SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4onz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		4 / 8 GLU A 347
GLY A 271
ASP A 364
THR A 343
 None
None
UNL  A 400 ( 3.0A)
UNL  A 400 ( 4.8A)
 0.77A 1m4iA-4onzA:
undetectable		 1m4iA-4onzA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		4 / 7 GLY A 114
TYR A 357
GLU A 116
SER A 111
 None
 1.03A 2ackA-4onzA:
undetectable		 2ackA-4onzA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		4 / 5 LEU A 239
ILE A 204
LEU A 205
ARG A 276
 None
 0.98A 2byoA-4onzA:
1.2		 2byoA-4onzA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 ASP A 237
ASN A 238
THR A 149
 None
 0.65A 2pymB-4onzA:
undetectable		 2pymB-4onzA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 GLY A 261
ASP A 295
SER A 265
 None
 0.64A 2qhfA-4onzA:
undetectable		 2qhfA-4onzA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		4 / 7 THR A 180
VAL A 170
THR A 172
VAL A 155
 None
 0.64A 3em0B-4onzA:
undetectable		 3em0B-4onzA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		5 / 12 ARG A 259
GLY A 294
ALA A 305
GLY A 306
ASN A 286
 None
 1.20A 3v3oA-4onzA:
undetectable		 3v3oA-4onzA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		5 / 10 VAL A  86
LEU A  88
LEU A 176
LYS A 177
VAL A 124
 None
 1.18A 4po0A-4onzA:
undetectable		 4po0A-4onzA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 ARG A  62
THR A 103
ASP A  93
 None
 0.97A 5g5gA-4onzA:
undetectable
5g5gB-4onzA:
undetectable		 5g5gA-4onzA:
17.86
5g5gB-4onzA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 SER A 201
SER A 203
PHE A 345
 None
None
UNL  A 400 ( 3.9A)
 0.88A 5mugA-4onzA:
undetectable		 5mugA-4onzA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 ASP A 143
ASN A  75
ASP A 364
 UNL  A 400 ( 3.0A)
UNL  A 400 ( 3.1A)
UNL  A 400 ( 3.0A)
 0.82A 5vopA-4onzA:
undetectable		 5vopA-4onzA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 ASP A 143
ASN A  75
ASP A 364
 UNL  A 400 ( 3.0A)
UNL  A 400 ( 3.1A)
UNL  A 400 ( 3.0A)
 0.85A 5vopB-4onzA:
undetectable		 5vopB-4onzA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4onz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
ovatus) 		4 / 7 ARG A 259
TYR A 285
LEU A 310
VAL A 318
 None
 1.18A 6g2pA-4onzA:
undetectable		 6g2pA-4onzA:
22.02