SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ow4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 4ow4 BETA-TERFOIL
DESIGNED BY FOLDING
NUCLEUS SYMMETRIC
EXPANSION
('PHIFOIL')
(synthetic
construct) 		4 / 6 ARG A 110
GLU A  18
LEU A 132
ASP A 127
 None
 1.19A 4cevA-4ow4A:
undetectable
4cevB-4ow4A:
undetectable		 4cevA-4ow4A:
16.38
4cevB-4ow4A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 4ow4 BETA-TERFOIL
DESIGNED BY FOLDING
NUCLEUS SYMMETRIC
EXPANSION
('PHIFOIL')
(synthetic
construct) 		4 / 6 ASP A 127
ARG A 110
GLU A  18
LEU A 132
 None
 1.20A 4cevA-4ow4A:
undetectable
4cevC-4ow4A:
undetectable		 4cevA-4ow4A:
16.38
4cevC-4ow4A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 4ow4 BETA-TERFOIL
DESIGNED BY FOLDING
NUCLEUS SYMMETRIC
EXPANSION
('PHIFOIL')
(synthetic
construct) 		4 / 6 ARG A 110
GLU A  18
LEU A 132
ASP A 127
 None
 1.20A 4cevD-4ow4A:
undetectable
4cevE-4ow4A:
undetectable		 4cevD-4ow4A:
16.38
4cevE-4ow4A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 4ow4 BETA-TERFOIL
DESIGNED BY FOLDING
NUCLEUS SYMMETRIC
EXPANSION
('PHIFOIL')
(synthetic
construct) 		4 / 6 ARG A 110
GLU A  18
LEU A 132
ASP A 127
 None
 1.19A 4cevE-4ow4A:
undetectable
4cevF-4ow4A:
undetectable		 4cevE-4ow4A:
16.38
4cevF-4ow4A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 4ow4 BETA-TERFOIL
DESIGNED BY FOLDING
NUCLEUS SYMMETRIC
EXPANSION
('PHIFOIL')
(synthetic
construct) 		5 / 11 ILE A  56
GLN A  63
LEU A  65
VAL A  73
LEU A  23
 None
 1.11A 4g1bB-4ow4A:
undetectable		 4g1bB-4ow4A:
17.79