SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ovm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		5 / 12 LEU A 132
LEU A  43
ARG A  27
ILE A  64
GLY A  60
 None
 1.25A 1g50B-4ovmA:
undetectable		 1g50B-4ovmA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		5 / 11 LEU A 132
LEU A  43
ARG A  27
ILE A  64
GLY A  60
 None
 1.26A 1g50C-4ovmA:
undetectable		 1g50C-4ovmA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		5 / 12 LEU A 132
LEU A  43
ARG A  27
ILE A  64
GLY A  60
 None
 1.23A 2j7xA-4ovmA:
undetectable		 2j7xA-4ovmA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		5 / 12 LEU A 132
LEU A  43
ARG A  27
ILE A  64
GLY A  60
 None
 1.20A 2yjaB-4ovmA:
undetectable		 2yjaB-4ovmA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		5 / 7 GLY A 129
ALA A 130
TRP A 131
ALA A  20
ASP A  23
 None
 1.15A 3ur0B-4ovmA:
undetectable		 3ur0B-4ovmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		4 / 7 TYR A 136
ILE A 118
THR A 100
GLY A  83
 None
 0.73A 4eq4A-4ovmA:
undetectable		 4eq4A-4ovmA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		4 / 8 TYR A 136
ILE A 118
THR A 100
GLY A  83
 None
 0.75A 4eq4B-4ovmA:
undetectable		 4eq4B-4ovmA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		4 / 7 TYR A 136
ILE A 118
THR A 100
GLY A  83
 None
 0.77A 4eqlA-4ovmA:
undetectable		 4eqlA-4ovmA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		4 / 7 TYR A 136
ILE A 118
THR A 100
GLY A  83
 None
 0.76A 4eqlB-4ovmA:
undetectable		 4eqlB-4ovmA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		5 / 12 LEU A 132
LEU A  43
ARG A  27
ILE A  64
GLY A  60
 None
 1.28A 4j26A-4ovmA:
undetectable		 4j26A-4ovmA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		4 / 6 TYR A 136
ILE A 118
THR A 100
GLY A  83
 None
 0.72A 4l39A-4ovmA:
undetectable		 4l39A-4ovmA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		4 / 7 TYR A 136
ILE A 118
THR A 100
GLY A  83
 None
 0.76A 4l39B-4ovmA:
undetectable		 4l39B-4ovmA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4ovm UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
carzinostaticus) 		5 / 11 LEU A 132
LEU A  43
ARG A  27
ILE A  64
GLY A  60
 None
 1.18A 5dxbB-4ovmA:
undetectable		 5dxbB-4ovmA:
18.94