SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
3 / 3 LEU A 168
PHE A 207
ARG A  92
None
0.81A 1xdkF-4oy7A:
undetectable
1xdkF-4oy7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 12 LEU A 194
GLY A 131
ALA A 132
PRO A  41
ILE A 134
None
0.88A 2ienB-4oy7A:
undetectable
2ienB-4oy7A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
3 / 3 SER A 139
TYR A 138
HIS A 189
None
0.73A 2r2vD-4oy7A:
undetectable
2r2vD-4oy7A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 10 LEU A 194
GLY A 131
ALA A 132
GLY A 229
ILE A 134
None
0.89A 3ekvA-4oy7A:
undetectable
3ekvA-4oy7A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 11 LEU A 194
GLY A 131
ALA A 132
PRO A  41
ILE A 134
None
0.90A 3nu3B-4oy7A:
undetectable
3nu3B-4oy7A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 9 LEU A 194
GLY A 131
ALA A 132
GLY A 229
ILE A 134
None
0.99A 3oxvC-4oy7A:
undetectable
3oxvC-4oy7A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 12 LEU A 194
GLY A 131
ALA A 132
PRO A  41
ILE A 134
None
0.84A 3pwmB-4oy7A:
undetectable
3pwmB-4oy7A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 9 ASP A 107
SER A 114
ASN A 117
GLY A 100
ASP A  99
None
1.49A 3sfuA-4oy7A:
undetectable
3sfuA-4oy7A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 9 LEU A 194
GLY A 131
ALA A 132
GLY A 229
ILE A 134
None
0.93A 4rvjB-4oy7A:
undetectable
4rvjB-4oy7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 9 LEU A 194
GLY A 131
ALA A 132
GLY A 229
ILE A 134
None
0.92A 4rvjD-4oy7A:
undetectable
4rvjD-4oy7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
4 / 8 GLY A 188
GLN A 180
TYR A 190
SER A 139
None
0.94A 4wryA-4oy7A:
undetectable
4wryA-4oy7A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
4 / 8 GLY A 188
GLN A 180
TYR A 190
SER A 139
None
0.95A 4wrzA-4oy7A:
undetectable
4wrzA-4oy7A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 12 THR A 126
ARG A 200
SER A 201
GLY A 202
ALA A 204
None
1.33A 5l5zV-4oy7A:
undetectable
5l5zb-4oy7A:
undetectable
5l5zV-4oy7A:
21.70
5l5zb-4oy7A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 12 THR A 126
ARG A 200
SER A 201
GLY A 202
ALA A 204
None
1.33A 5l5zH-4oy7A:
undetectable
5l5zN-4oy7A:
undetectable
5l5zH-4oy7A:
21.70
5l5zN-4oy7A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 12 THR A 126
ARG A 200
SER A 201
GLY A 202
ALA A 204
None
1.40A 5lf3b-4oy7A:
undetectable
5lf3b-4oy7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 12 THR A 126
ARG A 200
SER A 201
GLY A 202
ALA A 204
None
1.40A 5lf3N-4oy7A:
undetectable
5lf3N-4oy7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
3 / 3 TYR A 116
SER A 114
TRP A 123
None
0.87A 5n8jB-4oy7A:
undetectable
5n8jB-4oy7A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
3 / 3 TYR A 116
SER A 114
TRP A 123
None
0.85A 5n8jA-4oy7A:
undetectable
5n8jA-4oy7A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
3 / 3 TYR A 116
SER A 114
TRP A 123
None
0.89A 5n8jD-4oy7A:
undetectable
5n8jD-4oy7A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)
4oy7 PUTATIVE SECRETED
CELLULOSE BINDING
PROTEIN

(Streptomyces
coelicolor)
5 / 12 LEU A 194
GLY A 131
ALA A 132
PRO A  41
ILE A 134
None
0.79A 6difB-4oy7A:
undetectable
6difB-4oy7A:
17.93