SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 4oje EFF-1A
(Caenorhabditis
elegans) 		5 / 10 GLY H 415
ASP H 412
ILE H 410
ILE H 498
ALA H 458
 None
 0.95A 1sh9B-4ojeH:
undetectable		 1sh9B-4ojeH:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 4oje EFF-1A
(Caenorhabditis
elegans) 		5 / 12 ALA H  73
LEU H 246
ILE H 233
PHE H 403
PHE H  66
 None
 1.16A 1y0xX-4ojeH:
undetectable		 1y0xX-4ojeH:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4oje EFF-1A
(Caenorhabditis
elegans) 		3 / 3 PRO H 174
ASP H 181
GLU H 179
 None
 0.89A 3v4tC-4ojeH:
undetectable		 3v4tC-4ojeH:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4oje EFF-1A
(Caenorhabditis
elegans) 		4 / 7 HIS H 405
HIS H  39
LEU H 463
SER H 408
 None
None
NAG  H1101 ( 4.5A)
None
 0.98A 5m8rA-4ojeH:
undetectable		 5m8rA-4ojeH:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4oje EFF-1A
(Caenorhabditis
elegans) 		4 / 8 HIS H 405
HIS H  39
LEU H 463
SER H 408
 None
None
NAG  H1101 ( 4.5A)
None
 1.02A 5m8rB-4ojeH:
undetectable		 5m8rB-4ojeH:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4oje EFF-1A
(Caenorhabditis
elegans) 		4 / 8 HIS H 405
HIS H  39
LEU H 463
SER H 408
 None
None
NAG  H1101 ( 4.5A)
None
 1.01A 5m8rD-4ojeH:
undetectable		 5m8rD-4ojeH:
19.46