SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4olo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7B_A_BEZA1529_0 (BENZOATE-COENZYME A LIGASE)	4olo	BMC DOMAIN PROTEIN (Clostridiales bacterium 1_7_47FAA)	5 / 9	ALA A 86 ALA A 34 GLY A 78 GLY A 36 ILE A 5	None	1.12A	2v7bA-4oloA: undetectable	2v7bA-4oloA: 10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_F_H3PF552_1 (GLUTAMATE DEHYDROGENASE)	4olo	BMC DOMAIN PROTEIN (Clostridiales bacterium 1_7_47FAA)	4 / 7	ILE A 76 LYS A 33 ILE A 5 TYR A 3	None	0.98A	3eteD-4oloA: undetectable 3eteF-4oloA: undetectable	3eteD-4oloA: 12.58 3eteF-4oloA: 12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EAT_B_BEZB1000_0 (BENZOATE-COENZYME A LIGASE)	4olo	BMC DOMAIN PROTEIN (Clostridiales bacterium 1_7_47FAA)	6 / 9	ALA A 86 ALA A 34 GLY A 78 ILE A 35 GLY A 36 ILE A 5	None	1.10A	4eatB-4oloA: undetectable	4eatB-4oloA: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGJ_A_CTYA402_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	4olo	BMC DOMAIN PROTEIN (Clostridiales bacterium 1_7_47FAA)	5 / 12	ILE A 63 GLU A 84 ALA A 55 ALA A 52 GLY A 57	None	1.09A	5igjA-4oloA: undetectable	5igjA-4oloA: 17.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2V7B_A_BEZA1529_0","BENZOATE-COENZYME A LIGASE","4olo","BMC DOMAIN PROTEIN","Clostridiales bacterium 1_7_47FAA",5,"ALA A  86;ALA A  34;GLY A  78;GLY A  36;ILE A   5","None","1.12A","2v7bA-4oloA:undetectable","2v7bA-4oloA:10.78"],["3ETE_F_H3PF552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","4olo","BMC DOMAIN PROTEIN","Clostridiales bacterium 1_7_47FAA",4,"ILE A  76;LYS A  33;ILE A   5;TYR A   3","None","0.98A","3eteD-4oloA:undetectable;3eteF-4oloA:undetectable","3eteD-4oloA:12.58;3eteF-4oloA:12.58"],["4EAT_B_BEZB1000_0","BENZOATE-COENZYME A LIGASE","4olo","BMC DOMAIN PROTEIN","Clostridiales bacterium 1_7_47FAA",6,"ALA A  86;ALA A  34;GLY A  78;ILE A  35;GLY A  36;ILE A   5","None","1.10A","4eatB-4oloA:undetectable","4eatB-4oloA:12.60"],["5IGJ_A_CTYA402_1","MACROLIDE 2'-PHOSPHOTRANSFERASE","4olo","BMC DOMAIN PROTEIN","Clostridiales bacterium 1_7_47FAA",5,"ILE A  63;GLU A  84;ALA A  55;ALA A  52;GLY A  57","None","1.09A","5igjA-4oloA:undetectable","5igjA-4oloA:17.11"]]