SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4om7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 4om7 TOLL-LIKE RECEPTOR 6
(Homo
sapiens) 		3 / 3 TRP A 763
PHE A 773
TRP A 774
 None
 1.01A 1r15C-4om7A:
2.6		 1r15C-4om7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 4om7 TOLL-LIKE RECEPTOR 6
(Homo
sapiens) 		3 / 3 TRP A 763
PHE A 773
TRP A 774
 None
 1.00A 1r15F-4om7A:
2.6		 1r15F-4om7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 4om7 TOLL-LIKE RECEPTOR 6
(Homo
sapiens) 		3 / 3 TRP A 763
PHE A 773
TRP A 774
 None
 1.01A 1r15G-4om7A:
2.4		 1r15G-4om7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 4om7 TOLL-LIKE RECEPTOR 6
(Homo
sapiens) 		3 / 3 TRP A 763
PHE A 773
TRP A 774
 None
 1.01A 1r15H-4om7A:
2.4		 1r15H-4om7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 4om7 TOLL-LIKE RECEPTOR 6
(Homo
sapiens) 		4 / 4 ASP A 652
LEU A 735
LEU A 702
LEU A 736
 None
 1.23A 1u18A-4om7A:
undetectable		 1u18A-4om7A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 4om7 TOLL-LIKE RECEPTOR 6
(Homo
sapiens) 		4 / 8 ASN A 690
LEU A 673
HIS A 674
ILE A 684
 None
 1.06A 4ok1A-4om7A:
undetectable		 4ok1A-4om7A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 4om7 TOLL-LIKE RECEPTOR 6
(Homo
sapiens) 		4 / 5 ILE A 777
ILE A 669
TYR A 663
GLU A 667
 None
 1.26A 4zzcE-4om7A:
undetectable		 4zzcE-4om7A:
20.43