SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ope'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 4ope NRPS/PKS
(Streptomyces
albus) 		3 / 3 ALA A4764
VAL A4766
TRP A4765
 None
 0.91A 1bdwA-4opeA:
undetectable
1bdwB-4opeA:
undetectable		 1bdwA-4opeA:
2.28
1bdwB-4opeA:
2.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 0.69A 1d0vA-4opeA:
undetectable		 1d0vA-4opeA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 0.69A 1jhaA-4opeA:
undetectable		 1jhaA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.08A 1jhoA-4opeA:
undetectable		 1jhoA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.08A 1jhrA-4opeA:
undetectable		 1jhrA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.09A 1jhyA-4opeA:
undetectable		 1jhyA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.12A 1l4nA-4opeA:
undetectable		 1l4nA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.08A 1l5kA-4opeA:
undetectable		 1l5kA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.10A 1l5lA-4opeA:
undetectable		 1l5lA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.09A 1l5mA-4opeA:
undetectable		 1l5mA-4opeA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 GLY A4529
PRO A4537
GLY A4535
GLY A4451
GLY A4450
 None
 1.04A 1mxdA-4opeA:
undetectable		 1mxdA-4opeA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 11 GLY A4529
PRO A4537
GLY A4535
GLY A4451
GLY A4450
 None
 1.06A 1mxgA-4opeA:
undetectable		 1mxgA-4opeA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 HIS A4587
VAL A4562
VAL A4591
TYR A4235
GLN A4584
 None
 1.15A 1n2xA-4opeA:
undetectable		 1n2xA-4opeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 TYR A4346
ALA A4572
SER A4394
ALA A4576
HIS A4568
 None
 1.18A 1ve3A-4opeA:
undetectable		 1ve3A-4opeA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 6 ARG A4405
THR A4485
VAL A4648
LEU A4397
 None
 1.09A 2e1qA-4opeA:
undetectable		 2e1qA-4opeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 GLN A4302
ASP A4261
ALA A4305
PHE A4293
VAL A4290
 None
 1.45A 2g70B-4opeA:
undetectable		 2g70B-4opeA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 GLY A4419
GLY A4233
LEU A4578
THR A4391
LEU A4389
 None
 0.87A 2nyuB-4opeA:
undetectable		 2nyuB-4opeA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 7 ILE A4314
PRO A4259
GLY A4285
TRP A4286
 None
 1.14A 2pnjB-4opeA:
3.0		 2pnjB-4opeA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 PRO A4236
VAL A4255
GLU A4458
PRO A4259
 None
 0.95A 2v32C-4opeA:
undetectable
2v32D-4opeA:
undetectable		 2v32C-4opeA:
16.87
2v32D-4opeA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 PRO A4236
VAL A4255
GLU A4458
PRO A4259
 None
 0.94A 2v41C-4opeA:
undetectable
2v41D-4opeA:
undetectable		 2v41C-4opeA:
16.87
2v41D-4opeA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 7 LEU A4287
ALA A4457
ALA A4576
PHE A4244
 None
 0.99A 2vcvG-4opeA:
undetectable		 2vcvG-4opeA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 LEU A4397
ALA A4511
LEU A4507
PHE A4639
 None
 0.74A 2vcvP-4opeA:
undetectable		 2vcvP-4opeA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 4ope NRPS/PKS
(Streptomyces
albus) 		3 / 3 GLU A4225
SER A4653
VAL A4654
 None
 0.78A 3eeoA-4opeA:
undetectable		 3eeoA-4opeA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 4ope NRPS/PKS
(Streptomyces
albus) 		3 / 3 ASP A4289
SER A4292
ARG A4791
 None
 0.96A 3loqA-4opeA:
undetectable		 3loqA-4opeA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 6 GLU A4589
PRO A4618
ARG A4249
HIS A4587
 None
 1.28A 3ltwA-4opeA:
undetectable		 3ltwA-4opeA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 7 TYR A4429
TRP A4286
TYR A4454
CYH A4444
 None
 1.36A 3peoF-4opeA:
0.0		 3peoF-4opeA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 4 LEU A4479
