SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4opu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_N_TRPN81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 12 ALA A 20 ILE A 10 GLY A 290 SER A 307	FDA A 501 (-3.1A) None None None None	1.19A	1c9sN-4opuA: undetectable 1c9sO-4opuA: undetectable	1c9sN-4opuA: 11.00 1c9sO-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_Q_TRPQ81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 9	GLY A 12 ALA A 20 ILE A 10 GLY A 290 SER A 307	FDA A 501 (-3.1A) None None None None	1.18A	1c9sQ-4opuA: undetectable 1c9sR-4opuA: undetectable	1c9sQ-4opuA: 11.00 1c9sR-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_A_EAAA223_1 (GLUTATHIONE TRANSFERASE A1-1)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 8	PHE A 319 GLY A 28 ARG A 27 VAL A 114	None	1.16A	1gsfA-4opuA: undetectable	1gsfA-4opuA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_B_EAAB223_1 (GLUTATHIONE TRANSFERASE A1-1)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 8	PHE A 319 GLY A 28 ARG A 27 VAL A 114	None	1.16A	1gsfB-4opuA: undetectable	1gsfB-4opuA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_D_EAAD223_1 (GLUTATHIONE TRANSFERASE A1-1)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 8	PHE A 319 GLY A 28 ARG A 27 VAL A 114	None	1.16A	1gsfD-4opuA: undetectable	1gsfD-4opuA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_E_TRPE81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 9	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.15A	1gtfD-4opuA: undetectable 1gtfE-4opuA: undetectable	1gtfD-4opuA: 11.00 1gtfE-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_K_TRPK81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.13A	1gtfJ-4opuA: undetectable 1gtfK-4opuA: undetectable	1gtfJ-4opuA: 11.00 1gtfK-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_R_TRPR81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 9	GLY A 12 ALA A 20 ILE A 10 GLY A 290 SER A 307	FDA A 501 (-3.1A) None None None None	1.22A	1gtfR-4opuA: undetectable 1gtfS-4opuA: undetectable	1gtfR-4opuA: 11.00 1gtfS-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_F_TRPF81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 8	SER A 307 GLY A 12 ALA A 20 ILE A 10	None FDA A 501 (-3.1A) None None	0.78A	1gtnE-4opuA: undetectable 1gtnF-4opuA: undetectable	1gtnE-4opuA: 11.00 1gtnF-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L4N_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 9	GLY A 43 GLY A 17 PHE A 15 SER A 18 GLY A 12	FDA A 501 ( 4.9A) None None None FDA A 501 (-3.1A)	1.30A	1l4nA-4opuA: undetectable	1l4nA-4opuA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_E_TRPE81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 12 ALA A 20 ILE A 10 GLY A 290 SER A 307	FDA A 501 (-3.1A) None None None None	1.14A	1utdE-4opuA: undetectable 1utdF-4opuA: undetectable	1utdE-4opuA: 11.00 1utdF-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_H_TRPH81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 12 ALA A 20 ILE A 10 GLY A 290 SER A 307	FDA A 501 (-3.1A) None None None None	1.17A	1utdH-4opuA: undetectable 1utdI-4opuA: undetectable	1utdH-4opuA: 11.00 1utdI-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1436_1 (CHITINASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	3 / 3	ASP A 176 PHE A 291 ARG A 161	