SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ols'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 4ols ENDOLYSIN
(Staphylococcus
virus
G15) 		4 / 7 GLU A 298
HIS A 340
LEU A 359
ILE A 213
 None
 1.17A 1tuvA-4olsA:
undetectable		 1tuvA-4olsA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 4ols ENDOLYSIN
(Staphylococcus
virus
G15) 		5 / 11 VAL A 283
GLY A 246
TYR A 250
TYR A 370
PHE A 302
 None
 1.47A 3qxyB-4olsA:
undetectable
3qxyQ-4olsA:
undetectable		 3qxyB-4olsA:
16.52
3qxyQ-4olsA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4ols ENDOLYSIN
(Staphylococcus
virus
G15) 		3 / 3 GLU A 311
TYR A 244
GLU A 253
 None
 0.71A 4ryaA-4olsA:
undetectable		 4ryaA-4olsA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4ols ENDOLYSIN
(Staphylococcus
virus
G15) 		4 / 5 HIS A 264
HIS A 214
VAL A 212
ALA A 279
 None
ZN  A 501 (-3.2A)
None
None
 1.16A 5i3bB-4olsA:
undetectable		 5i3bB-4olsA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4ols ENDOLYSIN
(Staphylococcus
virus
G15) 		4 / 5 ALA A 279
TYR A 244
GLN A 260
ILE A 255
 None
 1.27A 6g9bA-4olsA:
undetectable
6g9bB-4olsA:
undetectable		 6g9bA-4olsA:
17.41
6g9bB-4olsA:
21.76