SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 4oyy CUTINASE
(Humicola
insolens) 		5 / 12 LEU A   9
GLY A   8
VAL A  58
ALA A  43
LEU A  46
 None
 1.19A 1gs4A-4oyyA:
undetectable		 1gs4A-4oyyA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 4oyy CUTINASE
(Humicola
insolens) 		4 / 6 GLY A  27
SER A 105
ILE A 169
HIS A 173
 None
 0.90A 1yajF-4oyyA:
7.0		 1yajF-4oyyA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 4oyy CUTINASE
(Humicola
insolens) 		4 / 4 GLY A  27
SER A 105
ILE A 169
HIS A 173
 None
 0.88A 1yajJ-4oyyA:
5.4		 1yajJ-4oyyA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 4oyy CUTINASE
(Humicola
insolens) 		5 / 12 ILE A 144
ALA A 114
VAL A  38
LEU A 131
LEU A  22
 None
 1.28A 2rctA-4oyyA:
undetectable		 2rctA-4oyyA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 4oyy CUTINASE
(Humicola
insolens) 		5 / 10 ILE A  55
GLY A  57
VAL A  58
VAL A  99
ILE A  21
 None
 1.05A 3oxvB-4oyyA:
undetectable		 3oxvB-4oyyA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4oyy CUTINASE
(Humicola
insolens) 		5 / 12 GLY A  27
GLY A 102
ALA A  25
ALA A 114
SER A 116
 None
 1.10A 3sudA-4oyyA:
undetectable		 3sudA-4oyyA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 4oyy CUTINASE
(Humicola
insolens) 		4 / 5 SER A 105
GLY A 133
THR A  37
ASP A 160
 None
 1.00A 4eohA-4oyyA:
2.2		 4eohA-4oyyA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4oyy CUTINASE
(Humicola
insolens) 		4 / 8 LEU A  22
ILE A 111
VAL A 115
GLY A 128
 None
 0.85A 4eq4B-4oyyA:
undetectable		 4eq4B-4oyyA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 4oyy CUTINASE
(Humicola
insolens) 		5 / 12 ILE A 144
ALA A 114
VAL A  38
LEU A 131
LEU A  22
 None
 1.34A 4qynA-4oyyA:
undetectable		 4qynA-4oyyA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 4oyy CUTINASE
(Humicola
insolens) 		5 / 12 LEU A 118
VAL A  99
VAL A  58
TYR A  62
THR A  75
 None
 1.21A 5v1tA-4oyyA:
undetectable		 5v1tA-4oyyA:
17.38