SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4olq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 11 PHE A  61
ALA A  62
LEU A  27
LEU A 116
LEU A  91
 None
 0.93A 1ha2A-4olqA:
2.0		 1ha2A-4olqA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		4 / 8 ILE A 162
THR A 159
PRO A 135
LEU A 163
 None
 0.84A 1hmyA-4olqA:
undetectable		 1hmyA-4olqA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		4 / 7 PHE A  70
SER A  83
ILE A  73
GLY A 139
 None
 0.86A 2v0mB-4olqA:
undetectable		 2v0mB-4olqA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 12 PHE A 131
ALA A 174
ALA A 171
VAL A 184
GLU A 106
 None
 1.23A 3cwkA-4olqA:
undetectable		 3cwkA-4olqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 12 LEU A  27
VAL A 133
GLY A 111
GLY A  64
LEU A 150
 None
 1.32A 3dh0A-4olqA:
undetectable		 3dh0A-4olqA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 11 GLY A  59
ALA A  58
ASP A  57
VAL A  17
ILE A 105
 None
 1.15A 3ebzB-4olqA:
undetectable		 3ebzB-4olqA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		4 / 6 VAL A 101
ILE A  35
ILE A  51
LEU A  52
 None
 0.63A 3hegA-4olqA:
undetectable		 3hegA-4olqA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		3 / 3 ASN A  43
GLU A  98
ARG A 209
 None
 1.10A 3wxoA-4olqA:
undetectable		 3wxoA-4olqA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 12 LEU A 116
ILE A   5
ALA A  26
SER A  28
LEU A  27
 None
 1.01A 4m11A-4olqA:
undetectable		 4m11A-4olqA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 12 LEU A 116
ILE A   5
ALA A  26
SER A  28
LEU A  27
 None
 1.06A 4o1zB-4olqA:
undetectable		 4o1zB-4olqA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 12 GLY A 178
LEU A 177
ALA A 152
VAL A 133
PHE A 169
 None
 1.05A 4wnwB-4olqA:
undetectable		 4wnwB-4olqA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 10 ALA A 125
ILE A 105
GLY A 132
PHE A 131
GLY A 107
 None
 1.20A 5i6xA-4olqA:
undetectable		 5i6xA-4olqA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 12 GLY A 113
ILE A  35
ALA A 119
ALA A 120
ILE A  94
 None
 0.91A 5kb6B-4olqA:
undetectable		 5kb6B-4olqA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 12 TYR A 142
GLY A 111
LEU A 116
GLY A 113
GLY A 112
 None
 0.99A 5wyqB-4olqA:
undetectable		 5wyqB-4olqA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4olq ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN
(Hyphomonas
neptunium) 		5 / 10 PHE A 169
GLY A 172
ILE A 105
ALA A 129
PHE A  70
 None
 1.43A 5zjiA-4olqA:
undetectable
5zjiJ-4olqA:
undetectable		 5zjiA-4olqA:
14.35
5zjiJ-4olqA:
9.93