SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4om9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ALA A 328
VAL A 326
TRP A 351
 None
 0.53A 1av2C-4om9A:
undetectable
1av2D-4om9A:
undetectable		 1av2C-4om9A:
1.65
1av2D-4om9A:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 GLN A  18
GLU A 426
ASP A  15
ARG A  11
 None
 1.14A 1dtlA-4om9A:
undetectable		 1dtlA-4om9A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ALA A 728
SER A 724
SER A 748
THR A 750
 None
 0.89A 1dvxA-4om9A:
undetectable		 1dvxA-4om9A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ASP A 432
GLN A 438
VAL A 481
GLY A 435
 None
 0.66A 1f5lA-4om9A:
15.2		 1f5lA-4om9A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 9 LEU A 311
ASP A 310
LEU A 309
ILE A 353
ILE A 341
 None
 1.28A 1hzeA-4om9A:
2.4
1hzeB-4om9A:
2.2		 1hzeA-4om9A:
6.89
1hzeB-4om9A:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 9 ILE A 341
LEU A 311
ASP A 310
LEU A 309
ILE A 353
 None
 1.28A 1hzeA-4om9A:
2.4
1hzeB-4om9A:
2.2		 1hzeA-4om9A:
6.89
1hzeB-4om9A:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 THR A 671
PHE A 651
GLU A 602
GLY A 603
 None
 1.34A 1icrA-4om9A:
undetectable
1icrB-4om9A:
undetectable		 1icrA-4om9A:
11.83
1icrB-4om9A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 THR A 671
PHE A 651
GLU A 602
GLY A 603
 None
 1.31A 1icvC-4om9A:
undetectable
1icvD-4om9A:
undetectable		 1icvC-4om9A:
11.83
1icvD-4om9A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ARG A 106
GLY A 315
ASP A 294
 None
 0.57A 1kf6A-4om9A:
undetectable
1kf6B-4om9A:
undetectable		 1kf6A-4om9A:
21.29
1kf6B-4om9A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 GLU A 602
GLY A 603
THR A 671
PHE A 651
 None
 1.32A 1kqbA-4om9A:
undetectable
1kqbB-4om9A:
undetectable		 1kqbA-4om9A:
13.42
1kqbB-4om9A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ALA A 328
VAL A 326
TRP A 351
 None
 0.85A 1nt6A-4om9A:
undetectable		 1nt6A-4om9A:
1.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ALA A 328
VAL A 326
TRP A 351
 None
 0.85A 1nt6B-4om9A:
undetectable		 1nt6B-4om9A:
1.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ASP A 499
HIS A 519
HIS A 474
 None
 0.68A 1oe1A-4om9A:
undetectable		 1oe1A-4om9A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 MET A  96
GLY A  99
THR A 250
ILE A 104
PHE A 102
 None
 1.36A 1p93D-4om9A:
undetectable		 1p93D-4om9A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 ASP A 501
HIS A 474
GLY A 500
HIS A 519
ASP A 522
 None
 1.38A 1t69A-4om9A:
undetectable		 1t69A-4om9A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.69A 1v54N-4om9A:
undetectable
1v54W-4om9A:
undetectable		 1v54N-4om9A:
19.71
1v54W-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ALA A 328
VAL A 326
TRP A 351
 None
 0.44A 1w5uC-4om9A:
undetectable
1w5uD-4om9A:
undetectable		 1w5uC-4om9A:
1.65
1w5uD-4om9A:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 GLY A 429
GLY A 428
GLY A 402
ASP A 432
ASN A 476
 None
 1.16A 1xdsB-4om9A:
undetectable		 1xdsB-4om9A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 SER A  27
GLU A 577
ASP A 447
 None
 0.88A 2avdB-4om9A:
undetectable		 2avdB-4om9A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 PHE A 316
VAL A 326
TRP A 351
 None
 0.86A 2cc8A-4om9A:
undetectable		 2cc8A-4om9A:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 PHE A 316
VAL A 326
TRP A 351
 None
 0.85A 2ccbA-4om9A:
undetectable		 2ccbA-4om9A:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.66A 2dyrN-4om9A:
undetectable
2dyrW-4om9A:
undetectable		 2dyrN-4om9A:
19.71
2dyrW-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.70A 2eijN-4om9A:
undetectable
2eijW-4om9A:
undetectable		 2eijN-4om9A:
19.71
2eijW-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.72A 2eikN-4om9A:
undetectable
2eikW-4om9A:
undetectable		 2eikN-4om9A:
19.71
2eikW-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.70A 2eilN-4om9A:
undetectable
2eilW-4om9A:
undetectable		 2eilN-4om9A:
19.71
2eilW-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 6 ASN A  73
ILE A 104
GLN A 105
THR A  54
 None
 1.26A 2hkkA-4om9A:
undetectable		 2hkkA-4om9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 TRP A 351
ALA A 328
VAL A 326
 None
 0.40A 2izqA-4om9A:
undetectable
2izqB-4om9A:
undetectable		 2izqA-4om9A:
1.65
2izqB-4om9A:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ARG A 495
SER A 592
TYR A 620
 None
 1.03A 2q2hA-4om9A:
undetectable
2q2hB-4om9A:
undetectable		 2q2hA-4om9A:
9.46
2q2hB-4om9A:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 GLY A 315
LEU A 369
VAL A 349
TYR A 324
SER A 347
 None
 1.24A 2vqyA-4om9A:
undetectable		 2vqyA-4om9A:
11.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 PHE A 316
VAL A 326
TRP A 351
 None
 0.83A 2vx9A-4om9A:
undetectable		 2vx9A-4om9A:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 HIS A 519
ILE A 621
HIS A 474
ASP A 499
 None
 1.06A 2xadA-4om9A:
undetectable		 2xadA-4om9A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 HIS A 519
ILE A 621
HIS A 474
ASP A 499
 None
 1.05A 2xadB-4om9A:
undetectable		 2xadB-4om9A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 HIS A 519
ILE A 621
HIS A 474
ASP A 499
 None
 1.06A 2xadC-4om9A:
undetectable		 2xadC-4om9A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 HIS A 519
ILE A 621
HIS A 474
ASP A 499
 None
 1.06A 2xadD-4om9A:
undetectable		 2xadD-4om9A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 11 SER A 455
LEU A 388
LEU A 414
LEU A 431
LYS A 430
 None
 1.11A 2xn5A-4om9A:
undetectable		 2xn5A-4om9A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ASP A 499
HIS A 519
HIS A 474
 None
 0.71A 2xxgC-4om9A:
undetectable		 2xxgC-4om9A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 LEU A 388
GLN A 375
THR A 393
THR A 385
 None
 1.08A 2zj0C-4om9A:
undetectable		 2zj0C-4om9A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.69A 3ablA-4om9A:
undetectable
3ablJ-4om9A:
undetectable		 3ablA-4om9A:
19.71
3ablJ-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.67A 3ag3N-4om9A:
undetectable
3ag3W-4om9A:
undetectable		 3ag3N-4om9A:
19.71
3ag3W-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.70A 3asnN-4om9A:
undetectable
3asnW-4om9A:
undetectable		 3asnN-4om9A:
19.71
3asnW-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ASP A 522
HIS A 519
TYR A 471
ILE A 443
 None
 0.63A 3avpA-4om9A:
undetectable		 3avpA-4om9A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 364
PHE A 336
PHE A 316
GLY A 367
 None
 1.10A 3em0B-4om9A:
undetectable		 3em0B-4om9A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 9 GLY A 382
VAL A 112
ILE A 397
VAL A 406
VAL A 386
 None
 1.09A 3fi0K-4om9A:
undetectable		 3fi0K-4om9A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 9 GLY A 382
VAL A 112
ILE A 397
VAL A 406
VAL A 386
 None
 1.10A 3fi0N-4om9A:
undetectable		 3fi0N-4om9A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_A_DX2A271_1
(PTERIDINE REDUCTASE
1)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 10 SER A 120
PHE A 121
TYR A 134
VAL A 212
PRO A 244
 None
 1.43A 3jq7A-4om9A:
0.0		 3jq7A-4om9A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ARG A 106
THR A  98
THR A 119
 None
 0.68A 3k2hB-4om9A:
undetectable		 3k2hB-4om9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ALA A 328
VAL A 326
TRP A 351
 None
 0.37A 3l8lA-4om9A:
undetectable
3l8lB-4om9A:
undetectable		 3l8lA-4om9A:
1.65
3l8lB-4om9A:
1.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ALA A 328
VAL A 326
TRP A 351
 None
 0.37A 3l8lC-4om9A:
undetectable
3l8lD-4om9A:
undetectable		 3l8lC-4om9A:
1.65
3l8lD-4om9A:
1.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 TYR A 790
