SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4orz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 7 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.13A 1v55C-4orzB:
undetectable
1v55N-4orzB:
undetectable
1v55P-4orzB:
undetectable		 1v55C-4orzB:
18.94
1v55N-4orzB:
13.41
1v55P-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		5 / 9 PRO B 154
PRO B 151
VAL B 150
GLU C  48
ALA C  62
 None
 1.49A 2v41A-4orzB:
undetectable
2v41B-4orzB:
undetectable		 2v41A-4orzB:
20.72
2v41B-4orzB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 VAL B 150
TRP B 106
TRP B 187
 None
 1.48A 2xdcC-4orzB:
undetectable
2xdcD-4orzB:
undetectable		 2xdcC-4orzB:
18.37
2xdcD-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 TRP B 187
VAL B 150
TRP B 106
 None
 1.01A 2xdcC-4orzB:
undetectable
2xdcD-4orzB:
undetectable		 2xdcC-4orzB:
18.37
2xdcD-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 TRP B 187
VAL B 150
TRP B 106
 None
 1.02A 2xdcE-4orzB:
undetectable
2xdcF-4orzB:
undetectable		 2xdcE-4orzB:
18.37
2xdcF-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 TRP B 187
VAL B 150
TRP B 106
 None
 1.03A 2y5mE-4orzB:
undetectable
2y5mF-4orzB:
undetectable		 2y5mE-4orzB:
18.37
2y5mF-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.09A 2y69C-4orzB:
undetectable
2y69N-4orzB:
undetectable
2y69P-4orzB:
undetectable		 2y69C-4orzB:
18.94
2y69N-4orzB:
13.41
2y69P-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 TRP B 187
VAL B 150
TRP B 106
 None
 1.01A 2y6nC-4orzB:
undetectable
2y6nD-4orzB:
undetectable		 2y6nC-4orzB:
18.37
2y6nD-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 TRP B 187
VAL B 150
TRP B 106
 None
 1.02A 2y6nE-4orzB:
undetectable
2y6nF-4orzB:
undetectable		 2y6nE-4orzB:
18.37
2y6nF-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.13A 3ablC-4orzB:
undetectable
3ablN-4orzB:
undetectable
3ablP-4orzB:
undetectable		 3ablC-4orzB:
18.94
3ablN-4orzB:
13.41
3ablP-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.13A 3abmA-4orzC:
undetectable
3abmC-4orzC:
undetectable
3abmP-4orzC:
undetectable		 3abmA-4orzC:
11.54
3abmC-4orzC:
18.39
3abmP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.16A 3asnC-4orzB:
undetectable
3asnN-4orzB:
undetectable
3asnP-4orzB:
undetectable		 3asnC-4orzB:
18.94
3asnN-4orzB:
13.41
3asnP-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.17A 3asoA-4orzC:
undetectable
3asoC-4orzC:
undetectable
3asoP-4orzC:
undetectable		 3asoA-4orzC:
11.54
3asoC-4orzC:
18.39
3asoP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.17A 3asoC-4orzB:
undetectable
3asoN-4orzB:
undetectable
3asoP-4orzB:
undetectable		 3asoC-4orzB:
18.94
3asoN-4orzB:
13.41
3asoP-4orzB:
18.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 4orz SINGLE DOMAIN
ANTIBODY SDAB19
(Lama
glama) 		5 / 12 ALA C  26
MET C  36
ARG C  73
ASN C  78
VAL C  80
 None
 0.96A 3qxtA-4orzC:
20.7		 3qxtA-4orzC:
65.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		4 / 4 GLY B 136
GLY B 134
THR B 132
LEU B 202
 None
 0.68A 3si7C-4orzB:
undetectable
3si7D-4orzB:
undetectable		 3si7C-4orzB:
18.95
3si7D-4orzB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		4 / 5 LEU B 202
GLY B 136
GLY B 134
THR B 132
 None
 0.67A 3si7C-4orzB:
undetectable
3si7D-4orzB:
undetectable		 3si7C-4orzB:
18.95
3si7D-4orzB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.13A 3wg7A-4orzC:
undetectable
3wg7C-4orzC:
undetectable
3wg7P-4orzC:
undetectable		 3wg7A-4orzC:
11.54
3wg7C-4orzC:
18.39
3wg7P-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.13A 3wg7C-4orzB:
undetectable
3wg7N-4orzB:
undetectable
3wg7P-4orzB:
undetectable		 3wg7C-4orzB:
18.94
3wg7N-4orzB:
13.41
3wg7P-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.12A 3x2qA-4orzC:
undetectable
3x2qC-4orzC:
undetectable
3x2qP-4orzC:
undetectable		 3x2qA-4orzC:
11.54
3x2qC-4orzC:
18.39
3x2qP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.14A 3x2qC-4orzB:
undetectable
3x2qN-4orzB:
undetectable
3x2qP-4orzB:
undetectable		 3x2qC-4orzB:
18.94
3x2qN-4orzB:
13.41
3x2qP-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 VAL B 150
TRP B 106
TRP B 187
 None
 1.43A 3zq8A-4orzB:
undetectable
3zq8B-4orzB:
undetectable		 3zq8A-4orzB:
18.37
3zq8B-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 4orz PROTEIN NEF
(Human
immunodeficiency
virus
1) 		3 / 3 TRP B 187
VAL B 150
TRP B 106
 None
 1.17A 3zq8A-4orzB:
undetectable
3zq8B-4orzB:
undetectable		 3zq8A-4orzB:
18.37
3zq8B-4orzB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.12A 5b1aA-4orzC:
undetectable
5b1aC-4orzC:
undetectable
5b1aP-4orzC:
undetectable		 5b1aA-4orzC:
11.54
5b1aC-4orzC:
18.39
5b1aP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.14A 5b3sA-4orzC:
