SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ox9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU Y  77
ALA Y  43
LEU Y  42
THR Y  33
ILE Y  64
 None
 1.10A 1mx8A-4ox9Y:
undetectable		 1mx8A-4ox9Y:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY Y  32
GLY Y  34
ASP Y  55
ALA Y  87
GLU Y  88
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
 0.70A 2gluA-4ox9Y:
12.5		 2gluA-4ox9Y:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ASP Y  30
LEU Y  31
GLY Y  32
GLY Y  34
LEU Y 110
 SFG  Y 301 ( 4.7A)
None
SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.0A)
 0.72A 2nxeB-4ox9Y:
3.5		 2nxeB-4ox9Y:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE Y 135
LEU Y 110
LEU Y 128
LEU Y 172
TYR Y 168
 None
SFG  Y 301 (-4.0A)
None
None
None
 1.22A 3adsA-4ox9Y:
undetectable		 3adsA-4ox9Y:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		3 / 3 TYR Y  51
GLU Y 136
ASP Y 181
 None
 0.79A 3bxoA-4ox9Y:
10.6		 3bxoA-4ox9Y:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		3 / 3 TYR Y  51
GLU Y 136
ASP Y 181
 None
 0.78A 3bxoB-4ox9Y:
10.1		 3bxoB-4ox9Y:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ASP Y  30
LEU Y  31
GLY Y  32
ASP Y  55
LEU Y 110
 SFG  Y 301 ( 4.7A)
None
SFG  Y 301 (-3.9A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
 0.82A 3cjtC-4ox9Y:
10.7		 3cjtC-4ox9Y:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA Y  43
ILE Y  68
PHE Y  50
ILE Y   3
ILE Y  52
 None
 1.07A 3clbB-4ox9Y:
undetectable		 3clbB-4ox9Y:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 GLY Y  32
GLY Y  34
ASP Y  55
ALA Y  87
GLU Y  88
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
 0.63A 3g88A-4ox9Y:
13.2		 3g88A-4ox9Y:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 GLY Y  32
GLY Y  34
ASP Y  55
ALA Y  87
GLU Y  88
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
 0.62A 3g88B-4ox9Y:
12.9		 3g88B-4ox9Y:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY Y  32
GLY Y  34
ASP Y  55
ALA Y  87
GLU Y  88
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
 0.70A 3g89A-4ox9Y:
13.2		 3g89A-4ox9Y:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 GLY Y  32
GLY Y  34
ASP Y  55
ALA Y  87
GLU Y  88
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
 0.71A 3g89B-4ox9Y:
13.1		 3g89B-4ox9Y:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY Y  32
GLY Y  34
ASP Y  55
ALA Y  87
GLU Y  88
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
 0.74A 3g8bA-4ox9Y:
13.1		 3g8bA-4ox9Y:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY Y  32
GLY Y  34
ASP Y  55
ALA Y  87
GLU Y  88
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
 0.73A 3g8bB-4ox9Y:
11.6		 3g8bB-4ox9Y:
21.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY Y  32
GLY Y  34
PRO Y  56
ALA Y  85
LEU Y 104
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.4A)
None
SFG  Y 301 (-4.6A)
 1.26A 3mteA-4ox9Y:
34.9		 3mteA-4ox9Y:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		9 / 12 GLY Y  32
GLY Y  34
PRO Y  56
VAL Y  57
ALA Y  86
ALA Y  87
LEU Y 104
THR Y 109
LEU Y 110
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-3.3A)
SFG  Y 301 (-4.0A)
 0.45A 3mteA-4ox9Y:
34.9		 3mteA-4ox9Y:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 GLY Y  32
GLY Y  34
PRO Y  56
VAL Y  57
ASN Y  60
LEU Y 104
THR Y 109
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
G  A1486 ( 3.9A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-3.3A)
 0.58A 3mteA-4ox9Y:
34.9		 3mteA-4ox9Y:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 GLY Y  32
PRO Y  56
ALA Y  86
ALA Y  87
THR Y 109
LEU Y 110
SER Y 195
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-4.4A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.3A)
SFG  Y 301 (-4.0A)
SFG  Y 301 ( 3.7A)
 0.63A 3mteA-4ox9Y:
34.9		 3mteA-4ox9Y:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MTE_A_SAMA220_1
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		4 / 4 ASN Y  38
ASP Y  55
GLU Y  88
TRP Y 197
 SFG  Y 301 ( 4.5A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-3.6A)
SFG  Y 301 (-3.5A)
 0.83A 3mteA-4ox9Y:
34.9		 3mteA-4ox9Y:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		8 / 12 GLY Y  32
GLY Y  34
ASN Y  38
PRO Y  56
VAL Y  57
ALA Y  85
LEU Y 104
PHE Y 105
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 ( 4.5A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
None
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.8A)
 1.49A 3mteB-4ox9Y:
34.2		 3mteB-4ox9Y:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		12 / 12 GLY Y  32
GLY Y  34
ASN Y  38
PRO Y  56
VAL Y  57
ALA Y  86
ALA Y  87
GLU Y  88
LEU Y 104
PHE Y 105
THR Y 109
LEU Y 110
