SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ouo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		5 / 12 PHE A  61
GLY A  63
SER A  64
THR A  71
ASN A  52
 None
 1.23A 1g60A-4ouoA:
undetectable		 1g60A-4ouoA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.21A 1zzrA-4ouoA:
undetectable
1zzrB-4ouoA:
undetectable		 1zzrA-4ouoA:
20.56
1zzrB-4ouoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.22A 1zzrA-4ouoA:
undetectable
1zzrB-4ouoA:
undetectable		 1zzrA-4ouoA:
20.56
1zzrB-4ouoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.20A 1zzuA-4ouoA:
undetectable
1zzuB-4ouoA:
undetectable		 1zzuA-4ouoA:
20.56
1zzuB-4ouoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.19A 1zzuA-4ouoA:
undetectable
1zzuB-4ouoA:
undetectable		 1zzuA-4ouoA:
20.56
1zzuB-4ouoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		5 / 12 ASN A 197
LEU A 199
ALA A 131
GLN A 126
LEU A 134
 None
 1.41A 2oaxF-4ouoA:
undetectable		 2oaxF-4ouoA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.25A 3dqrA-4ouoA:
undetectable
3dqrB-4ouoA:
undetectable		 3dqrA-4ouoA:
20.28
3dqrB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.27A 3dqrA-4ouoA:
undetectable
3dqrB-4ouoA:
undetectable		 3dqrA-4ouoA:
20.28
3dqrB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.14A 3jx2A-4ouoA:
undetectable
3jx2B-4ouoA:
undetectable		 3jx2A-4ouoA:
20.28
3jx2B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.19A 3jx2A-4ouoA:
undetectable
3jx2B-4ouoA:
undetectable		 3jx2A-4ouoA:
20.28
3jx2B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.19A 3jx3A-4ouoA:
undetectable
3jx3B-4ouoA:
undetectable		 3jx3A-4ouoA:
20.28
3jx3B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.14A 3jx3A-4ouoA:
undetectable
3jx3B-4ouoA:
undetectable		 3jx3A-4ouoA:
20.28
3jx3B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.21A 3jx4A-4ouoA:
undetectable
3jx4B-4ouoA:
undetectable		 3jx4A-4ouoA:
20.28
3jx4B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.17A 3jx5A-4ouoA:
undetectable
3jx5B-4ouoA:
undetectable		 3jx5A-4ouoA:
20.28
3jx5B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.18A 3jx5A-4ouoA:
undetectable
3jx5B-4ouoA:
undetectable		 3jx5A-4ouoA:
20.28
3jx5B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.11A 3jx6A-4ouoA:
undetectable
3jx6B-4ouoA:
undetectable		 3jx6A-4ouoA:
20.28
3jx6B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.14A 3jx6A-4ouoA:
undetectable
3jx6B-4ouoA:
undetectable		 3jx6A-4ouoA:
20.28
3jx6B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.13A 3nljA-4ouoA:
undetectable
3nljB-4ouoA:
undetectable		 3nljA-4ouoA:
20.28
3nljB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.14A 3nljA-4ouoA:
undetectable
3nljB-4ouoA:
undetectable		 3nljA-4ouoA:
20.28
3nljB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.15A 3nlpA-4ouoA:
undetectable
3nlpB-4ouoA:
undetectable		 3nlpA-4ouoA:
20.28
3nlpB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.17A 3nlpA-4ouoA:
undetectable
3nlpB-4ouoA:
undetectable		 3nlpA-4ouoA:
20.28
3nlpB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 8 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.15A 3nlqA-4ouoA:
undetectable
3nlqB-4ouoA:
undetectable		 3nlqA-4ouoA:
20.28
3nlqB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.21A 3nlqA-4ouoA:
undetectable
3nlqB-4ouoA:
undetectable		 3nlqA-4ouoA:
20.28
3nlqB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.14A 3nlrA-4ouoA:
undetectable
3nlrB-4ouoA:
undetectable		 3nlrA-4ouoA:
20.28
3nlrB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		6 / 12 VAL A 116
ALA A 138
MET A 148
ARG A 185
ASN A 187
VAL A 192
 None
 0.87A 3qxvA-4ouoA:
20.6		 3qxvA-4ouoA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		5 / 12 VAL A 116
ALA A 138
MET A 148
ARG A 185
VAL A 192
 None
 0.92A 3qxvB-4ouoA:
13.3		 3qxvB-4ouoA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		6 / 11 VAL A 116
ALA A 138
MET A 148
ARG A 185
ASN A 187
VAL A 192
 None
 0.90A 3qxvC-4ouoA:
20.9		 3qxvC-4ouoA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.21A 4cx3A-4ouoA:
undetectable
4cx3B-4ouoA:
undetectable		 4cx3A-4ouoA:
20.28
4cx3B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.18A 4cx3A-4ouoA:
undetectable
4cx3B-4ouoA:
undetectable		 4cx3A-4ouoA:
20.28
4cx3B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.22A 4cx4A-4ouoA:
undetectable
4cx4B-4ouoA:
undetectable		 4cx4A-4ouoA:
20.28
4cx4B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.17A 4cx4A-4ouoA:
undetectable
4cx4B-4ouoA:
undetectable		 4cx4A-4ouoA:
20.28
4cx4B-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 8 LEU A 132
ARG A 152
VAL A 229
VAL A 231
 None
 0.99A 4em2A-4ouoA:
undetectable		 4em2A-4ouoA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.16A 5addA-4ouoA:
undetectable
5addB-4ouoA:
undetectable		 5addA-4ouoA:
20.28
5addB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 VAL A 106
ARG A  60
VAL A  18
GLU A  82
 None
 1.19A 5g0pA-4ouoA:
undetectable
5g0pB-4ouoA:
undetectable		 5g0pA-4ouoA:
20.28
5g0pB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 7 GLU A  82
VAL A 106
ARG A  60
VAL A  18
 None
 1.20A 5g0pA-4ouoA:
undetectable
5g0pB-4ouoA:
undetectable		 5g0pA-4ouoA:
20.28
5g0pB-4ouoA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 4ouo ANTI BLA G 1 SCFV
(Gallus
gallus) 		4 / 8 THR A  73
SER A  62
THR A  71
SER A  64
 None
 1.03A 5l4eA-4ouoA:
undetectable
5l4eB-4ouoA:
undetectable
5l4eC-4ouoA:
undetectable
5l4eD-4ouoA:
undetectable
5l4eE-4ouoA:
undetectable		 5l4eA-4ouoA:
20.60
5l4eB-4ouoA:
20.60
5l4eC-4ouoA:
20.60
5l4eD-4ouoA:
20.60
5l4eE-4ouoA:
20.60