SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ouq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 4ouq UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A  50
ALA A  64
LEU A  68
ILE A 107
ILE A 120
 None
 0.90A 1fk6A-4ouqA:
undetectable		 1fk6A-4ouqA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4ouq UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A  68
ALA A  69
PHE A  71
ILE A 107
LEU A  98
 None
 0.87A 4pssA-4ouqA:
undetectable		 4pssA-4ouqA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4ouq UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A  68
ALA A  69
PHE A  71
ILE A 107
LEU A  98
 None
 0.85A 4psyA-4ouqA:
undetectable		 4psyA-4ouqA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 4ouq UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		5 / 11 PHE A  71
THR A  67
PHE A  32
ILE A 107
ILE A 123
 None
 0.92A 6gp2A-4ouqA:
undetectable		 6gp2A-4ouqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 4ouq UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		5 / 11 PHE A  71
THR A  67
PHE A  32
ILE A 107
ILE A 123
 None
 0.90A 6gp2B-4ouqA:
undetectable		 6gp2B-4ouqA:
21.82