SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ovj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.74A 1a7yB-4ovjA:
undetectable		 1a7yB-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.80A 1a7yB-4ovjA:
undetectable		 1a7yB-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.87A 1dscC-4ovjA:
undetectable		 1dscC-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.83A 1fjaC-4ovjA:
undetectable		 1fjaC-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.83A 1fjaD-4ovjA:
undetectable		 1fjaD-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.82A 1i3wE-4ovjA:
undetectable		 1i3wE-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.81A 1i3wG-4ovjA:
undetectable		 1i3wG-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.82A 1i3wG-4ovjA:
undetectable		 1i3wG-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.81A 1i3wH-4ovjA:
undetectable		 1i3wH-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 4 HIS A 177
ALA A 172
PHE A 171
GLY A 175
 None
 1.35A 1mj2B-4ovjA:
undetectable		 1mj2B-4ovjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 4 HIS A 177
ALA A 172
PHE A 171
GLY A 175
 None
 1.40A 1mj2D-4ovjA:
undetectable		 1mj2D-4ovjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 4 HIS A 177
ALA A 172
PHE A 171
GLY A 175
 None
 1.36A 1mjoB-4ovjA:
undetectable		 1mjoB-4ovjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 4 HIS A 177
ALA A 172
PHE A 171
GLY A 175
 None
 1.39A 1mjoA-4ovjA:
undetectable		 1mjoA-4ovjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 4 HIS A 177
ALA A 172
PHE A 171
GLY A 175
 None
 1.36A 1mjoD-4ovjA:
undetectable		 1mjoD-4ovjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.86A 1mnvD-4ovjA:
undetectable		 1mnvD-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		5 / 12 PHE A 379
LEU A 366
VAL A 344
ALA A  66
ALA A 349
 None
 1.30A 1q23A-4ovjA:
undetectable
1q23B-4ovjA:
undetectable		 1q23A-4ovjA:
18.87
1q23B-4ovjA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.85A 1qfiB-4ovjA:
undetectable		 1qfiB-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 6 THR A  64
GLN A 109
PHE A  52
ASN A 157
 None
 1.21A 1tt0A-4ovjA:
undetectable		 1tt0A-4ovjA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 6 THR A  64
GLN A 109
PHE A  52
ASN A 157
 None
 1.24A 1tt0B-4ovjA:
undetectable		 1tt0B-4ovjA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 6 THR A  64
GLN A 109
PHE A  52
ASN A 157
 None
 1.22A 1tt0C-4ovjA:
undetectable		 1tt0C-4ovjA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 6 THR A  64
GLN A 109
PHE A  52
ASN A 157
 None
 1.22A 1tt0D-4ovjA:
undetectable		 1tt0D-4ovjA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.73A 1unjF-4ovjA:
undetectable		 1unjF-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.84A 1unjF-4ovjA:
undetectable		 1unjF-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.76A 1unjL-4ovjA:
undetectable		 1unjL-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.81A 1unjL-4ovjA:
undetectable		 1unjL-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.77A 1unjR-4ovjA:
undetectable		 1unjR-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.80A 1unjR-4ovjA:
undetectable		 1unjR-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.82A 1unjW-4ovjA:
undetectable		 1unjW-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.76A 1unjX-4ovjA:
undetectable		 1unjX-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.81A 1unjX-4ovjA:
undetectable		 1unjX-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.77A 1unmE-4ovjA:
undetectable		 1unmE-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.84A 1unmE-4ovjA:
undetectable		 1unmE-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.82A 1unmF-4ovjA:
undetectable		 1unmF-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.80A 1unmF-4ovjA:
undetectable		 1unmF-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		5 / 10 LEU A 190
ILE A 189
VAL A 164
LEU A 298
PHE A 171
 None
 1.08A 1xp0A-4ovjA:
undetectable		 1xp0A-4ovjA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 8 PHE A  88
MET A 110
TYR A 118
TYR A 114
 None
 1.48A 1xqlA-4ovjA:
undetectable
1xqlB-4ovjA:
undetectable		 1xqlA-4ovjA:
21.62
1xqlB-4ovjA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 8 TYR A 118
TYR A 114
PHE A  88
MET A 110
 None
 1.43A 1xqlA-4ovjA:
undetectable
1xqlB-4ovjA:
undetectable		 1xqlA-4ovjA:
21.62
1xqlB-4ovjA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 257
THR A 259
PRO A 255
 None
 0.76A 209dC-4ovjA:
undetectable		 209dC-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 8 GLY A 132
THR A 137
ILE A 133
ASN A 342
 None
 1.04A 2a8tB-4ovjA:
undetectable		 2a8tB-4ovjA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		5 / 10 ALA A 389
ALA A 385
LEU A 381
LEU A 302
ALA A 163
 None
 1.00A 2bxeA-4ovjA:
undetectable		 2bxeA-4ovjA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		5 / 12 TYR A 243
LEU A 247
VAL A 253
SER A 277
ASP A 205
 None
 1.31A 2vqyA-4ovjA:
undetectable		 2vqyA-4ovjA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.68A 316dC-4ovjA:
undetectable		 316dC-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 6 PHE A 428
MET A 410
PHE A 407
PHE A 211
 None
 1.25A 3af3A-4ovjA:
undetectable		 3af3A-4ovjA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		5 / 12 LEU A 230
ASN A 224
GLY A 227
TRP A 208
LEU A 222
 None
 1.30A 3medA-4ovjA:
undetectable
3medB-4ovjA:
undetectable		 3medA-4ovjA:
23.24
3medB-4ovjA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A  49
VAL A  47
GLU A  72
 None
 0.66A 3v4tA-4ovjA:
undetectable
3v4tD-4ovjA:
undetectable		 3v4tA-4ovjA:
22.63
3v4tD-4ovjA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 PRO A 254
ASP A 204
GLU A 202
 None
 0.88A 3v4tC-4ovjA:
undetectable		 3v4tC-4ovjA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 THR A 259
PRO A 255
THR A 257
 None
 0.81A 4hivD-4ovjA:
undetectable		 4hivD-4ovjA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		3 / 3 ASP A 270
TRP A 244
SER A 277
 None
 1.07A 4lrhB-4ovjA:
undetectable		 4lrhB-4ovjA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		5 / 12 GLY A 312
LEU A 313
GLN A 217
VAL A 388
VAL A 164
 None
 1.10A 4wnwB-4ovjA:
undetectable		 4wnwB-4ovjA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 7 GLY A 251
GLN A 412
TYR A 416
ASP A 204
 None
 1.03A 5vlmE-4ovjA:
undetectable		 5vlmE-4ovjA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 7 GLY A 251
GLN A 412
TYR A 416
ASP A 204
 None
 1.15A 5vlmG-4ovjA:
undetectable		 5vlmG-4ovjA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		4 / 6 LEU A 298
ASP A 205
GLN A 415
GLU A 280
 None
 1.27A 6djzC-4ovjA:
undetectable		 6djzC-4ovjA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1
(Alicyclobacillus
acidocaldarius) 		5 / 12 ASN A 126
ILE A 323
VAL A 337
ILE A 107
PRO A 317
 None
 1.12A 6hlpA-4ovjA:
undetectable		 6hlpA-4ovjA:
21.54