None	0.76A	2a3aA-4opuA: undetectable	2a3aA-4opuA: 22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYR_B_SVRB401_2 (NAD-DEPENDENT DEACETYLASE SIRTUIN-5)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 6	PHE A 205 GLN A 208 ASN A 359 LEU A 409	None	0.99A	2nyrA-4opuA: 3.9	2nyrA-4opuA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OA1_B_ADNB2005_1 (TRYPTOPHAN HALOGENASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 7	GLY A 234 GLY A 235 VAL A 269 ARG A 351	None None FDA A 501 ( 4.7A) None	0.76A	2oa1B-4opuA: 21.2	2oa1B-4opuA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_NCAA493_0 (CHORISMATE SYNTHASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 11	ALA A 20 ILE A 315 ILE A 286 ALA A 156 VAL A 8	None	1.12A	2qhfA-4opuA: undetectable	2qhfA-4opuA: 23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_C_ASDC1223_1 (GLUTATHIONE S-TRANSFERASE A2)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 8	GLY A 401 ARG A 402 LEU A 400 LEU A 406 PHE A 407	None	1.11A	2vctC-4opuA: undetectable	2vctC-4opuA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_D_ASDD1223_1 (GLUTATHIONE S-TRANSFERASE A2)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 7	GLY A 401 ARG A 402 LEU A 406 PHE A 407	None	0.90A	2vctD-4opuA: undetectable	2vctD-4opuA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_A_SAMA1248_0 (NON-STRUCTURAL PROTEIN 5)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	GLY A 308 GLY A 12 GLY A 14 SER A 19 THR A 121	None FDA A 501 (-3.1A) FDA A 501 (-3.2A) None FDA A 501 (-4.0A)	0.81A	2wa2A-4opuA: 3.1	2wa2A-4opuA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_A_SAMA1248_0 (NON-STRUCTURAL PROTEIN 5)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	GLY A 308 GLY A 12 SER A 19 THR A 121 ILE A 11	None FDA A 501 (-3.1A) None FDA A 501 (-4.0A) None	1.21A	2wa2A-4opuA: 3.1	2wa2A-4opuA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EEY_C_SAMC300_1 (PUTATIVE RRNA METHYLASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	3 / 3	ASN A 294 ASP A 183 GLN A 233	GRG A 503 (-4.6A) GRG A 502 (-3.4A) None	0.77A	3eeyC-4opuA: 3.0	3eeyC-4opuA: 18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EEY_D_SAMD300_1 (PUTATIVE RRNA METHYLASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	3 / 3	ASN A 294 ASP A 183 GLN A 233	GRG A 503 (-4.6A) GRG A 502 (-3.4A) None	0.80A	3eeyD-4opuA: 2.9	3eeyD-4opuA: 18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EEY_E_SAME300_1 (PUTATIVE RRNA METHYLASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	3 / 3	ASN A 294 ASP A 183 GLN A 233	GRG A 503 (-4.6A) GRG A 502 (-3.4A) None	0.78A	3eeyE-4opuA: 3.2	3eeyE-4opuA: 18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_A_SAMA301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	PHE A 163 GLY A 12 SER A 36 ASP A 118 ILE A 116	None FDA A 501 (-3.1A) FDA A 501 (-3.1A) None None	1.22A	3iv6A-4opuA: 2.5	3iv6A-4opuA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_C_SAMC301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	PHE A 163 GLY A 12 SER A 36 ASP A 118 ILE A 116	None FDA A 501 (-3.1A) FDA A 501 (-3.1A) None None	1.19A	3iv6C-4opuA: 2.5	3iv6C-4opuA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IXL_A_PACA5000_0 (ARYLMALONATE DECARBOXYLASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	SER A 307 TYR A 336 SER A 303 GLY