LEU A 807
LEU A 801
THR A 735
 None
 1.01A 3lm8B-4om9A:
undetectable
3lm8D-4om9A:
undetectable		 3lm8B-4om9A:
12.03
3lm8D-4om9A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 6 ILE A  62
ALA A  67
THR A  69
THR A 227
 None
 1.10A 3mdrA-4om9A:
undetectable		 3mdrA-4om9A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 6 ILE A  62
ALA A  67
THR A  69
ALA A  58
 None
 0.94A 3mdrB-4om9A:
undetectable		 3mdrB-4om9A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 502
LEU A 483
THR A 451
ILE A 452
 None
 0.93A 3p50A-4om9A:
undetectable		 3p50A-4om9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 502
LEU A 483
THR A 451
ILE A 452
 None
 0.93A 3p50B-4om9A:
undetectable		 3p50B-4om9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 502
LEU A 483
THR A 451
ILE A 452
 None
 0.92A 3p50C-4om9A:
undetectable		 3p50C-4om9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 502
LEU A 483
THR A 451
ILE A 452
 None
 0.93A 3p50D-4om9A:
undetectable		 3p50D-4om9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 502
LEU A 483
THR A 451
ILE A 452
 None
 0.90A 3p50E-4om9A:
undetectable		 3p50E-4om9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 VAL A  70
HIS A  72
ASP A 101
GLY A 206
SER A 208
 None
 0.85A 3sufB-4om9A:
8.2		 3sufB-4om9A:
12.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 VAL A  70
HIS A  72
ASP A 101
GLY A 206
SER A 208
 None
 0.85A 3sufD-4om9A:
4.9		 3sufD-4om9A:
12.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 263
ILE A 275
LEU A 305
VAL A 326
 None
 0.81A 3ua5B-4om9A:
undetectable		 3ua5B-4om9A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 10 SER A 569
ALA A 520
ILE A 621
ILE A 640
ILE A 472
 None
 1.04A 4dt8B-4om9A:
undetectable		 4dt8B-4om9A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 10 SER A 569
ILE A 621
ILE A 640
ILE A 472
ASP A 499
 None
 1.03A 4dt8B-4om9A:
undetectable		 4dt8B-4om9A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 8 SER A 569
ILE A 621
ILE A 640
ILE A 472
ASP A 499
 None
 1.03A 4dtaB-4om9A:
undetectable		 4dtaB-4om9A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 HIS A  72
TYR A 166
GLY A 206
SER A 208
 None
 1.26A 4fu8A-4om9A:
15.0		 4fu8A-4om9A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 VAL A 349
GLY A 315
GLY A 338
ILE A 341
ILE A 317
 None
 0.95A 4iv0A-4om9A:
undetectable		 4iv0A-4om9A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 GLY A 384
GLY A 404
ILE A 364
ASP A 342
ILE A 343
 None
 1.01A 4iv0B-4om9A:
undetectable		 4iv0B-4om9A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 LEU A 311
GLY A 315
ILE A 270
LYS A 274
 None
 1.08A 4ma8C-4om9A:
undetectable		 4ma8C-4om9A:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 VAL A 349
GLY A 315
GLY A 338
ILE A 341
ILE A 317
 None
 1.00A 4mwzB-4om9A:
undetectable		 4mwzB-4om9A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 ASN A 587
ILE A 662
LEU A 678
GLY A 654
ILE A 605
 None
 1.19A 4o1eB-4om9A:
undetectable		 4o1eB-4om9A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 GLY A 475
LEU A 496
ILE A 502
LEU A 463
 None
 0.87A 4o8fA-4om9A:
undetectable		 4o8fA-4om9A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 10 THR A 446
ALA A 445
THR A 381
GLY A 401
GLY A 402
 None
 1.01A 4qvpK-4om9A:
undetectable
4qvpL-4om9A:
undetectable		 4qvpK-4om9A:
12.80
4qvpL-4om9A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 10 THR A 446
ALA A 445
THR A 381
GLY A 401
GLY A 402
 None
 1.01A 4qvpY-4om9A:
undetectable
4qvpZ-4om9A:
undetectable		 4qvpY-4om9A:
12.80
4qvpZ-4om9A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 303
PHE A 336
LEU A 309
LEU A 295
 None
 0.84A 4rmjA-4om9A:
undetectable		 4rmjA-4om9A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 ASN A  19
GLY A 116
ALA A 117
PHE A  50
VAL A  47
 None
