE A 326
 None
 1.19A 1ee2A-4oj5A:
undetectable		 1ee2A-4oj5A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 LEU A 209
LEU A 354
LEU A 238
VAL A 254
ILE A 326
 None
 1.23A 1ee2B-4oj5A:
undetectable		 1ee2B-4oj5A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 LEU A 209
LEU A 354
LEU A 272
VAL A 254
ILE A 326
 None
 1.12A 1ee2B-4oj5A:
undetectable		 1ee2B-4oj5A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 8 PRO A 480
PRO A 538
GLY A 506
PHE A 493
THR A 503
 None
 1.39A 1h4oB-4oj5A:
undetectable		 1h4oB-4oj5A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 9 PRO A 480
PRO A 538
GLY A 506
PHE A 493
THR A 503
 None
 1.40A 1h4oC-4oj5A:
undetectable
1h4oD-4oj5A:
undetectable		 1h4oC-4oj5A:
12.02
1h4oD-4oj5A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 9 PRO A 480
PRO A 538
GLY A 506
PHE A 493
THR A 503
 None
 1.42A 1h4oH-4oj5A:
undetectable		 1h4oH-4oj5A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 6 HIS A 694
ILE A 693
ALA A 739
VAL A 707
 None
 0.99A 1hk1A-4oj5A:
undetectable		 1hk1A-4oj5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 5 SER A 624
THR A 586
GLU A 646
GLY A 647
 None
 1.28A 1icrA-4oj5A:
undetectable
1icrB-4oj5A:
undetectable		 1icrA-4oj5A:
15.19
1icrB-4oj5A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 5 GLU A 646
GLY A 647
SER A 624
THR A 586
 None
 1.30A 1icrA-4oj5A:
undetectable
1icrB-4oj5A:
undetectable		 1icrA-4oj5A:
15.19
1icrB-4oj5A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 5 SER A 624
THR A 586
GLU A 646
GLY A 647
 None
 1.29A 1icvC-4oj5A:
undetectable
1icvD-4oj5A:
undetectable		 1icvC-4oj5A:
15.19
1icvD-4oj5A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 5 GLU A 646
GLY A 647
SER A 624
THR A 586
 None
 1.32A 1icvC-4oj5A:
undetectable
1icvD-4oj5A:
undetectable		 1icvC-4oj5A:
15.19
1icvD-4oj5A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 ALA A  76
VAL A  47
LEU A  59
THR A  53
LEU A  72
 None
 1.21A 1jipA-4oj5A:
undetectable		 1jipA-4oj5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 SER A 401
LEU A 286
GLY A 346
ALA A 347
SER A 382
 None
 1.07A 1pxxC-4oj5A:
undetectable		 1pxxC-4oj5A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 LEU A 504
VAL A 533
LEU A 556
MET A 519
LEU A 544
 None
 1.14A 1rlbF-4oj5A:
undetectable		 1rlbF-4oj5A:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
THR A 695
LEU A 672
GLY A 674
PHE A 683
 None
 1.01A 1xwfA-4oj5A:
undetectable		 1xwfA-4oj5A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
THR A 695
LEU A 672
GLY A 674
PHE A 683
 None
 1.02A 1xwfB-4oj5A:
undetectable		 1xwfB-4oj5A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 ILE A 389
VAL A 341
GLY A 340
LEU A 354
SER A 261
 None
 0.76A 2bxeA-4oj5A:
undetectable		 2bxeA-4oj5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 ILE A 389
VAL A 341
GLY A 340
LEU A 354
SER A 261
 None
 0.78A 2bxeB-4oj5A:
undetectable		 2bxeB-4oj5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 LEU A 329
LEU A 238
LEU A 205
LYS A 206
LEU A 272
 None
 1.03A 2ceoA-4oj5A:
undetectable		 2ceoA-4oj5A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 6 ARG A 467
ASN A 531
PRO A 526
ALA A 529
 None
 1.11A 2ejfB-4oj5A:
undetectable		 2ejfB-4oj5A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 7 ARG A 467
ASN A 531
PRO A 526
ALA A 529
 None
 1.11A 2ejgA-4oj5A:
undetectable		 2ejgA-4oj5A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HH9_A_VIBA702_1
(THIAMIN
PYROPHOSPHOKINASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 9 ASP A 311
VAL A 397
SER A 446
SER A 401
ASN A 402
 None
 1.38A 2hh9A-4oj5A:
0.0
2hh9B-4oj5A:
0.0		 2hh9A-4oj5A:
18.60
2hh9B-4oj5A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HH9_B_VIBB701_1
(THIAMIN
PYROPHOSPHOKINASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 9 VAL A 397
SER A 446
SER A 401
ASN A 402
ASP A 311
 None
 1.39A 2hh9A-4oj5A:
0.0
2hh9B-4oj5A:
0.0		 2hh9A-4oj5A:
18.60
2hh9B-4oj5A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 LEU A 329
LEU A 238
LEU A 205
LYS A 206
LEU A 272
 None
 0.99A 2riwA-4oj5A:
undetectable