A 302 GLY A 300	None None None None FDA A 501 (-3.2A)	1.31A	3ixlA-4opuA: undetectable	3ixlA-4opuA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K2H_B_LYAB513_1 (DIHYDROFOLATE REDUCTASE/THYMIDYLAT E SYNTHASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	ALA A 304 SER A 307 LEU A 9 ASP A 35 GLY A 13	FDA A 501 ( 4.1A) None None FDA A 501 (-2.5A) FDA A 501 ( 4.9A)	1.12A	3k2hB-4opuA: undetectable	3k2hB-4opuA: 22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPB_D_SAMD1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	ILE A 11 THR A 157 VAL A 153 ILE A 283 SER A 165	None FDA A 501 (-3.8A) None None None	1.33A	3kpbD-4opuA: undetectable	3kpbD-4opuA: 15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NU9_A_478A401_2 (PROTEASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 231 ALA A 185 GLY A 48 VAL A 293 VAL A 269	GRG A 502 (-3.5A) FDA A 501 (-3.5A) FDA A 501 (-3.2A) FDA A 501 (-4.7A) FDA A 501 ( 4.7A)	1.06A	3nu9B-4opuA: undetectable	3nu9B-4opuA: 12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_B_SAMB300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	3 / 3	TYR A 215 ASP A 183 ASP A 181	GRG A 503 ( 4.1A) GRG A 502 (-3.4A) None	0.93A	3ou6B-4opuA: 2.3	3ou6B-4opuA: 19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_D_9PLD1_1 (CYTOCHROME P450 2A13)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 8	PHE A 353 PHE A 350 ALA A 413 ALA A 393	None	0.91A	3t3sD-4opuA: undetectable	3t3sD-4opuA: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_B_CLMB221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	THR A 157 SER A 162 LEU A 9 VAL A 148 VAL A 34	FDA A 501 (-3.8A) FDA A 501 (-2.9A) None None None	1.23A	3u9fB-4opuA: undetectable 3u9fC-4opuA: undetectable	3u9fB-4opuA: 17.65 3u9fC-4opuA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_E_CLME221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	THR A 157 SER A 162 LEU A 9 VAL A 148 VAL A 34	FDA A 501 (-3.8A) FDA A 501 (-2.9A) None None None	1.29A	3u9fE-4opuA: undetectable	3u9fE-4opuA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_H_CLMH221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	THR A 157 SER A 162 LEU A 9 VAL A 148 VAL A 34	FDA A 501 (-3.8A) FDA A 501 (-2.9A) None None None	1.26A	3u9fH-4opuA: undetectable 3u9fI-4opuA: undetectable	3u9fH-4opuA: 17.65 3u9fI-4opuA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_I_CLMI221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	THR A 157 SER A 162 LEU A 9 VAL A 148 VAL A 34	FDA A 501 (-3.8A) FDA A 501 (-2.9A) None None None	1.27A	3u9fI-4opuA: undetectable	3u9fI-4opuA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_J_CLMJ221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	THR A 157 SER A 162 LEU A 9 VAL A 148 VAL A 34	FDA A 501 (-3.8A) FDA A 501 (-2.9A) None None None	1.25A	3u9fJ-4opuA: undetectable 3u9fK-4opuA: undetectable	3u9fJ-4opuA: 17.65 3u9fK-4opuA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_N_CLMN221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 11	THR A 157 SER A 162 LEU A 9 VAL A 148 VAL A 34	FDA A 501 (-3.8A) FDA A 501 (-2.9A) None None None	1.20A	3u9fN-4opuA: undetectable 3u9fO-4opuA: undetectable	3u9fN-4opuA: 17.65 3u9fO-4opuA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_P_CLMP221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 9	THR A 157 SER