 1.36A 4ryaA-4om9A:
undetectable		 4ryaA-4om9A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ALA A 759
SER A 755
ILE A 753
LEU A 816
 None
 0.98A 4uymA-4om9A:
undetectable		 4uymA-4om9A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 ASP A 169
VAL A 568
ASP A 522
GLY A 626
 None
 1.25A 4xp6A-4om9A:
undetectable		 4xp6A-4om9A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 11 ILE A 364
THR A 114
GLY A  63
ASP A 342
GLU A 366
 None
 1.22A 4xt7A-4om9A:
undetectable		 4xt7A-4om9A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 SER A 649
GLY A 665
ALA A 668
ILE A 646
 None
 0.67A 4yjiA-4om9A:
undetectable		 4yjiA-4om9A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.71A 5b1bA-4om9A:
undetectable
5b1bJ-4om9A:
undetectable		 5b1bA-4om9A:
19.71
5b1bJ-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 LEU A 171
GLY A  57
ALA A  58
SER A 210
 None
 0.72A 5f1aA-4om9A:
undetectable		 5f1aA-4om9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 LEU A 171
GLY A  57
ALA A  58
SER A 210
 None
 0.72A 5f1aB-4om9A:
undetectable		 5f1aB-4om9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 LEU A 225
ILE A 130
THR A 185
ALA A 183
LEU A 181
 None
 1.33A 5ienA-4om9A:
undetectable		 5ienA-4om9A:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.72A 5iy5A-4om9A:
undetectable
5iy5J-4om9A:
undetectable		 5iy5A-4om9A:
19.71
5iy5J-4om9A:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JDC_D_6JPD302_1
(PTERIDINE REDUCTASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 11 SER A 120
PHE A 121
TYR A 134
VAL A 212
PRO A 244
 None
 1.46A 5jdcA-4om9A:
undetectable
5jdcD-4om9A:
undetectable		 5jdcA-4om9A:
14.77
5jdcD-4om9A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 5 ILE A 343
LEU A 311
GLY A 315
PHE A 316
 None
 0.93A 5kmdC-4om9A:
undetectable
5kmdD-4om9A:
undetectable		 5kmdC-4om9A:
16.37
5kmdD-4om9A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 7 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.67A 5xdqA-4om9A:
undetectable
5xdqJ-4om9A:
undetectable		 5xdqA-4om9A:
19.71
5xdqJ-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.70A 5xdxN-4om9A:
undetectable
5xdxW-4om9A:
undetectable		 5xdxN-4om9A:
19.71
5xdxW-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.70A 5zcoA-4om9A:
undetectable
5zcoJ-4om9A:
undetectable		 5zcoA-4om9A:
19.71
5zcoJ-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 ILE A 662
LEU A 683
THR A 674
LEU A 672
 None
 0.74A 5zcqN-4om9A:
undetectable
5zcqW-4om9A:
undetectable		 5zcqN-4om9A:
19.71
5zcqW-4om9A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 ILE A 303
VAL A 326
PHE A 336
VAL A 296
PHE A 297
 None
 1.08A 6ap6A-4om9A:
undetectable		 6ap6A-4om9A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 ILE A 507
VAL A 601
LEU A 483
MET A 516
LEU A 498
 None
 1.23A 6b52A-4om9A:
undetectable		 6b52A-4om9A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 GLY A 713
THR A 715
GLU A 716
 None
 0.66A 6b58A-4om9A:
undetectable		 6b58A-4om9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 VAL A 477
GLY A 475
ALA A 445
GLU A 460
ASN A 437
 None
 1.18A 6bqgA-4om9A:
undetectable		 6bqgA-4om9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		4 / 8 GLY A 792
GLN A 791
SER A 814
PHE A 828
 None
 1.15A 6eqpA-4om9A:
undetectable		 6eqpA-4om9A:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		3 / 3 ASP A 196
ASP A  12
ASN A 555
 None
 0.77A 6gngB-4om9A:
undetectable		 6gngB-4om9A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 VAL A 864
VAL A 895
TRP A 933
PHE A 906
ASN A 873
 None
 1.45A 6iblA-4om9A:
undetectable		 6iblA-4om9A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4om9 SERINE PROTEASE PET
(Escherichia
coli) 		5 / 12 VAL A 864
VAL A 895
TRP A 933
PHE A 906
ASN A 873
 None
 1.40A 6iblB-4om9A:
undetectable		 6iblB-4om9A:
17.85