SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ox3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 4ox3 PUTATIVE
CARBOXYPEPTIDASE
YODJ
(Bacillus
subtilis) 		3 / 3 TYR A 179
ASP A 162
ASP A 155
 None
 0.71A 4a6eA-4ox3A:
undetectable		 4a6eA-4ox3A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4ox3 PUTATIVE
CARBOXYPEPTIDASE
YODJ
(Bacillus
subtilis) 		5 / 12 TYR A  67
ILE A  80
ASN A  85
GLU A 126
VAL A  90
 None
 1.37A 4a97A-4ox3A:
undetectable
4a97B-4ox3A:
undetectable		 4a97A-4ox3A:
20.78
4a97B-4ox3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4ox3 PUTATIVE
CARBOXYPEPTIDASE
YODJ
(Bacillus
subtilis) 		4 / 8 SER A 183
PHE A 224
ILE A 226
VAL A 215
 None
 0.96A 4dx7B-4ox3A:
2.5		 4dx7B-4ox3A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 4ox3 PUTATIVE
CARBOXYPEPTIDASE
YODJ
(Bacillus
subtilis) 		5 / 11 ILE A 225
TYR A 228
ALA A 190
THR A 187
LEU A 263
 None
 1.14A 4g1bB-4ox3A:
undetectable		 4g1bB-4ox3A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4ox3 PUTATIVE
CARBOXYPEPTIDASE
YODJ
(Bacillus
subtilis) 		3 / 3 THR A 187
PRO A 102
ASP A 104
 None
 0.84A 5l8dB-4ox3A:
undetectable		 5l8dB-4ox3A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4ox3 PUTATIVE
CARBOXYPEPTIDASE
YODJ
(Bacillus
subtilis) 		3 / 3 THR A 187
PRO A 102
ASP A 104
 None
 0.84A 5mwuB-4ox3A:
undetectable		 5mwuB-4ox3A:
19.31