A 162 LEU A 9 VAL A 148 VAL A 34	FDA A 501 (-3.8A) FDA A 501 (-2.9A) None None None	1.27A	3u9fP-4opuA: undetectable	3u9fP-4opuA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	GLY A 12 GLY A 13 ASN A 102 ILE A 10 ILE A 116	FDA A 501 (-3.1A) FDA A 501 ( 4.9A) None None None	1.26A	4fglA-4opuA: undetectable 4fglB-4opuA: undetectable	4fglA-4opuA: 20.61 4fglB-4opuA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_A_SAMA301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	GLY A 17 LEU A 24 ALA A 311 VAL A 154 VAL A 152	None	0.97A	4htfA-4opuA: 2.8	4htfA-4opuA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L6V_A_PQNA2001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 9	PHE A 324 ALA A 314 LEU A 329 GLY A 328 ALA A 122	None None None None FDA A 501 (-4.0A)	1.45A	4l6va-4opuA: undetectable 4l6vf-4opuA: undetectable	4l6va-4opuA: 19.66 4l6vf-4opuA: 13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBQ_A_ACTA605_0 (SERUM ALBUMIN)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 6	TYR A 340 HIS A 297 GLY A 300 ASN A 294	GRG A 503 (-4.5A) GRG A 502 ( 4.1A) FDA A 501 (-3.2A) GRG A 503 (-4.6A)	1.10A	4zbqA-4opuA: 2.3	4zbqA-4opuA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A5Z_C_WJZC304_0 (BETA-LACTAMASE NDM-1)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 7	HIS A 297 GLY A 300 ASN A 294 HIS A 55	GRG A 502 ( 4.1A) FDA A 501 (-3.2A) GRG A 503 (-4.6A) GRG A 503 (-3.4A)	1.32A	5a5zC-4opuA: undetectable	5a5zC-4opuA: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.14A	5eevA-4opuA: undetectable 5eevB-4opuA: undetectable	5eevA-4opuA: 11.00 5eevB-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.14A	5eewA-4opuA: undetectable 5eewB-4opuA: undetectable	5eewA-4opuA: 11.00 5eewB-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEX_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.14A	5eexA-4opuA: undetectable 5eexB-4opuA: undetectable	5eexA-4opuA: 11.00 5eexB-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEY_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.14A	5eeyA-4opuA: undetectable 5eeyB-4opuA: undetectable	5eeyA-4opuA: 11.00 5eeyB-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.14A	5eezA-4opuA: undetectable 5eezB-4opuA: undetectable	5eezA-4opuA: 11.00 5eezB-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF0_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.13A	5ef0A-4opuA: undetectable 5ef0B-4opuA: undetectable	5ef0A-4opuA: 11.00 5ef0B-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.13A	5ef1A-4opuA: undetectable 5ef1B-4opuA: undetectable	5ef1A-4opuA: 11.00 5ef1B-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.13A	5ef2A-4opuA: undetectable 5ef2B-4opuA: undetectable	5ef2A-4opuA: 11.00 5ef2B-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 10	GLY A 290 SER A 307 GLY A 12 ALA A 20 ILE A 10	None None FDA A 501 (-3.1A) None None	1.13A	5ef3A-4opuA: undetectable 5ef3B-4opuA: undetectable	5ef3A-4opuA: 11.00 5ef3B-4opuA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I73_A_68PA705_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 9	ALA A 345 GLN A 344 LEU A 444 ILE A 419 PHE A 447	None	1.49A	5i73A-4opuA: undetectable	5i73A-4opuA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ERYA404_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	ILE A 10 THR A 292 PHE A 163 ALA A 122 