SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4onf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	4onf	3D6 FAB ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 4	THR H 122 PRO H 124 THR H 123 PRO H 153	None	1.33A	1dsdC-4onfH: undetectable	1dsdC-4onfH: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	4onf	3D6 FAB ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 4	THR H 123 PRO H 153 THR H 122 PRO H 124	None	1.29A	1dsdC-4onfH: undetectable	1dsdC-4onfH: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	4onf	3D6 FAB ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 4	THR H 122 PRO H 124 THR H 123 PRO H 153	None	1.33A	1dsdC-4onfH: undetectable	1dsdC-4onfH: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	4onf	3D6 FAB ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 4	THR H 123 PRO H 153 THR H 122 PRO H 124	None	1.29A	1dsdC-4onfH: undetectable	1dsdC-4onfH: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4onf	3D6 FAB ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 7	ALA H 92 THR H 91 VAL H 115 GLU H 89	None	0.74A	5ecmD-4onfH: undetectable	5ecmD-4onfH: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4onf	3D6 FAB ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 7	ALA H 92 THR H 91 VAL H 115 GLU H 89	None	0.83A	5ecoD-4onfH: undetectable	5ecoD-4onfH: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA606_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	4onf	3D6 FAB ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 5	GLU H 154 PHE H 152 HIS H 205 THR H 116	None	1.07A	6b58A-4onfH: undetectable	6b58A-4onfH: 15.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","4onf","3D6 FAB ANTIBODY HEAVY CHAIN","Mus musculus",4,"THR H 122;PRO H 124;THR H 123;PRO H 153","None","1.33A","1dsdC-4onfH:undetectable","1dsdC-4onfH:12.90"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","4onf","3D6 FAB ANTIBODY HEAVY CHAIN","Mus musculus",4,"THR H 123;PRO H 153;THR H 122;PRO H 124","None","1.29A","1dsdC-4onfH:undetectable","1dsdC-4onfH:12.90"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","4onf","3D6 FAB ANTIBODY HEAVY CHAIN","Mus musculus",4,"THR H 122;PRO H 124;THR H 123;PRO H 153","None","1.33A","1dsdC-4onfH:undetectable","1dsdC-4onfH:12.90"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","4onf","3D6 FAB ANTIBODY HEAVY CHAIN","Mus musculus",4,"THR H 123;PRO H 153;THR H 122;PRO H 124","None","1.29A","1dsdC-4onfH:undetectable","1dsdC-4onfH:12.90"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","4onf","3D6 FAB ANTIBODY HEAVY CHAIN","Mus musculus",4,"ALA H  92;THR H  91;VAL H 115;GLU H  89","None","0.74A","5ecmD-4onfH:undetectable","5ecmD-4onfH:18.34"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","4onf","3D6 FAB ANTIBODY HEAVY CHAIN","Mus musculus",4,"ALA H  92;THR H  91;VAL H 115;GLU H  89","None","0.83A","5ecoD-4onfH:undetectable","5ecoD-4onfH:18.34"],["6B58_A_ACTA606_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","4onf","3D6 FAB ANTIBODY HEAVY CHAIN","Mus musculus",4,"GLU H 154;PHE H 152;HIS H 205;THR H 116","None","1.07A","6b58A-4onfH:undetectable","6b58A-4onfH:15.49"]]