SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oky'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		5 / 9 ARG C 281
SER C 284
GLY C  95
ALA C 156
THR C  94
 None
 1.50A 1c9sA-4okyC:
undetectable
1c9sB-4okyC:
undetectable		 1c9sA-4okyC:
15.83
1c9sB-4okyC:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		5 / 9 ARG C 281
SER C 284
GLY C  95
ALA C 156
THR C  94
 None
 1.49A 1gtfF-4okyC:
undetectable
1gtfG-4okyC:
undetectable		 1gtfF-4okyC:
15.83
1gtfG-4okyC:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		3 / 3 GLU C 228
ASN C 217
TRP C 205
 None
 1.15A 1r15C-4okyC:
undetectable		 1r15C-4okyC:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		3 / 3 GLU C 228
ASN C 217
TRP C 205
 None
 1.10A 1r15D-4okyC:
undetectable		 1r15D-4okyC:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		3 / 3 GLU C 228
ASN C 217
TRP C 205
 None
 1.12A 1r15E-4okyC:
undetectable		 1r15E-4okyC:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		3 / 3 GLU C 228
ASN C 217
TRP C 205
 None
 1.08A 1r15F-4okyC:
undetectable		 1r15F-4okyC:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		4 / 6 LEU C   8
LYS C  13
VAL C  28
ILE C  14
 None
 0.84A 2hyyA-4okyC:
undetectable		 2hyyA-4okyC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		4 / 6 LEU C   8
LYS C  13
VAL C  28
ILE C  14
 None
 0.88A 2hyyB-4okyC:
undetectable		 2hyyB-4okyC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		4 / 8 HIS C  29
ASN C  25
ILE C  24
PHE C  38
 None
 1.27A 3ccfB-4okyC:
undetectable		 3ccfB-4okyC:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		3 / 3 GLU C 239
ALA C 266
PHE C 279
 None
 0.65A 4v1fA-4okyC:
undetectable		 4v1fA-4okyC:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4oky RESTRICTION
ENDONUCLEASE PVURTS1
I
(Proteus
vulgaris) 		3 / 3 GLU C 239
ALA C 266
PHE C 279
 None
 0.66A 4v1fC-4okyC:
undetectable		 4v1fC-4okyC:
12.67