ILE A 42	None None None FDA A 501 (-4.0A) None	1.44A	5iwuA-4opuA: undetectable	5iwuA-4opuA: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JVZ_B_FLPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	5 / 12	VAL A 296 LEU A 347 LEU A 354 ALA A 379 LEU A 376	GRG A 502 ( 4.7A) None GRG A 503 ( 4.1A) None GRG A 503 ( 4.8A)	1.12A	5jvzB-4opuA: undetectable	5jvzB-4opuA: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	4opu	CONSERVED ARCHAEAL PROTEIN (Sulfolobus acidocaldarius)	4 / 7	PHE A 350 ARG A 351 LEU A 347 ALA A 379	None	1.20A	6b89A-4opuA: 1.0	6b89A-4opuA: 11.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C9S_N_TRPN81_0","TRP RNA-BINDING ATTENUATION PROTEIN","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  12;ALA A  20;ILE A  10;GLY A 290;SER A 307","FDA A 501 (-3.1A);None;None;None;None","1.19A","1c9sN-4opuA:undetectable;1c9sO-4opuA:undetectable","1c9sN-4opuA:11.00;1c9sO-4opuA:11.00"],["1C9S_Q_TRPQ81_0","TRP RNA-BINDING ATTENUATION PROTEIN","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  12;ALA A  20;ILE A  10;GLY A 290;SER A 307","FDA A 501 (-3.1A);None;None;None;None","1.18A","1c9sQ-4opuA:undetectable;1c9sR-4opuA:undetectable","1c9sQ-4opuA:11.00;1c9sR-4opuA:11.00"],["1GSF_A_EAAA223_1","GLUTATHIONE TRANSFERASE A1-1","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"PHE A 319;GLY A  28;ARG A  27;VAL A 114","None","1.16A","1gsfA-4opuA:undetectable","1gsfA-4opuA:19.57"],["1GSF_B_EAAB223_1","GLUTATHIONE TRANSFERASE A1-1","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"PHE A 319;GLY A  28;ARG A  27;VAL A 114","None","1.16A","1gsfB-4opuA:undetectable","1gsfB-4opuA:19.57"],["1GSF_D_EAAD223_1","GLUTATHIONE TRANSFERASE A1-1","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"PHE A 319;GLY A  28;ARG A  27;VAL A 114","None","1.16A","1gsfD-4opuA:undetectable","1gsfD-4opuA:19.57"],["1GTF_E_TRPE81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.15A","1gtfD-4opuA:undetectable;1gtfE-4opuA:undetectable","1gtfD-4opuA:11.00;1gtfE-4opuA:11.00"],["1GTF_K_TRPK81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.13A","1gtfJ-4opuA:undetectable;1gtfK-4opuA:undetectable","1gtfJ-4opuA:11.00;1gtfK-4opuA:11.00"],["1GTF_R_TRPR81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  12;ALA A  20;ILE A  10;GLY A 290;SER A 307","FDA A 501 (-3.1A);None;None;None;None","1.22A","1gtfR-4opuA:undetectable;1gtfS-4opuA:undetectable","1gtfR-4opuA:11.00;1gtfS-4opuA:11.00"],["1GTN_F_TRPF81_0","TRP RNA-BINDING ATTENUATION PROTEIN","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"SER A 307;GLY A  12;ALA A  20;ILE A  10","None;FDA A 501 (-3.1A);None;None","0.78A","1gtnE-4opuA:undetectable;1gtnF-4opuA:undetectable","1gtnE-4opuA:11.00;1gtnF-4opuA:11.00"],["1L4N_A_NIOA991_1","NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  43;GLY A  17;PHE A  15;SER A  18;GLY A  12","FDA A 501 ( 4.9A);None;None;None;FDA A 501 (-3.1A)","1.30A","1l4nA-4opuA:undetectable","1l4nA-4opuA:23.40"],["1UTD_E_TRPE81_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  12;ALA A  20;ILE A  10;GLY A 290;SER A 307","FDA A 501 (-3.1A);None;None;None;None","1.14A","1utdE-4opuA:undetectable;1utdF-4opuA:undetectable","1utdE-4opuA:11.00;1utdF-4opuA:11.00"],["1UTD_H_TRPH81_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  12;ALA A  20;ILE A  10;GLY A 290;SER A 