SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4opm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 PRO A 300
THR A 261
PHE A 165
ASP A 168
 None
 1.19A 1p7lC-4opmA:
undetectable		 1p7lC-4opmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 PRO A 300
THR A 261
PHE A 165
ASP A 168
 None
 1.19A 1p7lD-4opmA:
undetectable		 1p7lD-4opmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 PRO A 300
THR A 261
PHE A 165
ASP A 168
 None
 1.21A 1rg9A-4opmA:
undetectable		 1rg9A-4opmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 PRO A 300
THR A 261
PHE A 165
ASP A 168
 None
 1.20A 1rg9B-4opmA:
undetectable		 1rg9B-4opmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 PRO A 300
THR A 261
PHE A 165
ASP A 168
 None
 1.20A 1rg9C-4opmA:
undetectable		 1rg9C-4opmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 PRO A 300
THR A 261
PHE A 165
ASP A 168
 None
 1.20A 1rg9D-4opmA:
undetectable		 1rg9D-4opmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 264
VAL A 167
ILE A 301
LEU A  71
LEU A  91
 None
 1.07A 1s19A-4opmA:
undetectable		 1s19A-4opmA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 238
LEU A 187
LEU A 234
ILE A 149
ILE A 272
 15P  A 401 ( 4.9A)
15P  A 401 ( 4.6A)
None
None
None
 1.23A 1tw4B-4opmA:
undetectable		 1tw4B-4opmA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 THR A 205
LEU A 201
VAL A 192
THR A 231
 15P  A 401 ( 4.5A)
None
None
None
 1.17A 1uyuB-4opmA:
undetectable		 1uyuB-4opmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 6 ALA A  88
TYR A 312
ILE A 309
LEU A  73
 None
 1.03A 1xvaA-4opmA:
undetectable
1xvaB-4opmA:
2.6		 1xvaA-4opmA:
24.05
1xvaB-4opmA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 9 GLY A  76
SER A 144
LEU A 145
LEU A 238
HIS A 298
 15P  A 401 ( 4.9A)
15P  A 401 (-3.6A)
15P  A 401 ( 4.9A)
15P  A 401 ( 4.9A)
None
 0.87A 1y7iA-4opmA:
19.4		 1y7iA-4opmA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 262
VAL A  87
ALA A  88
LEU A  71
ILE A  99
 None
 0.95A 2h42C-4opmA:
undetectable		 2h42C-4opmA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 264
VAL A  87
ALA A  88
LEU A  71
ILE A  99
 None
 1.11A 2h42C-4opmA:
undetectable		 2h42C-4opmA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 171
GLY A 146
LEU A  73
ILE A 301
VAL A 167
 15P  A 401 (-3.6A)
None
None
None
None
 0.86A 2oxtA-4opmA:
undetectable		 2oxtA-4opmA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 171
GLY A 146
LEU A  73
ILE A 301
VAL A 167
 15P  A 401 (-3.6A)
None
None
None
None
 0.87A 2oxtB-4opmA:
undetectable		 2oxtB-4opmA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  76
GLY A 147
SER A 148
LEU A 145
LEU A 166
 15P  A 401 ( 4.9A)
None
15P  A 401 ( 4.0A)
15P  A 401 ( 4.9A)
None
 1.15A 3e23A-4opmA:
2.7		 3e23A-4opmA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  72
ALA A 150
GLY A 155
ILE A 138
ILE A 140
 None
 0.88A 3ebzA-4opmA:
undetectable		 3ebzA-4opmA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  72
ALA A 150
GLY A 155
ILE A 138
ILE A 140
 None
 0.75A 3s53B-4opmA:
undetectable		 3s53B-4opmA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 6 GLY A 104
HIS A  75
SER A 105
THR A 108
 None
 1.14A 3tj7A-4opmA:
undetectable
3tj7B-4opmA:
undetectable		 3tj7A-4opmA:
22.01
3tj7B-4opmA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 6 GLY A 104
HIS A  75
SER A 105
THR A 108
 None
 1.09A 3tj7C-4opmA:
undetectable
3tj7D-4opmA:
undetectable		 3tj7C-4opmA:
22.01
3tj7D-4opmA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 6 HIS A  75
SER A 105
THR A 108
GLY A 104
 None
 1.08A 3tj7C-4opmA:
undetectable
3tj7D-4opmA:
undetectable		 3tj7C-4opmA:
22.01
3tj7D-4opmA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 ASP A 269
LEU A 166
ILE A 263
LEU A 280
ILE A 292
 None
 0.99A 4odrA-4opmA:
undetectable
4odrB-4opmA:
undetectable		 4odrA-4opmA:
15.43
4odrB-4opmA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		3 / 3 TYR A 116
GLY A 104
PRO A 103
 None
 0.74A 4qwpA-4opmA:
undetectable		 4qwpA-4opmA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 6 PHE A 173
SER A 144
HIS A 298
LEU A 181
 None
15P  A 401 (-3.6A)
None
None
 1.22A 5dzke-4opmA:
2.1
5dzks-4opmA:
undetectable		 5dzke-4opmA:
21.02
5dzks-4opmA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  72
ALA A 150
GLY A 155
ILE A 138
ILE A 140
 None
 0.72A 5e5jA-4opmA:
undetectable		 5e5jA-4opmA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  72
ALA A 150
GLY A 155
ILE A 138
ILE A 140
 None
 0.72A 5e5kB-4opmA:
undetectable		 5e5kB-4opmA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 PRO A 300
THR A 261
PHE A 165
ASP A 168
 None
 1.02A 5t8sB-4opmA:
undetectable		 5t8sB-4opmA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 7 THR A 205
PHE A 198
MET A 224
MET A 299
 15P  A 401 ( 4.5A)
15P  A 401 (-4.8A)
15P  A 401 ( 4.6A)
15P  A 401 ( 4.0A)
 1.05A 5u6mA-4opmA:
5.2		 5u6mA-4opmA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 5 HIS A  75
ALA A  78
SER A 105
GLY A 106
 None
 1.07A 5yodB-4opmA:
undetectable		 5yodB-4opmA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 5 HIS A  75
ALA A  78
SER A 105
GLY A 106
 None
 1.20A 5yodD-4opmA:
undetectable		 5yodD-4opmA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 9 ALA A 150
ILE A 149
GLY A 171
SER A 144
GLY A 142
 None
None
15P  A 401 (-3.6A)
15P  A 401 (-3.6A)
None
 1.34A 6awoA-4opmA:
undetectable		 6awoA-4opmA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 9 ALA A 150
ILE A 149
GLY A 171
SER A 144
GLY A 142
 None
None
15P  A 401 (-3.6A)
15P  A 401 (-3.6A)
None
 1.35A 6awqA-4opmA:
undetectable		 6awqA-4opmA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 7 VAL A 118
LEU A 262
PHE A 250
LEU A 280
 None
 1.20A 6aycA-4opmA:
undetectable		 6aycA-4opmA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4opm LIPASE
(Acinetobacter
baumannii) 		4 / 8 ILE A  36
THR A  35
GLN A  39
SER A  48
 None
 1.09A 6c06C-4opmA:
undetectable		 6c06C-4opmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 4opm LIPASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  72
ALA A 150
GLY A 155
ILE A 138
ILE A 140
 None
 0.69A 6dh3A-4opmA:
undetectable		 6dh3A-4opmA:
14.77