undetectable
5b3sC-4orzC:
undetectable
5b3sP-4orzC:
undetectable		 5b3sA-4orzC:
11.54
5b3sC-4orzC:
18.39
5b3sP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.16A 5iy5C-4orzB:
undetectable
5iy5N-4orzB:
undetectable
5iy5P-4orzB:
undetectable		 5iy5C-4orzB:
19.31
5iy5N-4orzB:
13.41
5iy5P-4orzB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.09A 5w97A-4orzC:
undetectable
5w97C-4orzC:
undetectable
5w97c-4orzC:
undetectable		 5w97A-4orzC:
11.54
5w97C-4orzC:
18.39
5w97c-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 7 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.09A 5w97C-4orzB:
undetectable
5w97a-4orzB:
undetectable
5w97c-4orzB:
undetectable		 5w97C-4orzB:
18.94
5w97a-4orzB:
13.41
5w97c-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.12A 5wauA-4orzC:
undetectable
5wauC-4orzC:
undetectable
5wauc-4orzC:
undetectable		 5wauA-4orzC:
11.54
5wauC-4orzC:
18.39
5wauc-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 7 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.13A 5wauC-4orzB:
undetectable
5waua-4orzB:
undetectable
5wauc-4orzB:
undetectable		 5wauC-4orzB:
18.94
5waua-4orzB:
13.41
5wauc-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.15A 5x19A-4orzC:
undetectable
5x19C-4orzC:
undetectable
5x19P-4orzC:
undetectable		 5x19A-4orzC:
11.54
5x19C-4orzC:
18.39
5x19P-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 7 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.15A 5x1fA-4orzC:
undetectable
5x1fC-4orzC:
undetectable
5x1fP-4orzC:
undetectable		 5x1fA-4orzC:
11.54
5x1fC-4orzC:
18.39
5x1fP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.13A 5xdqA-4orzC:
undetectable
5xdqC-4orzC:
undetectable
5xdqP-4orzC:
undetectable		 5xdqA-4orzC:
11.54
5xdqC-4orzC:
18.39
5xdqP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.14A 5xdqC-4orzB:
undetectable
5xdqN-4orzB:
undetectable
5xdqP-4orzB:
undetectable		 5xdqC-4orzB:
18.94
5xdqN-4orzB:
13.41
5xdqP-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.15A 5xdxC-4orzB:
undetectable
5xdxN-4orzB:
undetectable
5xdxP-4orzB:
undetectable		 5xdxC-4orzB:
19.01
5xdxN-4orzB:
13.41
5xdxP-4orzB:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.09A 5z84A-4orzC:
undetectable
5z84C-4orzC:
undetectable
5z84P-4orzC:
undetectable		 5z84A-4orzC:
11.54
5z84C-4orzC:
18.39
5z84P-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 7 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.15A 5z84C-4orzB:
undetectable
5z84N-4orzB:
undetectable
5z84P-4orzB:
undetectable		 5z84C-4orzB:
18.94
5z84N-4orzB:
13.41
5z84P-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.07A 5z85A-4orzC:
undetectable
5z85C-4orzC:
undetectable
5z85P-4orzC:
undetectable		 5z85A-4orzC:
11.54
5z85C-4orzC:
18.39
5z85P-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 7 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.14A 5z85C-4orzB:
undetectable
5z85N-4orzB:
undetectable
5z85P-4orzB:
undetectable		 5z85C-4orzB:
18.94
5z85N-4orzB:
13.41
5z85P-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.08A 5z86A-4orzC:
undetectable
5z86C-4orzC:
undetectable
5z86P-4orzC:
undetectable		 5z86A-4orzC:
11.54
5z86C-4orzC:
18.39
5z86P-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.15A 5z86C-4orzB:
undetectable
5z86N-4orzB:
undetectable
5z86P-4orzB:
undetectable		 5z86C-4orzB:
18.94
5z86N-4orzB:
13.41
5z86P-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.11A 5zcoA-4orzC:
undetectable
5zcoC-4orzC:
undetectable
5zcoP-4orzC:
undetectable		 5zcoA-4orzC:
11.54
5zcoC-4orzC:
18.39
5zcoP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.13A 5zcoC-4orzB:
undetectable
5zcoN-4orzB:
undetectable
5zcoP-4orzB:
undetectable		 5zcoC-4orzB:
18.94
5zcoN-4orzB:
13.41
5zcoP-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.10A 5zcpA-4orzC:
undetectable
5zcpC-4orzC:
undetectable
5zcpP-4orzC:
undetectable		 5zcpA-4orzC:
11.54
5zcpC-4orzC:
18.39
5zcpP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.14A 5zcpC-4orzB:
undetectable
5zcpN-4orzB:
undetectable
5zcpP-4orzB:
undetectable		 5zcpC-4orzB:
18.94
5zcpN-4orzB:
13.41
5zcpP-4orzB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 ASP C  60
THR C  59
TYR C  58
LEU B 193
 None
 1.10A 5zcqA-4orzC:
undetectable
5zcqC-4orzC:
undetectable
5zcqP-4orzC:
undetectable		 5zcqA-4orzC:
11.54
5zcqC-4orzC:
18.39
5zcqP-4orzC:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4orz PROTEIN NEF
SINGLE DOMAIN
ANTIBODY SDAB19
(Human
immunodeficiency
virus
1;
Lama
glama) 		4 / 8 LEU B 193
ASP C  60
THR C  59
TYR C  58
 None
 1.16A 6nknC-4orzB:
undetectable
6nknN-4orzB:
undetectable
6nknP-4orzB:
undetectable		 6nknC-4orzB:
18.94
6nknN-4orzB:
13.41
6nknP-4orzB:
18.94