LEU A4578
GLN A4588
GLU A4651
 None
 1.06A 4i41A-4opeA:
undetectable		 4i41A-4opeA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 9 THR A4530
GLY A4535
GLY A4448
PHE A4447
GLY A4451
 None
 1.09A 4kqiA-4opeA:
undetectable		 4kqiA-4opeA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 THR A4328
LEU A4333
VAL A4336
ASP A4476
 None
 1.07A 4l4bA-4opeA:
undetectable		 4l4bA-4opeA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 THR A4328
LEU A4333
VAL A4336
ASP A4476
 None
 1.12A 4l4dA-4opeA:
undetectable		 4l4dA-4opeA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 THR A4328
LEU A4333
VAL A4336
ASP A4476
 None
 1.16A 4l4fA-4opeA:
undetectable		 4l4fA-4opeA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 7 VAL A4482
ALA A4480
PHE A4585
TYR A4524
 None
 1.05A 4lb2A-4opeA:
undetectable		 4lb2A-4opeA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 CYH A4393
HIS A4528
THR A4530
HIS A4568
GLY A4640
 None
 0.64A 4ls7A-4opeA:
47.7		 4ls7A-4opeA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 CYH A4393
HIS A4528
THR A4530
HIS A4568
GLY A4640
 None
 0.62A 4ls7A-4opeA:
47.7
4ls7B-4opeA:
47.6		 4ls7A-4opeA:
22.89
4ls7B-4opeA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 11 ALA A4638
SER A4571
SER A4395
GLY A4574
THR A4530
 None
 1.28A 4mmaA-4opeA:
undetectable		 4mmaA-4opeA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 4 HIS A4401
ALA A4486
VAL A4487
GLU A4510
 None
 1.30A 4n6pA-4opeA:
undetectable		 4n6pA-4opeA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 4ope NRPS/PKS
(Streptomyces
albus) 		3 / 4 ARG A4252
GLY A4251
GLU A4250
 None
 0.63A 4z2dB-4opeA:
undetectable
4z2dC-4opeA:
undetectable		 4z2dB-4opeA:
20.80
4z2dC-4opeA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 5 ARG A4252
GLY A4251
GLU A4250
SER A4446
 None
 1.27A 4z3oA-4opeA:
undetectable
4z3oB-4opeA:
undetectable		 4z3oA-4opeA:
20.97
4z3oB-4opeA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 5 VAL A4416
VAL A4342
GLY A4343
PHE A4315
 None
 1.03A 5d4nA-4opeA:
undetectable
5d4nC-4opeA:
undetectable		 5d4nA-4opeA:
10.39
5d4nC-4opeA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 4 LEU A4543
ILE A4508
PRO A4519
LEU A4522
 None
 1.25A 5eb3A-4opeA:
undetectable		 5eb3A-4opeA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		3 / 3 ASN A4421
SER A4423
SER A4424
 None
 0.71A 5gsnA-4opeA:
undetectable		 5gsnA-4opeA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 6 LEU A4578
CYH A4404
HIS A4401
LEU A4400
 None
 1.19A 5hpuC-4opeA:
undetectable
5hpuD-4opeA:
undetectable		 5hpuC-4opeA:
6.86
5hpuD-4opeA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 8 ARG A4614
GLU A4597
GLY A4448
LEU A4599
 None
 0.91A 5sxqA-4opeA:
undetectable		 5sxqA-4opeA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 PHE A4447
PHE A4610
GLY A4535
HIS A4647
PHE A4547
 None
 1.19A 5v5zA-4opeA:
undetectable		 5v5zA-4opeA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 4ope NRPS/PKS
(Streptomyces
albus) 		4 / 4 VAL A4581
LEU A4582
LEU A4479
ASP A4325
 None
 1.20A 5xv7A-4opeA:
undetectable		 5xv7A-4opeA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 GLY A4640
ASN A4645
SER A4497
PHE A4639
TYR A4346
 None
 1.33A 5yf0A-4opeA:
undetectable		 5yf0A-4opeA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_B_SAMB503_0
(CARNOSINE
N-METHYLTRANSFERASE)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 GLY A4640
ASN A4645
SER A4497
PHE A4639
TYR A4346
 None
 1.31A 5yf0B-4opeA:
0.7		 5yf0B-4opeA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 4ope NRPS/PKS
(Streptomyces
albus) 		5 / 12 PHE A4297
ALA A4569
ALA A4576
THR A4579
LEU A4241
 None
 1.33A 6aycA-4opeA:
undetectable		 6aycA-4opeA:
9.63