SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ot1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4ot1 ENVELOPE
GLYCOPROTEIN B
(Human
betaherpesvirus
5) 		3 / 3 TYR A 415
GLU A 359
ASP A 362
 None
 0.78A 3bxoB-4ot1A:
undetectable		 3bxoB-4ot1A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 10 VAL H 181
VAL H 200
SER H 198
ASN H 215
ASN H 173
 None
 1.48A 4ldoA-4ot1H:
undetectable		 4ldoA-4ot1H:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.23A 4v2yA-4ot1H:
undetectable		 4v2yA-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.20A 4v2yB-4ot1H:
undetectable		 4v2yB-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.23A 4v2zA-4ot1H:
undetectable		 4v2zA-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.21A 4v2zB-4ot1H:
undetectable		 4v2zB-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.24A 4v30A-4ot1H:
undetectable		 4v30A-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.21A 4v30B-4ot1H:
undetectable		 4v30B-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.20A 5amiA-4ot1H:
undetectable		 5amiA-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.20A 5amiB-4ot1H:
undetectable		 5amiB-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.17A 5amjA-4ot1H:
undetectable		 5amjA-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.18A 5amjB-4ot1H:
undetectable		 5amjB-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.27A 5oh1B-4ot1H:
undetectable		 5oh1B-4ot1H:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.20A 5oh3A-4ot1H:
undetectable		 5oh3A-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.24A 5oh3B-4ot1H:
undetectable		 5oh3B-4ot1H:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ot1 SM5-1 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 VAL H 181
VAL H 200
SER H 198
ASN H 215
ASN H 173
 None
 1.45A 6h7mB-4ot1H:
undetectable		 6h7mB-4ot1H:
17.04