2riwB-4oj5A:
undetectable		 2riwA-4oj5A:
18.53
2riwB-4oj5A:
4.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 LEU A 329
LEU A 238
LEU A 205
LYS A 206
LEU A 272
 None
 1.04A 2xn6A-4oj5A:
undetectable
2xn6B-4oj5A:
undetectable		 2xn6A-4oj5A:
18.48
2xn6B-4oj5A:
3.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 8 ASN A 700
ILE A 752
VAL A 706
TYR A 729
 None
 0.87A 2yoeB-4oj5A:
undetectable
2yoeC-4oj5A:
undetectable		 2yoeB-4oj5A:
16.56
2yoeC-4oj5A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 7 PHE A  36
LEU A  72
LEU A  87
LEU A  78
 None
 0.65A 3bgdB-4oj5A:
undetectable		 3bgdB-4oj5A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_A_FOLA270_0
(PTERIDINE REDUCTASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 SER A 500
PHE A 493
TYR A 520
PRO A 480
GLU A 483
 None
 1.10A 3bmcA-4oj5A:
undetectable		 3bmcA-4oj5A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_B_FOLB270_0
(PTERIDINE REDUCTASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 SER A 500
PHE A 493
TYR A 520
PRO A 480
GLU A 483
 None
 1.10A 3bmcB-4oj5A:
0.1		 3bmcB-4oj5A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_D_FOLD270_0
(PTERIDINE REDUCTASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 SER A 500
PHE A 493
TYR A 520
PRO A 480
GLU A 483
 None
 1.21A 3bmcD-4oj5A:
undetectable		 3bmcD-4oj5A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 5 PRO A 591
ILE A 589
PRO A 606
TYR A 626
 None
 1.36A 3d9lA-4oj5A:
undetectable
3d9lY-4oj5A:
undetectable		 3d9lA-4oj5A:
12.37
3d9lY-4oj5A:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 GLY A 630
GLY A 649
GLY A 674
ASN A 593
VAL A 592
 None
 0.85A 3elwA-4oj5A:
undetectable		 3elwA-4oj5A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 THR A 441
VAL A 339
LEU A 331
SER A 379
THR A 351
 None
 1.18A 3frqA-4oj5A:
undetectable		 3frqA-4oj5A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
LEU A 627
LEU A 672
GLY A 674
PHE A 683
 None
 1.11A 3g1uA-4oj5A:
undetectable		 3g1uA-4oj5A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
LEU A 627
LEU A 672
GLY A 674
PHE A 683
 None
 1.12A 3g1uB-4oj5A:
undetectable		 3g1uB-4oj5A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
LEU A 627
LEU A 672
GLY A 674
PHE A 683
 None
 1.14A 3g1uC-4oj5A:
undetectable		 3g1uC-4oj5A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
LEU A 627
LEU A 672
GLY A 674
PHE A 683
 None
 1.10A 3g1uD-4oj5A:
undetectable		 3g1uD-4oj5A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
LEU A 627
LEU A 672
GLY A 674
PHE A 683
 None
 1.11A 3glqA-4oj5A:
undetectable		 3glqA-4oj5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
LEU A 627
LEU A 672
GLY A 674
PHE A 683
 None
 1.18A 3glqB-4oj5A:
undetectable		 3glqB-4oj5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		3 / 3 ILE A 496
SER A 471
SER A 499
 None
 0.63A 3iltH-4oj5A:
undetectable		 3iltH-4oj5A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 6 SER A 500
PHE A 493
TYR A 520
PRO A 480
 None
 1.02A 3jqaA-4oj5A:
undetectable		 3jqaA-4oj5A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 6 SER A 500
PHE A 493
TYR A 520
PRO A 480
 None
 1.06A 3jqaB-4oj5A:
undetectable		 3jqaB-4oj5A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 6 SER A 500
PHE A 493
TYR A 520
PRO A 480
 None
 0.97A 3jqaC-4oj5A:
undetectable		 3jqaC-4oj5A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 6 SER A 500
PHE A 493
TYR A 520
PRO A 480
 None
 1.00A 3jqaD-4oj5A:
undetectable		 3jqaD-4oj5A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 8 ILE A 496
SER A 471
SER A 499
GLY A 466
ASN A 531
 None
 1.37A 3lslA-4oj5A:
undetectable
3lslD-4oj5A:
undetectable		 3lslA-4oj5A:
16.10
3lslD-4oj5A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 8 ASN A 531
ILE A 496
SER A 471
SER A 499
GLY A 466
 None
 1.36A 3lslA-4oj5A:
undetectable
3lslD-4oj5A:
undetectable		 3lslA-4oj5A:
16.10
3lslD-4oj5A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 667
LEU A 627
LEU A 672
GLY A 674
PHE A 683
 None
 1.12A 3n58A-4oj5A:
undetectable		 3n58A-4oj5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 ILE A 326
