SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4omu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 11 GLY A 133
GLY A 102
LEU A 105
GLY A 128
LEU A 159
 None
 1.11A 1jg3A-4omuA:
5.2		 1jg3A-4omuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 11 GLY A 133
GLY A 102
LEU A 105
GLY A 129
LEU A 159
 None
 1.11A 1jg3A-4omuA:
5.2		 1jg3A-4omuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 11 GLY A 133
GLY A 102
LEU A 105
GLY A 128
LEU A 159
 None
 1.10A 1jg3B-4omuA:
5.8		 1jg3B-4omuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 11 ILE A 184
VAL A 181
ARG A 121
VAL A 115
ALA A 233
 None
 0.98A 1n4hA-4omuA:
undetectable		 1n4hA-4omuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 11 ALA A  81
GLY A  82
GLU A  65
ASN A  99
GLU A 136
 None
 1.41A 1n6cA-4omuA:
undetectable		 1n6cA-4omuA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 7 GLY A  97
GLY A  54
PHE A   7
PHE A  43
 None
 0.88A 2qwxA-4omuA:
5.3
2qwxB-4omuA:
undetectable		 2qwxA-4omuA:
24.67
2qwxB-4omuA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 PRO A 262
VAL A 263
GLU A 244
ALA A 243
 None
 0.86A 2v32A-4omuA:
undetectable
2v32B-4omuA:
undetectable		 2v32A-4omuA:
22.84
2v32B-4omuA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 PRO A 262
VAL A 263
GLU A 244
ALA A 243
 None
 0.91A 2v32A-4omuA:
undetectable
2v32B-4omuA:
undetectable		 2v32A-4omuA:
22.84
2v32B-4omuA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLY A 104
GLY A 102
ALA A 246
ALA A 243
LEU A 109
 None
 1.22A 3mteA-4omuA:
3.3		 3mteA-4omuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 HIS A  20
PHE A  23
ARG A 268
LEU A 242
GLN A 245
 None
 1.41A 4ac0A-4omuA:
undetectable		 4ac0A-4omuA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 ALA A  67
LEU A  95
ASP A 101
ASN A  99
TYR A  33
 None
 0.92A 4pclA-4omuA:
6.5		 4pclA-4omuA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 ARG A  77
GLY A  97
THR A  75
ASN A  85
 None
 1.03A 5hwaA-4omuA:
undetectable		 5hwaA-4omuA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 ALA A 127
VAL A 131
ILE A 138
VAL A 169
ALA A 156
 None
 1.20A 5nukA-4omuA:
undetectable		 5nukA-4omuA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 4omu SHIKIMATE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 LEU A 109
PHE A 223
ILE A 185
ALA A 187
GLY A 217
 None
 1.07A 5veuB-4omuA:
undetectable		 5veuB-4omuA:
18.88