307","FDA A 501 (-3.1A);None;None;None;None","1.17A","1utdH-4opuA:undetectable;1utdI-4opuA:undetectable","1utdH-4opuA:11.00;1utdI-4opuA:11.00"],["2A3A_A_TEPA1436_1","CHITINASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",3,"ASP A 176;PHE A 291;ARG A 161","None","0.76A","2a3aA-4opuA:undetectable","2a3aA-4opuA:22.94"],["2NYR_B_SVRB401_2","NAD-DEPENDENT DEACETYLASE SIRTUIN-5;NAD-DEPENDENT DEACETYLASE SIRTUIN-5","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"PHE A 205;GLN A 208;ASN A 359;LEU A 409","None","0.99A","2nyrA-4opuA:3.9","2nyrA-4opuA:20.63"],["2OA1_B_ADNB2005_1","TRYPTOPHAN HALOGENASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"GLY A 234;GLY A 235;VAL A 269;ARG A 351","None;None;FDA A 501 ( 4.7A);None","0.76A","2oa1B-4opuA:21.2","2oa1B-4opuA:23.49"],["2QHF_A_NCAA493_0","CHORISMATE SYNTHASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"ALA A  20;ILE A 315;ILE A 286;ALA A 156;VAL A   8","None","1.12A","2qhfA-4opuA:undetectable","2qhfA-4opuA:23.69"],["2VCT_C_ASDC1223_1","GLUTATHIONE S-TRANSFERASE A2","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 401;ARG A 402;LEU A 400;LEU A 406;PHE A 407","None","1.11A","2vctC-4opuA:undetectable","2vctC-4opuA:18.32"],["2VCT_D_ASDD1223_1","GLUTATHIONE S-TRANSFERASE A2","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"GLY A 401;ARG A 402;LEU A 406;PHE A 407","None","0.90A","2vctD-4opuA:undetectable","2vctD-4opuA:18.32"],["2WA2_A_SAMA1248_0","NON-STRUCTURAL PROTEIN 5","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 308;GLY A  12;GLY A  14;SER A  19;THR A 121","None;FDA A 501 (-3.1A);FDA A 501 (-3.2A);None;FDA A 501 (-4.0A)","0.81A","2wa2A-4opuA:3.1","2wa2A-4opuA:19.56"],["2WA2_A_SAMA1248_0","NON-STRUCTURAL PROTEIN 5","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 308;GLY A  12;SER A  19;THR A 121;ILE A  11","None;FDA A 501 (-3.1A);None;FDA A 501 (-4.0A);None","1.21A","2wa2A-4opuA:3.1","2wa2A-4opuA:19.56"],["3EEY_C_SAMC300_1","PUTATIVE RRNA METHYLASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",3,"ASN A 294;ASP A 183;GLN A 233","GRG A 503 (-4.6A);GRG A 502 (-3.4A);None","0.77A","3eeyC-4opuA:3.0","3eeyC-4opuA:18.54"],["3EEY_D_SAMD300_1","PUTATIVE RRNA METHYLASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",3,"ASN A 294;ASP A 183;GLN A 233","GRG A 503 (-4.6A);GRG A 502 (-3.4A);None","0.80A","3eeyD-4opuA:2.9","3eeyD-4opuA:18.54"],["3EEY_E_SAME300_1","PUTATIVE RRNA METHYLASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",3,"ASN A 294;ASP A 183;GLN A 233","GRG A 503 (-4.6A);GRG A 502 (-3.4A);None","0.78A","3eeyE-4opuA:3.2","3eeyE-4opuA:18.54"],["3IV6_A_SAMA301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"PHE A 163;GLY A  12;SER A  36;ASP A 118;ILE A 116","None;FDA A 501 (-3.1A);FDA A 501 (-3.1A);None;None","1.22A","3iv6A-4opuA:2.5","3iv6A-4opuA:22.13"],["3IV6_C_SAMC301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"PHE A 163;GLY A  12;SER A  36;ASP A 118;ILE A 116","None;FDA A 501 (-3.1A);FDA A 501 (-3.1A);None;None","1.19A","3iv6C-4opuA:2.5","3iv6C-4opuA:22.13"],["3IXL_A_PACA5000_0","ARYLMALONATE DECARBOXYLASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"SER A 307;TYR A 336;SER A 303;GLY A 302;GLY A 300","None;None;None;None;FDA A 501 (-3.2A)","1.31A","3ixlA-4opuA:undetectable","3ixlA-4opuA:20.70"],["3K2H_B_LYAB513_1","DIHYDROFOLATE