ILE A 284
SER A 285
LEU A 374
HIS A 384
 None
 1.07A 3o1cA-4oj5A:
undetectable		 3o1cA-4oj5A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 ALA A  76
LEU A  87
VAL A  85
LEU A  42
ALA A  82
 None
 1.11A 3ozuA-4oj5A:
undetectable		 3ozuA-4oj5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 PHE A 450
ASN A 408
ALA A 410
ILE A 455
PHE A 462
 None
 1.25A 3t3qA-4oj5A:
undetectable		 3t3qA-4oj5A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 PHE A 450
ASN A 408
ALA A 410
ILE A 455
PHE A 462
 None
 1.22A 3t3qB-4oj5A:
undetectable		 3t3qB-4oj5A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 PHE A 450
ASN A 408
ALA A 410
ILE A 455
PHE A 462
 None
 1.24A 3t3qC-4oj5A:
undetectable		 3t3qC-4oj5A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 PHE A 450
ASN A 408
ALA A 410
ILE A 455
PHE A 462
 None
 1.24A 3t3qD-4oj5A:
undetectable		 3t3qD-4oj5A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 272
LEU A 331
LEU A 354
ILE A 256
ILE A 284
 None
 1.15A 4a7aB-4oj5A:
undetectable		 4a7aB-4oj5A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 GLY A 759
ASP A 758
ILE A 730
ASN A 714
LEU A 763
 None
 1.15A 4a81A-4oj5A:
undetectable		 4a81A-4oj5A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 8 TYR A 705
CYH A 726
VAL A 743
ILE A 752
 None
 1.07A 4aftD-4oj5A:
undetectable
4aftE-4oj5A:
undetectable		 4aftD-4oj5A:
14.42
4aftE-4oj5A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		3 / 3 ARG A 467
TYR A 551
ASN A 531
 None
 0.82A 4ffwB-4oj5A:
undetectable		 4ffwB-4oj5A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 ILE A 326
THR A 351
HIS A 384
TRP A 343
LEU A 387
 None
 1.33A 4pbhA-4oj5A:
undetectable		 4pbhA-4oj5A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 6 LEU A 669
THR A 677
LEU A 672
SER A 673
 None
 0.93A 4pwjA-4oj5A:
undetectable		 4pwjA-4oj5A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		6 / 12 GLY A 647
ILE A 675
ILE A 589
PRO A 641
VAL A 643
ILE A 607
 None
 1.29A 4q5mA-4oj5A:
undetectable		 4q5mA-4oj5A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		4 / 5 ARG A 467
GLY A 445
ALA A 444
GLY A 466
 None
 0.94A 4u9uB-4oj5A:
undetectable		 4u9uB-4oj5A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 11 SER A 518
GLY A 571
VAL A 570
ASP A 572
ILE A 573
 None
 1.23A 5i3cC-4oj5A:
undetectable		 5i3cC-4oj5A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 ASP A 304
LEU A 272
ILE A 326
ILE A 389
ALA A 396
 None
 1.18A 5vc0A-4oj5A:
undetectable		 5vc0A-4oj5A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 TYR A 717
ILE A 693
LEU A 667
PHE A 645
LEU A 672
 None
 1.20A 5y7pB-4oj5A:
undetectable		 5y7pB-4oj5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 TYR A 717
ILE A 693
LEU A 667
PHE A 645
LEU A 672
 None
 1.21A 5y7pD-4oj5A:
undetectable		 5y7pD-4oj5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 10 TYR A 717
ILE A 693
LEU A 667
PHE A 645
LEU A 672
 None
 1.19A 5y7pH-4oj5A:
undetectable		 5y7pH-4oj5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 GLU A 385
VAL A 440
GLN A 376
PRO A 480
ILE A 455
 None
 1.40A 6becA-4oj5A:
undetectable
6becB-4oj5A:
undetectable
6becC-4oj5A:
undetectable		 6becA-4oj5A:
23.57
6becB-4oj5A:
23.57
6becC-4oj5A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 LEU A 248
VAL A 341
ILE A 258
LEU A 374
ILE A 284
 None
 0.92A 6dgxB-4oj5A:
undetectable		 6dgxB-4oj5A:
7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 VAL A 337
LEU A 354
LEU A 387
ALA A 283
LEU A 329
 None
 1.01A 6ew0B-4oj5A:
undetectable		 6ew0B-4oj5A:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 VAL A 337
LEU A 354
LEU A 387
ALA A 283
LEU A 329
 None
 1.01A 6ew0D-4oj5A:
undetectable		 6ew0D-4oj5A:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 VAL A 337
LEU A 354
LEU A 387
ALA A 283
LEU A 329
 None
 1.01A 6ew0H-4oj5A:
undetectable		 6ew0H-4oj5A:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 4oj5 TAILSPIKE PROTEIN
(Escherichia
virus
CBA120) 		5 / 12 VAL A 337
LEU A 354
LEU A 387
ALA A 283
LEU A 329
 None
 1.02A 6ew0I-4oj5A:
undetectable		 6ew0I-4oj5A:
7.21