SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ovt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 TYR A 120
ARG A 149
GLN A 176
 None
LFC  A 403 (-2.7A)
LFC  A 403 ( 4.7A)
 1.02A 1tw4A-4ovtA:
undetectable		 1tw4A-4ovtA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 7 GLY A 264
TYR A 261
SER A 267
PHE A 117
 None
 1.06A 2ackA-4ovtA:
undetectable		 2ackA-4ovtA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2002_0
(TRYPTOPHAN
HALOGENASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 PRO A 171
ILE A  88
TYR A 231
GLU A 208
ASN A 234
 LFC  A 403 (-4.0A)
LFC  A 403 (-3.9A)
None
None
LFC  A 403 ( 4.9A)
 1.47A 2oa1A-4ovtA:
undetectable		 2oa1A-4ovtA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2002_0
(TRYPTOPHAN
HALOGENASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 PRO A 171
LYS A  72
ILE A  88
GLU A 208
ASN A 234
 LFC  A 403 (-4.0A)
LFC  A 403 ( 2.8A)
LFC  A 403 (-3.9A)
None
LFC  A 403 ( 4.9A)
 1.35A 2oa1A-4ovtA:
undetectable		 2oa1A-4ovtA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 8 PRO A 107
VAL A 103
GLY A 102
MET A 175
 None
 1.01A 2qd5A-4ovtA:
undetectable		 2qd5A-4ovtA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 8 MET A  80
ALA A  79
GLY A 241
ILE A 137
 None
 0.79A 2zm9A-4ovtA:
undetectable		 2zm9A-4ovtA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 GLU A 208
ARG A 149
ASN A 209
TYR A 146
TYR A 105
 None
LFC  A 403 (-2.7A)
LFC  A 403 (-2.9A)
LFC  A 403 (-4.2A)
None
 1.39A 3ckzA-4ovtA:
undetectable		 3ckzA-4ovtA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		6 / 11 VAL A 170
ILE A 152
ILE A 157
PRO A 156
LEU A 163
THR A 195
 None
 1.45A 3clbA-4ovtA:
undetectable		 3clbA-4ovtA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		6 / 12 VAL A 170
ILE A 152
ILE A 157
PRO A 156
LEU A 163
THR A 195
 None
 1.46A 3clbC-4ovtA:
undetectable		 3clbC-4ovtA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		6 / 11 VAL A 170
ILE A 152
ILE A 157
PRO A 156
LEU A 163
THR A 195
 None
 1.43A 3hbbC-4ovtA:
undetectable		 3hbbC-4ovtA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 GLU A 208
ARG A 149
ASN A 209
TYR A 146
TYR A 105
 None
LFC  A 403 (-2.7A)
LFC  A 403 (-2.9A)
LFC  A 403 (-4.2A)
None
 1.36A 3sanA-4ovtA:
undetectable		 3sanA-4ovtA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 GLU A 208
ARG A 149
ASN A 209
TYR A 146
TYR A 105
 None
LFC  A 403 (-2.7A)
LFC  A 403 (-2.9A)
LFC  A 403 (-4.2A)
None
 1.37A 3sanB-4ovtA:
undetectable		 3sanB-4ovtA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 THR A  87
ILE A 238
TYR A 144
ASP A  41
PHE A  40
 None
 1.22A 3vw1D-4ovtA:
undetectable		 3vw1D-4ovtA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 GLU A 208
ARG A 149
ASN A 209
TYR A 146
TYR A 105
 None
LFC  A 403 (-2.7A)
LFC  A 403 (-2.9A)
LFC  A 403 (-4.2A)
None
 1.45A 4wa5A-4ovtA:
undetectable		 4wa5A-4ovtA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 SER A  67
ALA A  31
VAL A  30
 None
 0.49A 4x1iA-4ovtA:
undetectable		 4x1iA-4ovtA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 7 ILE A 151
MET A 183
ALA A 185
ILE A 168
 None
 0.75A 4y03A-4ovtA:
undetectable		 4y03A-4ovtA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 SER A  67
ALA A  31
VAL A  30
 None
 0.52A 5eypA-4ovtA:
undetectable		 5eypA-4ovtA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 6 ILE A 152
GLY A 147
ASN A 234
ILE A 211
 None
None
LFC  A 403 ( 4.9A)
None
 0.97A 5j4nB-4ovtA:
undetectable		 5j4nB-4ovtA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 SER A 267
ALA A 260
PRO A  39
ALA A 263
GLY A 264
 None
 1.30A 5tzoA-4ovtA:
undetectable		 5tzoA-4ovtA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4ovt TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 7 THR A 188
PHE A 180
LEU A 163
SER A 227
 None
 1.27A 5uxcA-4ovtA:
undetectable		 5uxcA-4ovtA:
22.01