SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4okj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 135
ILE A 156
TRP A 124
 None
 0.99A 1nodB-4okjA:
undetectable		 1nodB-4okjA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 135
ILE A 156
TRP A 124
 None
 1.02A 1qomA-4okjA:
undetectable		 1qomA-4okjA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 135
ILE A 156
TRP A 124
 None
 1.03A 2nodB-4okjA:
undetectable		 2nodB-4okjA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 135
ILE A 156
TRP A 124
 None
 0.94A 3e7iB-4okjA:
undetectable		 3e7iB-4okjA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 152
ASP A   6
ASP A 148
 None
MG  A 202 (-3.1A)
None
 0.91A 3jb3A-4okjA:
undetectable		 3jb3A-4okjA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 135
ILE A 156
TRP A 124
 None
 1.07A 3nw2B-4okjA:
undetectable		 3nw2B-4okjA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		4 / 8 TYR A   5
LEU A  73
LEU A  77
THR A 112
 None
 1.18A 5hs6A-4okjA:
undetectable		 5hs6A-4okjA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 120
PHE A 153
ARG A   2
TYR A   3
LEU A  99
 None
 1.24A 5ljcA-4okjA:
undetectable		 5ljcA-4okjA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1
(Mycobacterium
tuberculosis) 		6 / 12 ILE A  21
ALA A  98
GLN A 101
ARG A  66
LEU A  18
LEU A  87
 None
 1.26A 5z12C-4okjA:
undetectable		 5z12C-4okjA:
21.79