SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ovy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		4 / 7 VAL A  62
LEU A 278
TYR A  42
LEU A 173
 None
 0.61A 1cqpA-4ovyA:
3.9
1cqpB-4ovyA:
3.9		 1cqpA-4ovyA:
22.04
1cqpB-4ovyA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 12 TYR A 199
VAL A 280
LEU A  70
SER A 184
TRP A 194
 None
None
None
EDO  A 407 ( 4.3A)
None
 1.38A 1mmkA-4ovyA:
undetectable		 1mmkA-4ovyA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 10 VAL A 106
LEU A 114
THR A 129
THR A 126
TRP A  97
 None
 1.22A 1rj6A-4ovyA:
undetectable		 1rj6A-4ovyA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 10 VAL A 106
LEU A 114
THR A 129
THR A 126
TRP A  97
 None
 1.15A 1rj6B-4ovyA:
undetectable		 1rj6B-4ovyA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		4 / 8 ASP A  65
TYR A 291
GLY A 260
ASP A 259
 CA  A 409 (-3.0A)
None
None
None
 0.86A 1rmtC-4ovyA:
10.3		 1rmtC-4ovyA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 11 LEU A 278
VAL A 280
ILE A  39
PHE A  64
LEU A  27
 None
 1.18A 2q72A-4ovyA:
undetectable		 2q72A-4ovyA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 12 LEU A 278
VAL A 280
ILE A  39
PHE A  64
LEU A  27
 None
 1.15A 2qb4A-4ovyA:
undetectable		 2qb4A-4ovyA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 11 LEU A 278
VAL A 280
ILE A  39
PHE A  64
LEU A  27
 None
 1.18A 2qeiA-4ovyA:
undetectable		 2qeiA-4ovyA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		4 / 8 GLY A 185
ILE A 279
VAL A 268
THR A  69
 EDO  A 407 (-3.6A)
None
None
None
 0.90A 2yoeB-4ovyA:
undetectable
2yoeC-4ovyA:
undetectable		 2yoeB-4ovyA:
22.54
2yoeC-4ovyA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 PRO A 251
GLU A 266
TYR A 267
 None
 0.67A 2zmbA-4ovyA:
undetectable		 2zmbA-4ovyA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 PHE A 154
CYH A 161
HIS A 151
 None
 1.27A 3u9fF-4ovyA:
undetectable		 3u9fF-4ovyA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 PHE A 154
CYH A 161
HIS A 151
 None
 1.21A 3u9fG-4ovyA:
undetectable		 3u9fG-4ovyA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 PHE A 154
CYH A 161
HIS A 151
 None
 1.20A 3u9fL-4ovyA:
undetectable		 3u9fL-4ovyA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 TYR A  42
ARG A  53
SER A  45
 None
 1.17A 4dr2I-4ovyA:
undetectable
4dr2J-4ovyA:
undetectable		 4dr2I-4ovyA:
17.67
4dr2J-4ovyA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		4 / 7 ASP A 235
ASP A  65
ASN A 257
GLU A  73
 EDO  A 407 (-3.7A)
CA  A 409 (-3.0A)
CA  A 409 (-2.8A)
CA  A 409 ( 4.1A)
 1.18A 4fexB-4ovyA:
undetectable		 4fexB-4ovyA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 TYR A  42
ARG A  53
SER A  45
 None
 1.22A 4lf7I-4ovyA:
undetectable
4lf7J-4ovyA:
undetectable		 4lf7I-4ovyA:
17.67
4lf7J-4ovyA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 TYR A  42
ARG A  53
SER A  45
 None
 1.22A 4lf8I-4ovyA:
undetectable
4lf8J-4ovyA:
undetectable		 4lf8I-4ovyA:
17.67
4lf8J-4ovyA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 10 THR A 283
GLU A  73
ASN A 257
LEU A 304
PHE A 289
 None
CA  A 409 ( 4.1A)
CA  A 409 (-2.8A)
None
None
 1.38A 4r3aB-4ovyA:
undetectable		 4r3aB-4ovyA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 12 GLY A 187
GLY A 185
ILE A 233
ASN A  66
LEU A  80
 None
EDO  A 407 (-3.6A)
None
None
None
 1.16A 5fa8A-4ovyA:
undetectable		 5fa8A-4ovyA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 TRP A  71
ILE A 182
SER A 184
 None
None
EDO  A 407 ( 4.3A)
 1.01A 5gqbA-4ovyA:
undetectable		 5gqbA-4ovyA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		5 / 12 GLY A 187
MET A 191
ALA A  83
LEU A  84
ALA A 119
 None
None
None
None
EDO  A 407 (-3.6A)
 1.35A 5jglB-4ovyA:
undetectable		 5jglB-4ovyA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 GLU A 266
TYR A 267
ARG A 250
 None
 0.81A 5uunA-4ovyA:
undetectable		 5uunA-4ovyA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE
(Planctopirus
limnophila) 		3 / 3 GLU A 266
TYR A 267
ARG A 250
 None
 0.80A 5uunB-4ovyA:
undetectable		 5uunB-4ovyA:
22.99