SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ose'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 11 ILE A 237
SER A 242
GLY A 268
GLY A 239
ASP A 136
 None
 1.34A 1ho5A-4oseA:
undetectable		 1ho5A-4oseA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 9 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.90A 1hshB-4oseA:
undetectable		 1hshB-4oseA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.95A 1kifA-4oseA:
undetectable		 1kifA-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.94A 1kifB-4oseA:
undetectable		 1kifB-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.95A 1kifC-4oseA:
undetectable		 1kifC-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.94A 1kifD-4oseA:
undetectable		 1kifD-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.95A 1kifE-4oseA:
undetectable		 1kifE-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.94A 1kifF-4oseA:
undetectable		 1kifF-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.94A 1kifG-4oseA:
undetectable		 1kifG-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.94A 1kifH-4oseA:
undetectable		 1kifH-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.94A 1ve9A-4oseA:
undetectable		 1ve9A-4oseA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 6 GLY A  44
SER A 112
ILE A 149
HIS A 269
 None
 0.93A 1yajF-4oseA:
11.2		 1yajF-4oseA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 4 GLY A  44
SER A 112
ILE A 149
HIS A 269
 None
 0.95A 1yajJ-4oseA:
6.3		 1yajJ-4oseA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.74A 2b60A-4oseA:
undetectable		 2b60A-4oseA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 6 ALA A 153
TYR A 173
ILE A 149
ILE A 172
 None
 1.25A 2dcfA-4oseA:
undetectable		 2dcfA-4oseA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		4 / 5 TYR A  85
ILE A  20
ARG A  73
GLY A  72
 None
 0.91A 2du8G-4oseA:
undetectable		 2du8G-4oseA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.87A 2hs1A-4oseA:
undetectable		 2hs1A-4oseA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.85A 2rkgB-4oseA:
undetectable		 2rkgB-4oseA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 10 ALA A  49
ILE A  66
ILE A   6
PHE A  97
TYR A  70
 None
 1.16A 2w9sC-4oseA:
undetectable		 2w9sC-4oseA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 11 LEU A  59
TYR A 281
LEU A 286
TYR A  63
GLU A  58
 None
 1.40A 3bgrA-4oseA:
undetectable
3bgrB-4oseA:
undetectable		 3bgrA-4oseA:
20.29
3bgrB-4oseA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 9 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.95A 3nu4A-4oseA:
undetectable		 3nu4A-4oseA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 9 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.84A 3nu4B-4oseA:
undetectable		 3nu4B-4oseA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 LEU A 132
PHE A 129
ILE A  55
ALA A  56
GLU A  29
 None
 1.01A 3nxuA-4oseA:
undetectable		 3nxuA-4oseA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 9 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.91A 3s43A-4oseA:
undetectable		 3s43A-4oseA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 9 ALA A 122
ILE A 234
GLY A 115
ILE A 116
ILE A 230
 None
 0.90A 3s45A-4oseA:
undetectable		 3s45A-4oseA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 PRO A 106
TRP A 108
LEU A  40
ILE A 103
TYR A  11
 None
 1.37A 4a79A-4oseA:
undetectable		 4a79A-4oseA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 PRO A 106
TRP A 108
LEU A  40
ILE A 103
TYR A  11
 None
 1.39A 4a79B-4oseA:
undetectable		 4a79B-4oseA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 PRO A 106
TRP A 108
LEU A  40
ILE A 128
ILE A 103
 None
 1.46A 4a79B-4oseA:
undetectable		 4a79B-4oseA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		3 / 3 VAL A 221
ALA A 143
PHE A 140
 None
 0.91A 4z4iA-4oseA:
3.2		 4z4iA-4oseA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		3 / 3 VAL A 221
ALA A 143
PHE A 140
 None
 0.90A 5js1A-4oseA:
undetectable		 5js1A-4oseA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 GLY A 239
GLY A 177
ASP A 136
LEU A 245
MET A 240
 None
 1.14A 5yniA-4oseA:
undetectable		 5yniA-4oseA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 GLY A 239
GLY A 177
ASP A 136
LEU A 245
MET A 240
 None
 1.12A 5ynmA-4oseA:
2.1		 5ynmA-4oseA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 4ose PUTATIVE HYDROLASE
(Rickettsia
typhi) 		5 / 12 ALA A 122
GLY A 110
GLY A 115
ILE A 116
ILE A 230
 None
 0.88A 6dj1A-4oseA:
undetectable		 6dj1A-4oseA:
13.76