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 ( 4.5A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.8A)
SFG  Y 301 (-3.3A)
SFG  Y 301 (-4.0A)
 0.65A 3mteB-4ox9Y:
34.2		 3mteB-4ox9Y:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 GLY Y  32
GLY Y  34
ASN Y  38
ALA Y  87
PHE Y 105
THR Y 109
TRP Y 197
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 ( 4.5A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-4.8A)
SFG  Y 301 (-3.3A)
SFG  Y 301 (-3.5A)
 1.48A 3p2kA-4ox9Y:
31.7		 3p2kA-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		11 / 12 GLY Y  32
GLY Y  34
ASN Y  38
PRO Y  56
ALA Y  86
ALA Y  87
LEU Y 104
PHE Y 105
THR Y 109
LEU Y 110
TRP Y 197
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 ( 4.5A)
SFG  Y 301 (-4.4A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.8A)
SFG  Y 301 (-3.3A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.5A)
 0.70A 3p2kA-4ox9Y:
31.7		 3p2kA-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		11 / 12 GLY Y  32
GLY Y  34
ASN Y  38
PRO Y  56
VAL Y  57
ALA Y  87
GLU Y  88
LEU Y 104
THR Y 109
LEU Y 110
TRP Y 197
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 ( 4.5A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.6A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-3.3A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.5A)
 0.73A 3p2kB-4ox9Y:
31.4		 3p2kB-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		11 / 12 GLY Y  32
GLY Y  34
PRO Y  56
VAL Y  57
ASN Y  60
ALA Y  86
ALA Y  87
LEU Y 104
PHE Y 105
LEU Y 110
TRP Y 197
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
G  A1486 ( 3.9A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.8A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-3.5A)
 0.64A 3p2kC-4ox9Y:
31.6		 3p2kC-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 5 ASN Y  38
ASP Y  55
GLU Y  88
THR Y 109
SER Y 195
 SFG  Y 301 ( 4.5A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-3.6A)
SFG  Y 301 (-3.3A)
SFG  Y 301 ( 3.7A)
 0.81A 3p2kC-4ox9Y:
31.6		 3p2kC-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		6 / 12 GLY Y  32
GLY Y  34
PRO Y  56
VAL Y  57
ALA Y  85
LEU Y 104
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
None
SFG  Y 301 (-4.6A)
 1.26A 3p2kD-4ox9Y:
30.9		 3p2kD-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		10 / 12 GLY Y  32
GLY Y  34
PRO Y  56
VAL Y  57
ALA Y  86
ALA Y  87
LEU Y 104
LEU Y 110
TYR Y 113
TRP Y 197
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.4A)
U  A1485 ( 4.7A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.0A)
None
SFG  Y 301 (-3.5A)
 0.70A 3p2kD-4ox9Y:
30.9		 3p2kD-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		9 / 12 GLY Y  32
PRO Y  56
ALA Y  86
ALA Y  87
LEU Y 104
LEU Y 110
TYR Y 113
SER Y 195
TRP Y 197
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-4.4A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.0A)
None
SFG  Y 301 ( 3.7A)
SFG  Y 301 (-3.5A)
 1.11A 3p2kD-4ox9Y:
30.9		 3p2kD-4ox9Y:
98.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P2K_D_SAMD6735_1
(16S RRNA METHYLASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		4 / 4 ASN Y  38
ASP Y  55
GLU Y  88
THR Y 109
 SFG  Y 301 ( 4.5A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-3.6A)
SFG  Y 301 (-3.3A)
 0.64A 3p2kD-4ox9Y:
30.9		 3p2kD-4ox9Y:
98.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY Y  32
GLY Y  36
ASN Y  38
ALA Y  87
LEU Y 110
 SFG  Y 301 (-3.9A)
None
SFG  Y 301 ( 4.5A)
SFG  Y 301 (-4.0A)
SFG  Y 301 (-4.0A)
 1.08A 3vywC-4ox9Y:
7.1		 3vywC-4ox9Y:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 9 GLY Y  34
LEU Y  31
ASP Y  30
ASN Y  38
ILE Y  54
 SFG  Y 301 (-3.1A)
None
SFG  Y 301 ( 4.7A)
SFG  Y 301 ( 4.5A)
None
 1.20A 3wdmA-4ox9Y:
undetectable		 3wdmA-4ox9Y:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE Y  68
VAL Y  81
ASP Y  55
THR Y  33
ILE Y  39
 None
None
SFG  Y 301 (-2.8A)
None
None
 1.38A 4xe0A-4ox9Y:
undetectable		 4xe0A-4ox9Y:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 GLY Y  32
GLY Y  34
ASP Y  55
PRO Y  56
GLU Y  88
LEU Y 104
LEU Y 110
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-2.8A)
SFG  Y 301 (-4.4A)
SFG  Y 301 (-3.6A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.0A)
 0.48A 5bw4A-4ox9Y:
26.3		 5bw4A-4ox9Y:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		6 / 12 GLY Y  32
GLY Y  34
PRO Y  56
ALA Y  86
LEU Y 104
LEU Y 110
 SFG  Y 301 (-3.9A)
SFG  Y 301 (-3.1A)
SFG  Y 301 (-4.4A)
SFG  Y 301 ( 4.1A)
SFG  Y 301 (-4.6A)
SFG  Y 301 (-4.0A)
 0.58A 5bw4B-4ox9Y:
27.5		 5bw4B-4ox9Y:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE
(Escherichia
coli) 		4 / 8 ILE Y 150
THR Y 139
VAL Y 138
SER Y 208
 None
 1.16A 6fbvC-4ox9Y:
undetectable		 6fbvC-4ox9Y:
10.57