SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4okv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTA_H_MFXH101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA)	4okv	ANTI-PLATELET AGGREGATION PROTEIN (Anopheles stephensi)	4 / 6	SER E 218 ARG E 245 GLY E 243 GLU E 242	None	1.00A	5btaA-4okvE: undetectable 5btaB-4okvE: undetectable 5btaC-4okvE: undetectable	5btaA-4okvE: 13.48 5btaB-4okvE: 14.77 5btaC-4okvE: 13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTC_G_CPFG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	4okv	ANTI-PLATELET AGGREGATION PROTEIN (Anopheles stephensi)	4 / 6	SER E 218 ARG E 245 GLY E 243 GLU E 242	None	1.04A	5btcA-4okvE: undetectable 5btcC-4okvE: undetectable 5btcD-4okvE: undetectable	5btcA-4okvE: 13.48 5btcC-4okvE: 13.48 5btcD-4okvE: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTC_G_CPFG102_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	4okv	ANTI-PLATELET AGGREGATION PROTEIN (Anopheles stephensi)	4 / 6	SER E 218 ARG E 245 GLY E 243 GLU E 242	None	1.03A	5btcA-4okvE: undetectable 5btcB-4okvE: undetectable 5btcC-4okvE: undetectable	5btcA-4okvE: 13.48 5btcB-4okvE: 14.77 5btcC-4okvE: 13.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5BTA_H_MFXH101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCACGTAA","4okv","ANTI-PLATELET AGGREGATION PROTEIN","Anopheles stephensi",4,"SER E 218;ARG E 245;GLY E 243;GLU E 242","None","1.00A","5btaA-4okvE:undetectable;5btaB-4okvE:undetectable;5btaC-4okvE:undetectable","5btaA-4okvE:13.48;5btaB-4okvE:14.77;5btaC-4okvE:13.48"],["5BTC_G_CPFG101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","4okv","ANTI-PLATELET AGGREGATION PROTEIN","Anopheles stephensi",4,"SER E 218;ARG E 245;GLY E 243;GLU E 242","None","1.04A","5btcA-4okvE:undetectable;5btcC-4okvE:undetectable;5btcD-4okvE:undetectable","5btcA-4okvE:13.48;5btcC-4okvE:13.48;5btcD-4okvE:14.77"],["5BTC_G_CPFG102_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","4okv","ANTI-PLATELET AGGREGATION PROTEIN","Anopheles stephensi",4,"SER E 218;ARG E 245;GLY E 243;GLU E 242","None","1.03A","5btcA-4okvE:undetectable;5btcB-4okvE:undetectable;5btcC-4okvE:undetectable","5btcA-4okvE:13.48;5btcB-4okvE:14.77;5btcC-4okvE:13.48"]]