REDUCTASE\/THYMIDYLATE SYNTHASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"ALA A 304;SER A 307;LEU A   9;ASP A  35;GLY A  13","FDA A 501 ( 4.1A);None;None;FDA A 501 (-2.5A);FDA A 501 ( 4.9A)","1.12A","3k2hB-4opuA:undetectable","3k2hB-4opuA:22.26"],["3KPB_D_SAMD1000_0","UNCHARACTERIZED PROTEIN MJ0100","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"ILE A  11;THR A 157;VAL A 153;ILE A 283;SER A 165","None;FDA A 501 (-3.8A);None;None;None","1.33A","3kpbD-4opuA:undetectable","3kpbD-4opuA:15.72"],["3NU9_A_478A401_2","PROTEASE;PROTEASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 231;ALA A 185;GLY A  48;VAL A 293;VAL A 269","GRG A 502 (-3.5A);FDA A 501 (-3.5A);FDA A 501 (-3.2A);FDA A 501 (-4.7A);FDA A 501 ( 4.7A)","1.06A","3nu9B-4opuA:undetectable","3nu9B-4opuA:12.95"],["3OU6_B_SAMB300_1","SAM-DEPENDENT METHYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",3,"TYR A 215;ASP A 183;ASP A 181","GRG A 503 ( 4.1A);GRG A 502 (-3.4A);None","0.93A","3ou6B-4opuA:2.3","3ou6B-4opuA:19.03"],["3T3S_D_9PLD1_1","CYTOCHROME P450 2A13","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"PHE A 353;PHE A 350;ALA A 413;ALA A 393","None","0.91A","3t3sD-4opuA:undetectable","3t3sD-4opuA:21.76"],["3U9F_B_CLMB221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"THR A 157;SER A 162;LEU A   9;VAL A 148;VAL A  34","FDA A 501 (-3.8A);FDA A 501 (-2.9A);None;None;None","1.23A","3u9fB-4opuA:undetectable;3u9fC-4opuA:undetectable","3u9fB-4opuA:17.65;3u9fC-4opuA:17.65"],["3U9F_E_CLME221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"THR A 157;SER A 162;LEU A   9;VAL A 148;VAL A  34","FDA A 501 (-3.8A);FDA A 501 (-2.9A);None;None;None","1.29A","3u9fE-4opuA:undetectable","3u9fE-4opuA:17.65"],["3U9F_H_CLMH221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"THR A 157;SER A 162;LEU A   9;VAL A 148;VAL A  34","FDA A 501 (-3.8A);FDA A 501 (-2.9A);None;None;None","1.26A","3u9fH-4opuA:undetectable;3u9fI-4opuA:undetectable","3u9fH-4opuA:17.65;3u9fI-4opuA:17.65"],["3U9F_I_CLMI221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"THR A 157;SER A 162;LEU A   9;VAL A 148;VAL A  34","FDA A 501 (-3.8A);FDA A 501 (-2.9A);None;None;None","1.27A","3u9fI-4opuA:undetectable","3u9fI-4opuA:17.65"],["3U9F_J_CLMJ221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"THR A 157;SER A 162;LEU A   9;VAL A 148;VAL A  34","FDA A 501 (-3.8A);FDA A 501 (-2.9A);None;None;None","1.25A","3u9fJ-4opuA:undetectable;3u9fK-4opuA:undetectable","3u9fJ-4opuA:17.65;3u9fK-4opuA:17.65"],["3U9F_N_CLMN221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"THR A 157;SER A 162;LEU A   9;VAL A 148;VAL A  34","FDA A 501 (-3.8A);FDA A 501 (-2.9A);None;None;None","1.20A","3u9fN-4opuA:undetectable;3u9fO-4opuA:undetectable","3u9fN-4opuA:17.65;3u9fO-4opuA:17.65"],["3U9F_P_CLMP221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"THR A 157;SER A 162;LEU A   9;VAL A 148;VAL A  34","FDA A 501 (-3.8A);FDA A 501 (-2.9A);None;None;None","1.27A","3u9fP-4opuA:undetectable","3u9fP-4opuA:17.65"],["4FGL_A_CLQA303_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  12;GLY A  13;ASN A 102;ILE A  10;ILE A 116","FDA A 501 (-3.1A);FDA A 501 ( 4.9A);None;None;None","1.26A","4fglA-4opuA:undetectable;4fglB-4opuA:undetectable","4fglA-4opuA:20.61;4fglB-4opuA:20.61"],["4HTF_A_SAMA301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A  