SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oxp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HZ4_A_BEZA784_0 (MALT REGULATORY PROTEIN)	4oxp	RIBONUCLEASE E (Caulobacter vibrioides)	4 / 6	LEU A 224 LEU A 186 PRO A 188 MET A 187	None	1.23A	1hz4A-4oxpA: undetectable	1hz4A-4oxpA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_A_CHDA130_0 (FATTY ACID-BINDING PROTEIN)	4oxp	RIBONUCLEASE E (Caulobacter vibrioides)	5 / 12	LEU A 179 LEU A 186 LEU A 177 ILE A 265 THR A 256	None	0.95A	1tw4A-4oxpA: undetectable	1tw4A-4oxpA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_B_CHDB1130_0 (FATTY ACID-BINDING PROTEIN)	4oxp	RIBONUCLEASE E (Caulobacter vibrioides)	5 / 12	LEU A 179 LEU A 186 LEU A 177 ILE A 265 THR A 256	None	1.14A	1tw4B-4oxpA: undetectable	1tw4B-4oxpA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ACTA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	4oxp	RIBONUCLEASE E (Caulobacter vibrioides)	4 / 6	VAL A 150 TYR A 79 MET A 157 ILE A 74	None	1.28A	5iwuA-4oxpA: undetectable	5iwuA-4oxpA: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TWJ_A_SAMA201_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H)	4oxp	RIBONUCLEASE E (Caulobacter vibrioides)	5 / 12	LEU A 69 ILE A 59 GLY A 67 GLY A 170 HIS A 66	None	0.96A	5twjA-4oxpA: undetectable	5twjA-4oxpA: 21.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HZ4_A_BEZA784_0","MALT REGULATORY PROTEIN","4oxp","RIBONUCLEASE E","Caulobacter vibrioides",4,"LEU A 224;LEU A 186;PRO A 188;MET A 187","None","1.23A","1hz4A-4oxpA:undetectable","1hz4A-4oxpA:21.64"],["1TW4_A_CHDA130_0","FATTY ACID-BINDING PROTEIN","4oxp","RIBONUCLEASE E","Caulobacter vibrioides",5,"LEU A 179;LEU A 186;LEU A 177;ILE A 265;THR A 256","None","0.95A","1tw4A-4oxpA:undetectable","1tw4A-4oxpA:18.28"],["1TW4_B_CHDB1130_0","FATTY ACID-BINDING PROTEIN","4oxp","RIBONUCLEASE E","Caulobacter vibrioides",5,"LEU A 179;LEU A 186;LEU A 177;ILE A 265;THR A 256","None","1.14A","1tw4B-4oxpA:undetectable","1tw4B-4oxpA:18.28"],["5IWU_A_ACTA402_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","4oxp","RIBONUCLEASE E","Caulobacter vibrioides",4,"VAL A 150;TYR A  79;MET A 157;ILE A  74","None","1.28A","5iwuA-4oxpA:undetectable","5iwuA-4oxpA:22.01"],["5TWJ_A_SAMA201_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H","4oxp","RIBONUCLEASE E","Caulobacter vibrioides",5,"LEU A  69;ILE A  59;GLY A  67;GLY A 170;HIS A  66","None","0.96A","5twjA-4oxpA:undetectable","5twjA-4oxpA:21.11"]]