SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ol9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 179
THR A 277
ASN A 263
TYR A 209
 None
 1.29A 1afsA-4ol9A:
undetectable		 1afsA-4ol9A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 179
THR A 277
ASN A 263
TYR A 209
 None
 1.29A 1afsB-4ol9A:
undetectable		 1afsB-4ol9A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.17A 1dz4A-4ol9A:
undetectable		 1dz4A-4ol9A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.14A 1dz4B-4ol9A:
undetectable		 1dz4B-4ol9A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.15A 1dz9A-4ol9A:
undetectable		 1dz9A-4ol9A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 VAL A   8
GLY A   9
ALA A  81
LEU A  85
 NAP  A 301 ( 4.8A)
NAP  A 301 (-3.3A)
NAP  A 301 ( 4.3A)
None
 0.78A 1e7bB-4ol9A:
2.6		 1e7bB-4ol9A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.15A 1t88B-4ol9A:
undetectable		 1t88B-4ol9A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.72A 1usqB-4ol9A:
undetectable		 1usqB-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.72A 1usqC-4ol9A:
undetectable		 1usqC-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.71A 1usqD-4ol9A:
undetectable		 1usqD-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.11A 1uyuA-4ol9A:
undetectable		 1uyuA-4ol9A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.13A 1uyuB-4ol9A:
undetectable		 1uyuB-4ol9A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ASN A 181
LEU A 183
ALA A 184
MET A 243
SER A 194
 OXM  A 302 (-3.2A)
None
None
None
None
 0.87A 2aa5A-4ol9A:
undetectable		 2aa5A-4ol9A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ASN A 181
LEU A 183
ALA A 184
MET A 243
SER A 194
 OXM  A 302 (-3.2A)
None
None
None
None
 0.90A 2aa5B-4ol9A:
undetectable		 2aa5B-4ol9A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  41
VAL A 118
VAL A 122
ILE A  70
 None
None
NAP  A 301 (-4.3A)
None
 1.09A 2hyyB-4ol9A:
undetectable		 2hyyB-4ol9A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.67A 2jkjA-4ol9A:
undetectable		 2jkjA-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.67A 2jkjB-4ol9A:
undetectable		 2jkjB-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.67A 2jkjC-4ol9A:
undetectable		 2jkjC-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.70A 2jklB-4ol9A:
undetectable		 2jklB-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.22A 2m56A-4ol9A:
undetectable		 2m56A-4ol9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.08A 2zuhA-4ol9A:
undetectable		 2zuhA-4ol9A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 265
VAL A 122
LEU A  98
ILE A 121
GLN A 104
 None
NAP  A 301 (-4.3A)
None
None
None
 1.45A 3elzC-4ol9A:
undetectable		 3elzC-4ol9A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A   9
GLN A  77
ILE A  70
VAL A  17
VAL A  13
 NAP  A 301 (-3.3A)
NAP  A 301 (-3.1A)
None
None
NAP  A 301 (-3.7A)
 1.40A 3fi0D-4ol9A:
undetectable		 3fi0D-4ol9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A   9
GLN A  77
ILE A  70
VAL A  17
VAL A  13
 NAP  A 301 (-3.3A)
NAP  A 301 (-3.1A)
None
None
NAP  A 301 (-3.7A)
 1.32A 3fi0R-4ol9A:
undetectable		 3fi0R-4ol9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 162
LEU A 142
ALA A  96
ILE A  70
LEU A   7
 None
 1.10A 3fl9A-4ol9A:
undetectable		 3fl9A-4ol9A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 162
LEU A 142
ALA A  96
ILE A  70
LEU A   7
 None
 1.04A 3fl9F-4ol9A:
undetectable		 3fl9F-4ol9A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.09A 3fwgA-4ol9A:
undetectable		 3fwgA-4ol9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.08A 3fwgB-4ol9A:
undetectable		 3fwgB-4ol9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  26
ALA A  18
ILE A   5
LEU A  30
LEU A  41
 None
 1.29A 3lcvB-4ol9A:
undetectable		 3lcvB-4ol9A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 TRP A 259
PRO A 285
GLY A 293
PRO A 294
 None
 1.30A 3ucbB-4ol9A:
undetectable		 3ucbB-4ol9A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 145
GLY A 147
ALA A 150
ALA A 116
 None
 0.79A 3ur0B-4ol9A:
undetectable		 3ur0B-4ol9A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.05A 3wrhE-4ol9A:
undetectable		 3wrhE-4ol9A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.09A 3wrjE-4ol9A:
undetectable		 3wrjE-4ol9A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A 101
TRP A 175
ARG A 268
GLU A 220
 None
 1.25A 4bqfA-4ol9A:
3.4		 4bqfA-4ol9A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 225
LEU A 214
GLU A 231
ALA A 222
ARG A 176
 None
 1.47A 4cpzE-4ol9A:
undetectable		 4cpzE-4ol9A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 231
ASP A 225
LEU A 214
ALA A 222
ARG A 176
 None
 1.40A 4cpzE-4ol9A:
undetectable		 4cpzE-4ol9A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.06A 4ek1A-4ol9A:
undetectable		 4ek1A-4ol9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ASN A 181
LEU A 183
ALA A 184
MET A 243
ALA A 239
 OXM  A 302 (-3.2A)
None
None
None
None
 0.99A 4fn9A-4ol9A:
undetectable		 4fn9A-4ol9A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.11A 4g3rA-4ol9A:
undetectable		 4g3rA-4ol9A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.12A 4kkyX-4ol9A:
undetectable		 4kkyX-4ol9A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.15A 4l49A-4ol9A:
undetectable		 4l49A-4ol9A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.10A 4l4cA-4ol9A:
undetectable		 4l4cA-4ol9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.08A 4l4eA-4ol9A:
undetectable		 4l4eA-4ol9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.10A 4l4fA-4ol9A:
undetectable		 4l4fA-4ol9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 SER A 246
ASP A 250
GLN A  77
 OXM  A 302 ( 2.7A)
NAP  A 301 ( 4.8A)
NAP  A 301 (-3.1A)
 0.94A 4oltA-4ol9A:
undetectable
4oltB-4ol9A:
undetectable		 4oltA-4ol9A:
22.43
4oltB-4ol9A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 GLN A  77
SER A 246
ASP A 250
 NAP  A 301 (-3.1A)
OXM  A 302 ( 2.7A)
NAP  A 301 ( 4.8A)
 0.95A 4qwpA-4ol9A:
undetectable
4qwpB-4ol9A:
undetectable		 4qwpA-4ol9A:
23.12
4qwpB-4ol9A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 GLU A 258
ILE A 121
ALA A  72
 NAP  A 301 (-2.8A)
None
None
 0.66A 4wnwB-4ol9A:
undetectable		 4wnwB-4ol9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 154
LEU A 156
ILE A  70
ALA A  96
ILE A   5
 None
 0.97A 5xiwB-4ol9A:
undetectable		 5xiwB-4ol9A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 249
LEU A 257
ASP A 250
VAL A 188
GLY A 185
 None
None
NAP  A 301 ( 4.8A)
None
None
 1.21A 5zbdA-4ol9A:
undetectable		 5zbdA-4ol9A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 249
LEU A 257
ASP A 250
VAL A 188
GLY A 185
 None
None
NAP  A 301 ( 4.8A)
None
None
 1.21A 5zbdB-4ol9A:
undetectable		 5zbdB-4ol9A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 153
LEU A  21
VAL A  17
VAL A 164
 None
 1.10A 6cp4A-4ol9A:
undetectable		 6cp4A-4ol9A:
20.85