17;LEU A  24;ALA A 311;VAL A 154;VAL A 152","None","0.97A","4htfA-4opuA:2.8","4htfA-4opuA:20.27"],["4L6V_A_PQNA2001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"PHE A 324;ALA A 314;LEU A 329;GLY A 328;ALA A 122","None;None;None;None;FDA A 501 (-4.0A)","1.45A","4l6va-4opuA:undetectable;4l6vf-4opuA:undetectable","4l6va-4opuA:19.66;4l6vf-4opuA:13.96"],["4ZBQ_A_ACTA605_0","SERUM ALBUMIN","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"TYR A 340;HIS A 297;GLY A 300;ASN A 294","GRG A 503 (-4.5A);GRG A 502 ( 4.1A);FDA A 501 (-3.2A);GRG A 503 (-4.6A)","1.10A","4zbqA-4opuA:2.3","4zbqA-4opuA:21.56"],["5A5Z_C_WJZC304_0","BETA-LACTAMASE NDM-1","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"HIS A 297;GLY A 300;ASN A 294;HIS A  55","GRG A 502 ( 4.1A);FDA A 501 (-3.2A);GRG A 503 (-4.6A);GRG A 503 (-3.4A)","1.32A","5a5zC-4opuA:undetectable","5a5zC-4opuA:19.47"],["5EEV_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.14A","5eevA-4opuA:undetectable;5eevB-4opuA:undetectable","5eevA-4opuA:11.00;5eevB-4opuA:11.00"],["5EEW_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.14A","5eewA-4opuA:undetectable;5eewB-4opuA:undetectable","5eewA-4opuA:11.00;5eewB-4opuA:11.00"],["5EEX_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.14A","5eexA-4opuA:undetectable;5eexB-4opuA:undetectable","5eexA-4opuA:11.00;5eexB-4opuA:11.00"],["5EEY_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.14A","5eeyA-4opuA:undetectable;5eeyB-4opuA:undetectable","5eeyA-4opuA:11.00;5eeyB-4opuA:11.00"],["5EEZ_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.14A","5eezA-4opuA:undetectable;5eezB-4opuA:undetectable","5eezA-4opuA:11.00;5eezB-4opuA:11.00"],["5EF0_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.13A","5ef0A-4opuA:undetectable;5ef0B-4opuA:undetectable","5ef0A-4opuA:11.00;5ef0B-4opuA:11.00"],["5EF1_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.13A","5ef1A-4opuA:undetectable;5ef1B-4opuA:undetectable","5ef1A-4opuA:11.00;5ef1B-4opuA:11.00"],["5EF2_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.13A","5ef2A-4opuA:undetectable;5ef2B-4opuA:undetectable","5ef2A-4opuA:11.00;5ef2B-4opuA:11.00"],["5EF3_A_TRPA101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"GLY A 290;SER A 307;GLY A  12;ALA A  20;ILE A  10","None;None;FDA A 501 (-3.1A);None;None","1.13A","5ef3A-4opuA:undetectable;5ef3B-4opuA:undetectable","5ef3A-4opuA:11.00;5ef3B-4opuA:11.00"],["5I73_A_68PA705_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"ALA A 345;GLN A 344;LEU A 444;ILE A 419;PHE A 447","None","1.49A","5i73A-4opuA:undetectable","5i73A-4opuA:21.50"],["5IWU_A_ERYA404_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"ILE A  10;THR A 292;PHE A 163;ALA A 122;ILE A  42","None;None;None;FDA A 501 (-4.0A);None","1.44A","5iwuA-4opuA:undetectable","5iwuA-4opuA:23.06"],["5JVZ_B_FLPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",5,"VAL A 296;LEU A 347;LEU A 354;ALA A 379;LEU A 376","GRG A 502 ( 4.7A);None;GRG A 503 ( 4.1A);None;GRG A 503 ( 4.8A)","1.12A","5jvzB-4opuA:undetectable","5jvzB-4opuA:21.92"],["6B89_B_NOVB403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","4opu","CONSERVED ARCHAEAL PROTEIN","Sulfolobus acidocaldarius",4,"PHE A 350;ARG A 351;LEU A 347;ALA A 379","None","1.20A","6b89A-4opuA:1.0","6b89A-4opuA:11.27"]]