SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
4 / 8 ALA A 278
HIS A 304
THR A 305
ILE A 287
None
0.71A 1c9sI-4oqqA:
undetectable
1c9sJ-4oqqA:
undetectable
1c9sI-4oqqA:
14.63
1c9sJ-4oqqA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
4 / 8 ALA A 278
HIS A 304
THR A 305
ILE A 287
None
0.75A 1c9sU-4oqqA:
undetectable
1c9sV-4oqqA:
undetectable
1c9sU-4oqqA:
14.63
1c9sV-4oqqA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
4 / 6 LEU A 291
GLY A 293
LYS A  71
TYR A  72
None
1.25A 1gtiC-4oqqA:
undetectable
1gtiC-4oqqA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
4 / 5 LEU A 291
GLY A 293
LYS A  71
TYR A  72
None
1.25A 1gtiF-4oqqA:
undetectable
1gtiF-4oqqA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
4 / 8 ALA A 278
HIS A 304
THR A 305
ILE A 287
None
0.68A 1utdI-4oqqA:
undetectable
1utdJ-4oqqA:
undetectable
1utdI-4oqqA:
14.63
1utdJ-4oqqA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 ALA A 216
PHE A 224
THR A 260
VAL A 175
GLY A 143
None
1.28A 2ve3B-4oqqA:
undetectable
2ve3B-4oqqA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 GLY A 113
ILE A 111
ASP A 110
VAL A 106
GLY A 199
None
1.00A 3bwcA-4oqqA:
undetectable
3bwcA-4oqqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 GLY A 113
ILE A 111
ASP A 110
VAL A 106
GLY A 199
None
1.00A 3bwcB-4oqqA:
2.9
3bwcB-4oqqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
3 / 3 HIS A  78
SER A  66
GLU A  69
None
0.88A 3s8pA-4oqqA:
undetectable
3s8pA-4oqqA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 9 ILE A 144
GLY A 143
THR A 151
GLY A 117
ARG A 282
None
None
None
BCN  A 401 (-3.2A)
BCN  A 401 ( 4.8A)
1.21A 4acaB-4oqqA:
undetectable
4acaC-4oqqA:
undetectable
4acaB-4oqqA:
21.34
4acaC-4oqqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 9 ILE A 144
GLY A 143
VAL A 149
THR A 151
ARG A 213
None
None
None
None
BCN  A 401 ( 4.8A)
1.23A 4acaB-4oqqA:
undetectable
4acaC-4oqqA:
undetectable
4acaB-4oqqA:
21.34
4acaC-4oqqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 9 ILE A 144
GLY A 143
VAL A 149
THR A 151
ARG A 282
None
None
None
None
BCN  A 401 ( 4.8A)
1.06A 4acaB-4oqqA:
undetectable
4acaC-4oqqA:
undetectable
4acaB-4oqqA:
21.34
4acaC-4oqqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 GLY A  98
ALA A 296
VAL A 277
MET A 120
PHE A 160
None
1.30A 4j4vA-4oqqA:
undetectable
4j4vA-4oqqA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_B_SVRB301_1
(NUCLEOCAPSID PROTEIN)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 10 GLY A  98
ALA A 296
VAL A 277
MET A 120
PHE A 160
None
1.31A 4j4vB-4oqqA:
undetectable
4j4vB-4oqqA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 GLY A  98
ALA A 296
VAL A 277
MET A 120
PHE A 160
None
1.30A 4j4vD-4oqqA:
undetectable
4j4vE-4oqqA:
undetectable
4j4vD-4oqqA:
24.22
4j4vE-4oqqA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_E_SVRE301_1
(NUCLEOCAPSID PROTEIN)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 10 GLY A  98
ALA A 296
VAL A 277
MET A 120
PHE A 160
None
1.31A 4j4vA-4oqqA:
undetectable
4j4vE-4oqqA:
undetectable
4j4vA-4oqqA:
24.22
4j4vE-4oqqA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.20A 4qvmV-4oqqA:
undetectable
4qvmb-4oqqA:
undetectable
4qvmV-4oqqA:
22.30
4qvmb-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.20A 4qvmH-4oqqA:
undetectable
4qvmN-4oqqA:
undetectable
4qvmH-4oqqA:
22.30
4qvmN-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.20A 4qvqV-4oqqA:
undetectable
4qvqb-4oqqA:
undetectable
4qvqV-4oqqA:
22.30
4qvqb-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.22A 4qw0V-4oqqA:
undetectable
4qw0b-4oqqA:
undetectable
4qw0V-4oqqA:
22.30
4qw0b-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 4qw0H-4oqqA:
undetectable
4qw0N-4oqqA:
undetectable
4qw0H-4oqqA:
22.30
4qw0N-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 4qw3V-4oqqA:
undetectable
4qw3b-4oqqA:
undetectable
4qw3V-4oqqA:
22.30
4qw3b-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.20A 4qw3H-4oqqA:
undetectable
4qw3N-4oqqA:
undetectable
4qw3H-4oqqA:
22.30
4qw3N-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 5d0xV-4oqqA:
undetectable
5d0xb-4oqqA:
undetectable
5d0xV-4oqqA:
22.30
5d0xb-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 5d0xH-4oqqA:
undetectable
5d0xN-4oqqA:
undetectable
5d0xH-4oqqA:
22.30
5d0xN-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 5l5zV-4oqqA:
undetectable
5l5zb-4oqqA:
undetectable
5l5zV-4oqqA:
22.30
5l5zb-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 5l5zH-4oqqA:
undetectable
5l5zN-4oqqA:
undetectable
5l5zH-4oqqA:
22.30
5l5zN-4oqqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 11 PHE A 207
THR A 105
GLU A 272
ILE A 204
ALA A 205
None
1.00A 5lg3A-4oqqA:
undetectable
5lg3A-4oqqA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 PHE A 207
THR A 105
GLU A 272
ILE A 204
ALA A 205
None
1.03A 5lg3E-4oqqA:
undetectable
5lg3E-4oqqA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 6hwdV-4oqqA:
undetectable
6hwdb-4oqqA:
undetectable
6hwdV-4oqqA:
15.83
6hwdb-4oqqA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)
4oqq DEOXYRIBONUCLEOSIDE
REGULATOR

(Bacillus
subtilis)
5 / 12 THR A 208
THR A 118
THR A 151
ARG A 282
GLY A 210
BCN  A 401 (-3.5A)
BCN  A 401 (-3.2A)
None
BCN  A 401 ( 4.8A)
BCN  A 401 (-3.6A)
1.21A 6hwdH-4oqqA:
undetectable
6hwdN-4oqqA:
undetectable
6hwdH-4oqqA:
15.83
6hwdN-4oqqA:
13.95