SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oz5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		3 / 3 TRP A 128
HIS A 138
LYS A 135
 None
HEM  A 201 ( 3.2A)
None
 1.40A 1l7xA-4oz5A:
undetectable		 1l7xA-4oz5A:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 7 LEU A  26
GLU A  39
LEU A  69
ALA A  67
 None
 0.93A 1sn0B-4oz5A:
undetectable
1sn0D-4oz5A:
undetectable		 1sn0B-4oz5A:
25.00
1sn0D-4oz5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA602_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 5 HIS A  50
ILE A   5
PRO A  49
ASP A 109
 None
 1.32A 2f7fA-4oz5A:
0.5		 2f7fA-4oz5A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 5 THR A 117
ILE A 102
GLU A  94
PHE A  86
 None
None
None
HEM  A 201 ( 3.7A)
 1.29A 4ac9C-4oz5A:
undetectable		 4ac9C-4oz5A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 5 THR A 117
ILE A 102
GLU A  94
PHE A  86
 None
None
None
HEM  A 201 ( 3.7A)
 1.26A 4acaC-4oz5A:
undetectable		 4acaC-4oz5A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 6 LEU A  26
ASN A  24
LEU A 116
VAL A  54
 None
 1.14A 4okbA-4oz5A:
undetectable		 4okbA-4oz5A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 6 PHE A 153
ARG A  79
PHE A  82
TYR A 113
 None
 1.08A 4uciA-4oz5A:
undetectable		 4uciA-4oz5A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 7 PHE A 153
ARG A  79
PHE A  82
TYR A 113
 None
 1.07A 4uciB-4oz5A:
undetectable		 4uciB-4oz5A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 6 TYR A  52
ASP A 111
ILE A  72
TYR A 158
 None
 1.28A 5igyA-4oz5A:
undetectable		 5igyA-4oz5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 6 HIS A  50
ILE A  37
TYR A 162
TYR A 158
 None
 1.12A 5ih0A-4oz5A:
undetectable		 5ih0A-4oz5A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 8 ILE A  25
TYR A   7
THR A   6
ILE A   5
 None
 0.92A 5mzrE-4oz5A:
undetectable		 5mzrE-4oz5A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4oz5 BACILLUS SUBTILIS
HMOB
(Bacillus
subtilis) 		4 / 7 TYR A 162
LEU A 116
TYR A   7
VAL A 114
 None
 1.28A 6g2pA-4oz5A:
undetectable		 6g2pA-4oz5A:
18.40