SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		5 / 11 ALA A 165
GLY A 117
TYR A 169
ALA A 102
TYR A  69
 None
 1.31A 3qxyB-4oqzA:
undetectable
3qxyQ-4oqzA:
undetectable		 3qxyB-4oqzA:
19.96
3qxyQ-4oqzA:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		5 / 9 ALA A 166
GLY A 116
LEU A 119
LEU A  91
ASN A  90
 None
 1.19A 3wdmC-4oqzA:
4.2		 3wdmC-4oqzA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		6 / 11 ILE A  63
TYR A  26
GLN A   3
LEU A  61
VAL A  87
LEU A 148
 None
 1.40A 4g1bB-4oqzA:
2.2		 4g1bB-4oqzA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		6 / 12 ILE A  63
TYR A  26
GLN A   3
LEU A  61
VAL A  87
LEU A 148
 None
 1.37A 4g1bD-4oqzA:
4.6		 4g1bD-4oqzA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		5 / 12 TYR A  69
HIS A 113
ALA A 166
ILE A 151
MET A  17
 None
 1.36A 5iwuA-4oqzA:
undetectable		 5iwuA-4oqzA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		3 / 3 SER A 135
TYR A 134
TYR A 157
 None
 0.77A 5lakA-4oqzA:
undetectable
5lakI-4oqzA:
undetectable		 5lakA-4oqzA:
24.50
5lakI-4oqzA:
2.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		3 / 3 SER A 135
TYR A 134
TYR A 157
 None
 0.79A 5lakC-4oqzA:
undetectable
5lakJ-4oqzA:
undetectable		 5lakC-4oqzA:
24.50
5lakJ-4oqzA:
2.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		5 / 12 ALA A  16
PRO A 121
SER A 127
ASP A  23
ALA A  19
 None
 1.33A 5zvgA-4oqzA:
4.7		 5zvgA-4oqzA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		4 / 5 PRO A  52
VAL A  75
GLY A  85
VAL A  62
 None
 1.10A 6ak3B-4oqzA:
undetectable		 6ak3B-4oqzA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4oqz PUTATIVE
OXIDOREDUCTASE YFJR
(Streptomyces
aurantiacus) 		4 / 5 PRO A  52
VAL A  75
GLY A 111
VAL A  62
 None
 1.11A 6ak3B-4oqzA:
undetectable		 6ak3B-4oqzA:
14.39