SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ovx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 9 TYR A 267
THR A 301
LEU A 305
VAL A 283
GLY A 284
 None
 1.38A 1dz8A-4ovxA:
undetectable		 1dz8A-4ovxA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 9 TYR A 267
THR A 301
LEU A 305
VAL A 283
GLY A 284
 None
 1.36A 1dz8B-4ovxA:
undetectable		 1dz8B-4ovxA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 9 TYR A 267
THR A 301
LEU A 305
VAL A 283
GLY A 284
 None
 1.40A 1dz9B-4ovxA:
undetectable		 1dz9B-4ovxA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		4 / 7 TYR A 267
THR A 301
VAL A 283
GLY A 284
 None
 0.89A 2a1mA-4ovxA:
undetectable		 2a1mA-4ovxA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 9 TYR A 267
THR A 301
LEU A 305
VAL A 283
GLY A 284
 None
 1.36A 2a1oB-4ovxA:
undetectable		 2a1oB-4ovxA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 12 LEU A 204
GLY A 196
GLY A 162
GLY A 161
VAL A 207
 None
 0.55A 2avvA-4ovxA:
undetectable		 2avvA-4ovxA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 11 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.40A 2fkeA-4ovxA:
undetectable		 2fkeA-4ovxA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		3 / 3 TYR A 233
TYR A 164
GLY A 201
 None
 0.68A 3eteB-4ovxA:
undetectable
3eteD-4ovxA:
undetectable
3eteF-4ovxA:
undetectable		 3eteB-4ovxA:
20.12
3eteD-4ovxA:
20.12
3eteF-4ovxA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 11 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.42A 3o5rA-4ovxA:
undetectable		 3o5rA-4ovxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 10 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.38A 3uf8A-4ovxA:
undetectable		 3uf8A-4ovxA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 10 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.41A 3uqaA-4ovxA:
undetectable		 3uqaA-4ovxA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 12 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.22A 4drhA-4ovxA:
undetectable		 4drhA-4ovxA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 11 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.34A 4drjA-4ovxA:
undetectable		 4drjA-4ovxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		3 / 3 PHE A  59
TYR A  84
TYR A  89
 None
 0.92A 4ffwA-4ovxA:
undetectable		 4ffwA-4ovxA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		4 / 8 ALA A  58
GLU A 294
ILE A 298
ILE A  79
 None
 0.89A 4kttD-4ovxA:
undetectable		 4kttD-4ovxA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		4 / 8 THR A 265
VAL A 239
VAL A 283
VAL A 249
 None
 0.96A 4l4bA-4ovxA:
undetectable		 4l4bA-4ovxA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 10 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.33A 4laxA-4ovxA:
undetectable		 4laxA-4ovxA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		3 / 3 LEU A 305
LYS A 302
THR A 301
 None
 0.60A 4lj0A-4ovxA:
undetectable		 4lj0A-4ovxA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 10 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.26A 4qt3A-4ovxA:
undetectable		 4qt3A-4ovxA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCM_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 12 GLY A 122
GLU A 121
ASN A  86
ASN A 157
HIS A 194
 None
None
None
None
EDO  A 401 (-4.0A)
 1.33A 5ccmA-4ovxA:
undetectable		 5ccmA-4ovxA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 10 ASP A 165
LEU A 175
ALA A 171
SER A 160
THR A 218
 None
 1.26A 5m5cE-4ovxA:
2.7		 5m5cE-4ovxA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		3 / 3 SER A 250
ALA A 251
THR A 301
 None
 0.33A 5n0xB-4ovxA:
undetectable		 5n0xB-4ovxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 12 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.30A 6mkeA-4ovxA:
undetectable
6mkeD-4ovxA:
undetectable		 6mkeA-4ovxA:
14.89
6mkeD-4ovxA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 10 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.35A 6mkeC-4ovxA:
undetectable		 6mkeC-4ovxA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4ovx XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL
(Planctopirus
limnophila) 		5 / 10 TYR A 267
PHE A 222
VAL A 283
ILE A  48
ILE A 298
 None
 1.38A 6mkeD-4ovxA:
undetectable		 6mkeD-4ovxA:
14.89