SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4otu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOI_C_FRDC305_2 (POL POLYPROTEIN PEPTIDE INHIBITOR)	4otu	GAMMA-GLUTAMYLTRANSP EPTIDASE (Bacillus licheniformis)	4 / 5	LEU B 435 PRO B 429 VAL B 428 ILE B 426	None	0.82A	2aoiB-4otuB: undetectable	2aoiB-4otuB: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UVN_A_ECNA1409_1 (CYTOCHROME P450 130)	4otu	GAMMA-GLUTAMYLTRANSP EPTIDASE (Bacillus licheniformis)	5 / 12	LEU B 459 THR B 483 GLY B 482 GLY B 481 THR B 399	None None GLU B 602 (-3.1A) GLU B 602 ( 4.2A) GLU B 602 (-2.7A)	1.16A	2uvnA-4otuB: undetectable	2uvnA-4otuB: 17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H5F_A_SAMA301_1 (PROTEIN ARGININE N-METHYLTRANSFERASE SFM1)	4otu	GAMMA-GLUTAMYLTRANSP EPTIDASE (Bacillus licheniformis)	4 / 5	GLY B 481 PRO B 464 THR B 399 THR B 484	GLU B 602 ( 4.2A) None GLU B 602 (-2.7A) None	1.07A	5h5fA-4otuB: undetectable	5h5fA-4otuB: 24.69