SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ovr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 PHE A 150
ASN A 208
HIS A 230
VAL A 169
 None
GTR  A 403 (-3.0A)
None
None
 1.25A 1wu8A-4ovrA:
undetectable
1wu8C-4ovrA:
undetectable		 1wu8A-4ovrA:
24.84
1wu8C-4ovrA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 HIS A 230
GLY A  92
VAL A 308
LEU A 106
PRO A 107
 None
 1.00A 1zq9B-4ovrA:
undetectable		 1zq9B-4ovrA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 ARG A  88
THR A  93
ASN A 208
GLN A  34
 GTR  A 403 (-2.6A)
None
GTR  A 403 (-3.0A)
GTR  A 403 (-4.1A)
 1.00A 2jc9A-4ovrA:
undetectable		 2jc9A-4ovrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 LEU A  51
ARG A 256
SER A  30
VAL A 138
 None
 1.20A 2qd2A-4ovrA:
undetectable		 2qd2A-4ovrA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		3 / 3 GLU A 274
GLN A  34
ARG A  88
 None
GTR  A 403 (-4.1A)
GTR  A 403 (-2.6A)
 0.90A 2w3bB-4ovrA:
undetectable		 2w3bB-4ovrA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 ILE A 128
GLY A 125
PHE A 110
ILE A 320
 None
 0.85A 2y7wC-4ovrA:
5.0		 2y7wC-4ovrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 SER A 172
MET A 316
PHE A 110
ILE A 320
LEU A 137
 None
 1.28A 3aocC-4ovrA:
undetectable		 3aocC-4ovrA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 ILE A 291
ASP A 292
SER A 228
LEU A 182
LEU A 162
 None
 1.10A 3cjtK-4ovrA:
undetectable		 3cjtK-4ovrA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 9 ILE A 317
ILE A 320
MET A 316
VAL A 308
ILE A 128
 None
 1.16A 3p4wB-4ovrA:
undetectable		 3p4wB-4ovrA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 ILE A 317
ILE A 320
MET A 316
VAL A 308
ILE A 128
 None
 1.16A 3p4wD-4ovrA:
undetectable		 3p4wD-4ovrA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 ILE A  61
VAL A  63
ASP A  32
SER A  30
ILE A  87
 None
 1.18A 3vrjA-4ovrA:
undetectable
3vrjC-4ovrA:
undetectable		 3vrjA-4ovrA:
20.00
3vrjC-4ovrA:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 SER A 231
HIS A 230
ASN A 208
GLU A 207
GLU A 235
 None
None
GTR  A 403 (-3.0A)
None
GTR  A 403 (-2.9A)
 1.29A 4fevE-4ovrA:
0.2		 4fevE-4ovrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 ASN A 208
GLU A 207
GLU A 235
SER A 231
HIS A 230
 GTR  A 403 (-3.0A)
None
GTR  A 403 (-2.9A)
None
None
 1.28A 4fewE-4ovrA:
undetectable
4fewF-4ovrA:
0.7		 4fewE-4ovrA:
23.39
4fewF-4ovrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 SER A 231
HIS A 230
ASN A 208
GLU A 207
GLU A 235
 None
None
GTR  A 403 (-3.0A)
None
GTR  A 403 (-2.9A)
 1.28A 4gkhG-4ovrA:
0.0
4gkhH-4ovrA:
0.0		 4gkhG-4ovrA:
23.39
4gkhH-4ovrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 SER A 231
HIS A 230
ASN A 208
GLU A 207
GLU A 235
 None
None
GTR  A 403 (-3.0A)
None
GTR  A 403 (-2.9A)
 1.30A 4gkhK-4ovrA:
0.0
4gkhL-4ovrA:
0.0		 4gkhK-4ovrA:
23.39
4gkhL-4ovrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 SER A 231
HIS A 230
ASN A 208
GLU A 207
GLU A 235
 None
None
GTR  A 403 (-3.0A)
None
GTR  A 403 (-2.9A)
 1.31A 4gkiC-4ovrA:
undetectable
4gkiD-4ovrA:
undetectable		 4gkiC-4ovrA:
23.39
4gkiD-4ovrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 SER A 231
HIS A 230
ASN A 208
GLU A 207
GLU A 235
 None
None
GTR  A 403 (-3.0A)
None
GTR  A 403 (-2.9A)
 1.29A 4gkiG-4ovrA:
0.7
4gkiH-4ovrA:
undetectable		 4gkiG-4ovrA:
23.39
4gkiH-4ovrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 LEU A  51
ARG A 256
SER A  30
VAL A 138
 None
 1.21A 4klrA-4ovrA:
undetectable		 4klrA-4ovrA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 PRO A 107
GLU A 229
TRP A 270
ASP A 271
 None
 1.12A 4uacA-4ovrA:
5.7		 4uacA-4ovrA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		3 / 3 ASP A  32
ARG A 168
ARG A 148
 None
GTR  A 403 (-2.9A)
GTR  A 403 (-3.1A)
 0.97A 4x5iA-4ovrA:
undetectable		 4x5iA-4ovrA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 6 SER A 228
GLU A 229
ARG A 168
GLY A 205
 None
None
GTR  A 403 (-2.9A)
None
 0.94A 5cdnR-4ovrA:
undetectable
5cdnS-4ovrA:
undetectable		 5cdnR-4ovrA:
20.45
5cdnS-4ovrA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 6 CYH A 132
CYH A  98
LEU A  94
LEU A 238
 None
 1.18A 5hpuC-4ovrA:
undetectable
5hpuD-4ovrA:
undetectable		 5hpuC-4ovrA:
7.35
5hpuD-4ovrA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 ILE A 156
LEU A 162
MET A 179
LEU A 182
 None
 0.99A 5u4sB-4ovrA:
undetectable		 5u4sB-4ovrA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		3 / 3 ASP A 214
ASN A 215
ASP A  37
 None
 0.86A 5vopA-4ovrA:
undetectable		 5vopA-4ovrA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Xanthobacter
autotrophicus) 		3 / 3 ASP A 214
ASN A 215
ASP A  37
 None
 0.86A 5vopB-4ovrA:
undetectable		 5vopB-4ovrA:
22.95