SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4orl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WMQ_A_HISA2001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	4orl	UNCHARACTERIZED PROTEIN (Bacteroides ovatus)	4 / 6	ARG A 106 ILE A 95 GLY A 96 HIS A 84	None	1.00A	1wmqA-4orlA: undetectable	1wmqA-4orlA: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WPU_B_HISB1001_0 (HUT OPERON POSITIVE REGULATORY PROTEIN)	4orl	UNCHARACTERIZED PROTEIN (Bacteroides ovatus)	4 / 6	ARG A 106 ILE A 95 GLY A 96 HIS A 84	None	1.00A	1wpuB-4orlA: undetectable	1wpuB-4orlA: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZQ9_A_SAMA4000_1 (PROBABLE DIMETHYLADENOSINE TRANSFERASE)	4orl	UNCHARACTERIZED PROTEIN (Bacteroides ovatus)	3 / 3	GLY A 103 GLU A 130 ASN A 102	None	0.72A	1zq9A-4orlA: undetectable	1zq9A-4orlA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HJH_A_NCAA900_0 (NAD-DEPENDENT HISTONE DEACETYLASE SIR2)	4orl	UNCHARACTERIZED PROTEIN (Bacteroides ovatus)	4 / 5	ILE A 24 PHE A 80 PHE A 32 ILE A 95	None	1.05A	2hjhA-4orlA: undetectable	2hjhA-4orlA: 16.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WMQ_A_HISA2001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","4orl","UNCHARACTERIZED PROTEIN","Bacteroides ovatus",4,"ARG A 106;ILE A  95;GLY A  96;HIS A  84","None","1.00A","1wmqA-4orlA:undetectable","1wmqA-4orlA:23.72"],["1WPU_B_HISB1001_0","HUT OPERON POSITIVE REGULATORY PROTEIN","4orl","UNCHARACTERIZED PROTEIN","Bacteroides ovatus",4,"ARG A 106;ILE A  95;GLY A  96;HIS A  84","None","1.00A","1wpuB-4orlA:undetectable","1wpuB-4orlA:23.72"],["1ZQ9_A_SAMA4000_1","PROBABLE DIMETHYLADENOSINE TRANSFERASE","4orl","UNCHARACTERIZED PROTEIN","Bacteroides ovatus",3,"GLY A 103;GLU A 130;ASN A 102","None","0.72A","1zq9A-4orlA:undetectable","1zq9A-4orlA:20.36"],["2HJH_A_NCAA900_0","NAD-DEPENDENT HISTONE DEACETYLASE SIR2","4orl","UNCHARACTERIZED PROTEIN","Bacteroides ovatus",4,"ILE A  24;PHE A  80;PHE A  32;ILE A  95","None","1.05A","2hjhA-4orlA:undetectable","2hjhA-4orlA:16.22"]]