SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oy8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_H_SVRH511_2 (PHOSPHOLIPASE A2)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	4 / 5	VAL A 206 VAL A 159 THR A 133 THR A 208	None	1.24A	3bjwD-4oy8A: undetectable	3bjwD-4oy8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	4 / 8	GLY A 151 ALA A 152 ASP A 153 THR A 208	None	0.62A	3el0A-4oy8A: undetectable	3el0A-4oy8A: 19.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4GBO_A_CUA301_0 (E7)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	5 / 5	HIS A 43 ALA A 148 HIS A 150 GLN A 217 TYR A 219	ZN A 305 ( 3.1A) ACT A 311 ( 3.1A) ZN A 305 ( 3.2A) None None	0.57A	4gboA-4oy8A: 35.5	4gboA-4oy8A: 69.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4GBO_A_CUA301_0 (E7)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	4 / 5	HIS A 43 HIS A 214 GLN A 217 TYR A 219	ZN A 305 ( 3.1A) None None None	1.09A	4gboA-4oy8A: 35.5	4gboA-4oy8A: 69.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4GBO_B_CUB301_0 (E7)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	4 / 5	ALA A 148 HIS A 150 GLN A 217 TYR A 219	ACT A 311 ( 3.1A) ZN A 305 ( 3.2A) None None	0.59A	4gboB-4oy8A: 35.3	4gboB-4oy8A: 69.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4GBO_B_CUB301_0 (E7)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	4 / 5	HIS A 43 ALA A 148 HIS A 150 TYR A 219	ZN A 305 ( 3.1A) ACT A 311 ( 3.1A) ZN A 305 ( 3.2A) None	0.90A	4gboB-4oy8A: 35.3	4gboB-4oy8A: 69.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R1Z_A_AERA601_1 (CYP17A1 PROTEIN)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	5 / 9	ALA A 104 ILE A 209 ASP A 101 GLY A 100 ALA A 99	None	1.24A	4r1zA-4oy8A: undetectable	4r1zA-4oy8A: 20.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5UIZ_A_CUA301_0 (AA10A)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	5 / 5	HIS A 43 ALA A 148 HIS A 150 GLN A 217 TYR A 219	ZN A 305 ( 3.1A) ACT A 311 ( 3.1A) ZN A 305 ( 3.2A) None None	0.58A	5uizA-4oy8A: 35.5	5uizA-4oy8A: 69.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5UIZ_A_CUA301_0 (AA10A)	4oy8	PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN (Streptomyces coelicolor)	4 / 5	HIS A 43 HIS A 214 GLN A 217 TYR A 219	ZN A 305 ( 3.1A) None None None	1.10A	5uizA-4oy8A: 35.5	5uizA-4oy8A: 69.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJW_H_SVRH511_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",4,"VAL A 206;VAL A 159;THR A 133;THR A 208","None","1.24A","3bjwD-4oy8A:undetectable","3bjwD-4oy8A:20.74"],["3EL0_A_1UNA201_1","PROTEASE","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",4,"GLY A 151;ALA A 152;ASP A 153;THR A 208","None","0.62A","3el0A-4oy8A:undetectable","3el0A-4oy8A:19.23"],["4GBO_A_CUA301_0","E7","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",5,"HIS A  43;ALA A 148;HIS A 150;GLN A 217;TYR A 219"," ZN A 305 ( 3.1A);ACT A 311 ( 3.1A); ZN A 305 ( 3.2A);None;None","0.57A","4gboA-4oy8A:35.5","4gboA-4oy8A:69.89"],["4GBO_A_CUA301_0","E7","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",4,"HIS A  43;HIS A 214;GLN A 217;TYR A 219"," ZN A 305 ( 3.1A);None;None;None","1.09A","4gboA-4oy8A:35.5","4gboA-4oy8A:69.89"],["4GBO_B_CUB301_0","E7","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",4,"ALA A 148;HIS A 150;GLN A 217;TYR A 219","ACT A 311 ( 3.1A); ZN A 305 ( 3.2A);None;None","0.59A","4gboB-4oy8A:35.3","4gboB-4oy8A:69.89"],["4GBO_B_CUB301_0","E7","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",4,"HIS A  43;ALA A 148;HIS A 150;TYR A 219"," ZN A 305 ( 3.1A);ACT A 311 ( 3.1A); ZN A 305 ( 3.2A);None","0.90A","4gboB-4oy8A:35.3","4gboB-4oy8A:69.89"],["4R1Z_A_AERA601_1","CYP17A1 PROTEIN","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",5,"ALA A 104;ILE A 209;ASP A 101;GLY A 100;ALA A  99","None","1.24A","4r1zA-4oy8A:undetectable","4r1zA-4oy8A:20.27"],["5UIZ_A_CUA301_0","AA10A","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",5,"HIS A  43;ALA A 148;HIS A 150;GLN A 217;TYR A 219"," ZN A 305 ( 3.1A);ACT A 311 ( 3.1A); ZN A 305 ( 3.2A);None;None","0.58A","5uizA-4oy8A:35.5","5uizA-4oy8A:69.89"],["5UIZ_A_CUA301_0","AA10A","4oy8","PUTATIVE SECRETED CELLULOSE-BINDING PROTEIN","Streptomyces coelicolor",4,"HIS A  43;HIS A 214;GLN A 217;TYR A 219"," ZN A 305 ( 3.1A);None;None;None","1.10A","5uizA-4oy8A:35.5","5uizA-4oy8A:69.89"]]