SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oue'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A 147
LEU A 146
TYR A 145
GLY A 102
GLU A 174
 None
None
GOL  A 501 (-4.5A)
None
None
 1.09A 1iolA-4oueA:
2.1		 1iolA-4oueA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A 114
TYR A 110
SER A 156
ASP A 112
 None
 1.37A 1vidA-4oueA:
undetectable		 1vidA-4oueA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 229
THR A 246
LEU A  30
ALA A 244
 None
 1.24A 2e1qD-4oueA:
undetectable		 2e1qD-4oueA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 236
GLY A 232
ILE A 303
ASP A 277
VAL A 278
 None
None
None
IPT  A 502 (-2.9A)
None
 0.98A 2oxtC-4oueA:
undetectable		 2oxtC-4oueA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 154
GLU A 153
HIS A 152
 None
 0.83A 3ba0A-4oueA:
undetectable		 3ba0A-4oueA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE A 341
ASN A  41
VAL A 308
GLY A 309
 None
 0.55A 3em0B-4oueA:
undetectable		 3em0B-4oueA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  97
LEU A 172
LEU A 175
MET A 176
ARG A 129
 None
 1.42A 3lbdA-4oueA:
undetectable		 3lbdA-4oueA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 259
GLU A 263
TRP A 243
 None
 1.25A 3v4tH-4oueA:
0.1		 3v4tH-4oueA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 175
GLY A 147
TYR A 168
ASP A 150
GLY A 102
 None
 1.25A 4bwlC-4oueA:
7.4		 4bwlC-4oueA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 459
ILE A 441
ILE A 390
ALA A 388
PHE A 379
 None
 1.23A 4rp8C-4oueA:
undetectable		 4rp8C-4oueA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 206
VAL A 207
PHE A 217
HIS A 170
 None
 1.38A 4rzvA-4oueA:
undetectable		 4rzvA-4oueA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 299
THR A 329
HIS A 333
 None
 0.77A 4ydqB-4oueA:
undetectable		 4ydqB-4oueA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A 114
TYR A 110
SER A 156
ASP A 112
 None
 1.37A 5fhrA-4oueA:
undetectable		 5fhrA-4oueA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A  55
ILE A  52
ASN A  72
PRO A 107
 None
 1.10A 5x23A-4oueA:
undetectable		 5x23A-4oueA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 405
PHE A 473
ARG A 460
THR A 436
 None
 1.27A 5z84N-4oueA:
undetectable
5z84W-4oueA:
undetectable		 5z84N-4oueA:
18.95
5z84W-4oueA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 4oue PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 TRP A  39
GLU A 275
THR A 306
TRP A 301
 None
 1.36A 6j21A-4oueA:
0.0		 6j21A-4oueA:
22.59