SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2003_1 (SERUM ALBUMIN)	4oun	MINI-RIBONUCLEASE 3 (Bacillus subtilis)	5 / 10	LEU A 129 PHE A 46 LEU A 85 ILE A 81 ALA A 146	None	0.93A	2bxeB-4ounA: 2.6	2bxeB-4ounA: 14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	4oun	MINI-RIBONUCLEASE 3 (Bacillus subtilis)	5 / 12	LEU A 129 PHE A 46 LEU A 85 ILE A 81 ALA A 146	None	0.96A	2bxpA-4ounA: undetectable	2bxpA-4ounA: 14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	4oun	MINI-RIBONUCLEASE 3 (Bacillus subtilis)	5 / 12	LEU A 129 PHE A 46 LEU A 85 ILE A 81 ALA A 146	None	0.99A	2bxqA-4ounA: undetectable	2bxqA-4ounA: 14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NV4_A_ACTA148_0 (UPF0066 PROTEIN AF_0241)	4oun	MINI-RIBONUCLEASE 3 (Bacillus subtilis)	3 / 3	VAL A 98 GLU A 94 GLU A 95	None	0.80A	2nv4A-4ounA: undetectable	2nv4A-4ounA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	4oun	MINI-RIBONUCLEASE 3 (Bacillus subtilis)	4 / 6	THR A 92 PHE A 91 LEU A 132 LEU A 128	None	1.08A	3bgdA-4ounA: undetectable	3bgdA-4ounA: 29.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BXE_B_1FLB2003_1","SERUM ALBUMIN","4oun","MINI-RIBONUCLEASE 3","Bacillus subtilis",5,"LEU A 129;PHE A  46;LEU A  85;ILE A  81;ALA A 146","None","0.93A","2bxeB-4ounA:2.6","2bxeB-4ounA:14.44"],["2BXP_A_P1ZA3001_1","SERUM ALBUMIN","4oun","MINI-RIBONUCLEASE 3","Bacillus subtilis",5,"LEU A 129;PHE A  46;LEU A  85;ILE A  81;ALA A 146","None","0.96A","2bxpA-4ounA:undetectable","2bxpA-4ounA:14.44"],["2BXQ_A_P1ZA2002_1","SERUM ALBUMIN","4oun","MINI-RIBONUCLEASE 3","Bacillus subtilis",5,"LEU A 129;PHE A  46;LEU A  85;ILE A  81;ALA A 146","None","0.99A","2bxqA-4ounA:undetectable","2bxqA-4ounA:14.44"],["2NV4_A_ACTA148_0","UPF0066 PROTEIN AF_0241","4oun","MINI-RIBONUCLEASE 3","Bacillus subtilis",3,"VAL A  98;GLU A  94;GLU A  95","None","0.80A","2nv4A-4ounA:undetectable","2nv4A-4ounA:19.05"],["3BGD_A_PM6A302_1","THIOPURINE S-METHYLTRANSFERASE","4oun","MINI-RIBONUCLEASE 3","Bacillus subtilis",4,"THR A  92;PHE A  91;LEU A 132;LEU A 128","None","1.08A","3bgdA-4ounA:undetectable","3bgdA-4ounA:29.59"]]